Search Results - "Watenpaugh, Keith"
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The League of Nations' Rescue of Armenian Genocide Survivors and the Making of Modern Humanitarianism, 1920—1927
Published in The American historical review (01-12-2010)“…The essay centers of the efforts by the League of Nations to rescue women and children survivors of the 1915 Armenian Genocide. This rescue -- a seemingly…”
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The Drowned, the Saved, and the Forgotten: Genocide Survivors and Modern Humanitarianism
Published in International journal of Middle East studies (01-05-2016)“…Dominant narratives of the Eastern Mediterranean's 20th century exclude the study of Western humanitarianism and refugee survivors of the 1915 genocide of the…”
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Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class
Published in Journal of medicinal chemistry (27-08-1998)“…A broad screening program previously identified phenprocoumon (1) as a small molecule template for inhibition of HIV protease. Subsequent modification of this…”
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4
The atomic-resolution structure of human caspase-8, a key activator of apoptosis
Published in Structure (London) (15-09-1999)“…Background: Caspases are a family of cysteine proteases that have important intracellular roles in inflammation and apoptosis. Caspase-8 activates downstream…”
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Structure-Based Design of Novel HIV Protease Inhibitors: Sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors
Published in Journal of medicinal chemistry (07-06-1996)“…The low oral bioavailability and rapid biliary excretion of peptide-derived HIV protease inhibitors have limited their utility as potential therapeutic agents…”
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MIDDLE-CLASS MODERNITY AND THE PERSISTENCE OF THE POLITICS OF NOTABLES IN INTER-WAR SYRIA
Published in International journal of Middle East studies (01-05-2003)“…From Paris in June 1928, Edmond Rabbath (1901–91) sent to Saעdallah al-Jabiri (1893–1947) his recently published L'évolution politique de la Syrie sous mandat…”
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Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors
Published in Journal of medicinal chemistry (01-09-1994)Get full text
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"Are There Any Children for Sale?": Genocide and the Transfer of Armenian Children (1915-1922)
Published in Journal of human rights (01-07-2013)“…The forced transfer of children from one group to another is considered an element of the crime of genocide, yet this subject has attracted little scholarly…”
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Structure-Based Design of Nonpeptidic HIV Protease Inhibitors: The Sulfonamide-Substituted Cyclooctylpyranones
Published in Journal of medicinal chemistry (28-03-1997)“…Recently, cyclooctylpyranone derivatives with m-carboxamide substituents (e.g. 2c) were identified as potent, nonpeptidic HIV protease inhibitors, but these…”
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10
Cation binding to the integrin CD11b I domain and activation model assessment
Published in Structure (London) (15-07-1998)“…Background: The integrin family of cell-surface receptors mediate cell adhesion through interactions with the extracellular matrix or other cell-surface…”
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Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors
Published in Journal of medicinal chemistry (01-09-1995)“…The low oral bioavailability and rapid biliary excretion of peptide-derived HIV protease inhibitors have limited their utility as potential therapeutic agents…”
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Structure-Based Design of HIV Protease Inhibitors: 5,6-Dihydro-4-hydroxy-2-pyrones as Effective, Nonpeptidic Inhibitors
Published in Journal of medicinal chemistry (08-11-1996)“…From a broad screening program, the 4-hydroxycoumarin phenprocoumon (I) was previously identified as a lead template with HIV protease inhibitory activity. The…”
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13
Jan Hermans (1933‐2018): Red‐blooded biophysicists study hemoglobin
Published in Proteins, structure, function, and bioinformatics (01-03-2019)Get full text
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The Cyclin-dependent Kinases cdk2 and cdk5 Act by a Random, Anticooperative Kinetic Mechanism
Published in The Journal of biological chemistry (21-12-2001)“…cdk2·cyclin E and cdk5·p25 are two members of the cyclin-dependent kinase family that are potential therapeutic targets for oncology and Alzheimer’s disease,…”
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Cleansing the cosmopolitan city: historicism, journalism and the Arab nation in the post-Ottoman eastern Mediterranean
Published in Social history (London) (01-02-2005)“…The collapse of the Ottoman Empire in the weak of World War I left an ideological and political vacuum in the cosmopolitan cities of the eastern Mediterranean…”
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“Creating Phantoms”: Zaki al-Arsuzi, the Alexandretta Crisis, and the Formation of Modern Arab Nationalism in Syria
Published in International journal of Middle East studies (01-08-1996)“…This quotation may be nothing more than a well-turned phrase by its author, Zaki al-Arsuzi. Nonetheless, it illustrates a dilemma that young men like him faced…”
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Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors
Published in Journal of medicinal chemistry (01-05-1995)“…A unique strategy for the enhancement of secondary binding of an inhibitor to an enzyme has been demonstrated in the design of new human immunodeficiency virus…”
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Structure-Based Design of Sulfonamide-Substituted Non-Peptidic HIV Protease Inhibitors
Published in Journal of medicinal chemistry (01-12-1995)Get full text
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19
Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures
Published in Journal of molecular biology (05-03-1991)“…The focus of this study has been to determine the conformation of the holoprotein of recombinant flavodoxin from Desulfovibrio vulgaris with the FMN in each of…”
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Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors
Published in Journal of medicinal chemistry (25-10-1996)Get full text
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