Search Results - "Waters, A.P"

Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites by Franke-Fayard, B., Djokovic, D., Dooren, M.W., Ramesar, J., Waters, A.P., Falade, M.O., Kranendonk, M., Martinelli, A., Cravo, P., Janse, C.J.

“…We report two improved assays for in vitro and in vivo screening of chemicals with potential anti-malarial activity against the blood stages of the rodent…”
Get full text

Distinct roles for pbs21 and pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei by Sidén-Kiamos, I, Vlachou, D, Margos, G, Beetsma, A, Waters, A P, Sinden, R E, Louis, C

“…We have developed an in vitro culture system for early sporogonic stages of Plasmodium berghei, which can be used to study developmental events normally taking…”
Get full text

Comparative genomics in Plasmodium: a tool for the identification of genes and functional analysis by Thompson, J., Janse, C.J., Waters, A.P.

“…Comparative genomics allows inferences to be drawn about the coding potential of related genomes, and the evolutionary forces that have influenced genome…”
Get full text

Genomics and epigenetics of sexual commitment in Plasmodium by Bechtsi, D.P., Waters, A.P.

“…[Display omitted] •Recent work has unravelled some of the earliest known molecular events regulating sexual development in Plasmodium.•AP2-G is the ApiAP2…”
Get full text

Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model by Janse, C J, Waters, A P, Kos, J, Lugt, C B

“…The in vitro and in vivo antimalarial activity of artemisinin, artesunate and dihydroartemisinin has been compared using the Plasmodium berghei-rodent model…”
Get more information

Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry by Stunnenberg, Hendrik G, Mann, Matthias, Lasonder, Edwin, Ishihama, Yasushi, Andersen, Jens S, Vermunt, Adriaan M. W, Pain, Arnab, Sauerwein, Robert W, Eling, Wijnand M. C, Hall, Neil, Waters, Andrew P

“…The annotated genomes of organisms define a 'blueprint' of their possible gene products. Post-genome analyses attempt to confirm and modify the annotation and…”
Get full text

Plasmodium: the developmentally regulated ribosome by Li, J, McConkey, G A, Rogers, M J, Waters, A P, McCutchan, T R

Get more information

Plasmodium berghei: The application of cultivation and purification techniques to molecular studies of malaria parasites by Janse, C.J., Waters, A.P.

“…Species of malaria parasites that infect rodents provide models for the study of the biology of malaria parasites that infect humans. In this article, Chris…”
Get full text

Malaria Vaccines: Back to the Future? by Waters, A. P., Mota, M. M., van Dijk, M. R., Janse, C. J.

“…Malaria is the scourge of many developing countries, particularly those in sub-Saharan Africa, claiming several million lives each year. Here, Waters et al…”
Get full text

Stable transfection of malaria parasite blood stages by Dijk, M.R. van (University of Leiden, Leiden, Netherlands.), Waters, A.P, Janse, C.J

“…Genetic manipulation of malaria parasites would revolutionize the study of this group of pathogens and have implications for vaccine and drug development. This…”
Get full text

Transfection of Malaria Parasites by Waters, A.P., Thomas, A.W., van Dijk, M.R., Janse, C.J.

“…The stable genetic transformation of three phylogenetically diverse species ofPlasmodium,the parasitic etiological agent of malaria, is now possible. The…”
Get full text

Gene expression in Plasmodium berghei ookinetes and early oocysts in a co-culture system with mosquito cells by Vontas, John, Siden-Kiamos, Inga, Papagiannakis, Giorgos, Karras, Marianna, Waters, Andrew P., Louis, Christos

“…Using an in vitro development system for Plasmodium berghei sporogonic stages and microarray technology we examined parasite gene expression during ookinete…”
Get full text

Matters arising—editorial comment by Waters, A.P

Get full text

Plasmodium falciparum appears to have arisen as a result of lateral transfer between avian and human hosts by Waters, A.P. (National Institute of Allergy and Infectious Diseases, Bethesda, MD), Higgins, D.G, McCutchan, T.F

“…It has been proposed that the acquisition of Plasmodium falciparum by man is a relatively recent event and that the sustained presence of this disease in man…”
Get full text

Structurally Distinct, Stage-Specific Ribosomes Occur in Plasmodium by Gunderson, J. H., Sogin, M. L., Wollett, G., Hollingdale, M., De La Cruz, V. F., Waters, A. P., McCutchan, T. F.

“…Two structurally distinct nuclear genes code for cytoplasmic small subunit ribosomal RNA's in the parasite Plasmodium berghei. Stable transcripts from one of…”
Get full text

The ribosomal RNA genes of Plasmodium by Waters, A P

Get more information

Plasmodium: Genus-Conserved Primers for Species Identification and Quantitation by Li, J., Wirtz, R.A., Mcconkey, G.A., Sattabongkot, J., Waters, A.P., Rogers, M.J., Mccutchan, T.F.

“…Stable RNAs have regions of primary sequence that are nearly identical in every member of the Plasmodium genus and not found in the host or in other common…”
Get full text

Plasmodium falciparum vaccine candidate antigen PF83/AMA-1 is expressed in the rodent malaria P. berghei: infected mice produce PF83/AMA-1 antibodies by van der Wel, A.M., Kocken, C.H.M., Dubbeld, M.A.D., Janse, C.J., Waters, A.P., Thomas, A.W.

Get full text

Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen by Deans, J A, Knight, A M, Jean, W C, Waters, A P, Cohen, S, Mitchell, G H

“…A minor Plasmodium knowlesi 66 kD antigen, which plays an essential role in merozoite invasion, has been shown to be stable in distinct variants and strains of…”
Get more information

Sixty-six kilodalton-related antigens of Plasmodium knowlesi are merozoite surface antigens associated with the apical prominence by Thomas, A W, Bannister, L H, Waters, A P

“…We have previously reported that Fab fragments of a monoclonal antibody to the 66 kD-related antigens of Plasmodium knowlesi inhibit merozoite invasion of…”
Get more information