Search Results - "Watch, Brennan T"

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  1. 1
    Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis

    Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis by Wubben, Thomas J, Chaudhury, Sraboni, Watch, Brennan T, Stuckey, Jeanne A, Weh, Eric, Fernando, Roshini, Goswami, Moloy, Pawar, Mercy, Rech, Jason C, Besirli, Cagri G

    Published in Pharmaceuticals (Basel, Switzerland) (06-05-2023)
    “…Treatment options are lacking to prevent photoreceptor death and subsequent vision loss. Previously, we demonstrated that reprogramming metabolism via the…”
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    Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease

    Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease by Yuan, Xinrui, Jiang, Hua, Fu, Denggang, Robida, Aaron, Rajanayake, Krishani, Yuan, Hebao, Wen, Bo, Sun, Duxin, Watch, Brennan T., Chinnaswamy, Krishnapriya, Stuckey, Jeanne A., Paczesny, Sophie, Rech, Jason C., Yang, Chao-Yie

    Published in Bioorganic & medicinal chemistry (01-10-2022)
    “…[Display omitted] An elevated plasma level of soluble ST2 (sST2) is a risk biomarker for graft-versus-host disease (GVHD) and death in patients receiving…”
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