Search Results - "Water, Jorrit J"
-
1
An ingestible self-orienting system for oral delivery of macromolecules
Published in Science (American Association for the Advancement of Science) (08-02-2019)“…Biomacromolecules have transformed our capacity to effectively treat diseases; however, their rapid degradation and poor absorption in the gastrointestinal…”
Get full text
Journal Article -
2
Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2014)“…[Display omitted] •We prepared complex coacervates of lysozyme and hyaluronic acid.•The binding stoichiometry was 0.1 bound lysozyme molecule per hyaluronic…”
Get full text
Journal Article -
3
Chitosan-Based Nano-Embedded Microparticles: Impact of Nanogel Composition on Physicochemical Properties
Published in Pharmaceutics (22-12-2016)“…Chitosan-based nanogels have been widely applied as drug delivery vehicles. Spray-drying of said nanogels allows for the preparation of dry powder…”
Get full text
Journal Article -
4
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors
Published in Nature biotechnology (01-01-2022)“…Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the…”
Get full text
Journal Article -
5
Exploring the potential for rosacea therapeutics of siRNA dispersion in topical emulsions
Published in Experimental dermatology (01-03-2019)“…Rosacea is a prevalent skin condition dependent on the individual genetic profile. The current pharmacological management of this condition is mostly based on…”
Get full text
Journal Article -
6
Potential of surface-eroding poly(ethylene carbonate) for drug delivery to macrophages
Published in International journal of pharmaceutics (25-09-2016)“…[Display omitted] Films composed of poly(ethylene carbonate) (PEC), a biodegradable polymer, were compared with poly(lactide-co-glycolide) (PLGA) films loaded…”
Get full text
Journal Article -
7
Molecular weight-dependent degradation and drug release of surface-eroding poly(ethylene carbonate)
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2017)“…[Display omitted] Poly(ethylene carbonate) (PEC) is a unique biomaterial showing significant potential for controlled drug delivery applications. The current…”
Get full text
Journal Article -
8
Ingestible transiently anchoring electronics for microstimulation and conductive signaling
Published in Science advances (01-08-2020)“…Ingestible electronic devices enable noninvasive evaluation and diagnosis of pathologies in the gastrointestinal (GI) tract but generally cannot…”
Get full text
Journal Article -
9
Poly(ethylene carbonate)‐containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages
Published in Journal of pharmacy and pharmacology (01-08-2018)“…Objective Pulmonary delivery of antibiotics will decrease the required dose for efficient treatment of lung infections and reduce systemic side effects of the…”
Get full text
Journal Article -
10
Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin
Published in Pharmaceutical research (01-08-2015)“…Purpose Cationic host defence peptides constitute a promising class of therapeutic drug leads with a wide range of therapeutic applications, including…”
Get full text
Journal Article -
11
In silico product design of pharmaceuticals
Published in Asian journal of pharmceutical sciences (01-08-2016)“…The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may…”
Get full text
Journal Article -
12
Exploring the potential for rosacea therapeutics of si RNA dispersion in topical emulsions
Published in Experimental dermatology (01-03-2019)“…Rosacea is a prevalent skin condition dependent on the individual genetic profile. The current pharmacological management of this condition is mostly based on…”
Get full text
Journal Article