Search Results - "Watanabe, Kikuko"

Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2 by Murakami, Makoto, Nakashima, Karin, Kamei, Daisuke, Masuda, Seiko, Ishikawa, Yukio, Ishii, Toshiharu, Ohmiya, Yoshihiro, Watanabe, Kikuko, Kudo, Ichiro

“…Current evidence suggests that two forms of prostaglandin (PG) E synthase (PGES), cytosolic PGES and membrane-bound PGES (mPGES) -1, preferentially lie…”
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Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure by Bertrand, Jacques A, Woodward, David F, Sherwood, Joseph M, Spenlehauer, Alice, Silvestri, Cristoforo, Piscitelli, Fabiana, Marzo, Vincenzo Di, Yamazaki, Maya, Sakimura, Kenji, Inoue, Yoko, Watanabe, Kikuko, Overby, Darryl R

“…•Prostamide/Prostaglandin F Synthase (PM/PGFS) is involved in the biosynthesis of prostaglandin F2α (PGF2α) and prostamide F2α from arachidonic acid and…”
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Identification and Characterization of a Novel Type of Membrane-Associated Prostaglandin E Synthase by Tanikawa, Naomi, Ohmiya, Yoshihiro, Ohkubo, Hiroaki, Hashimoto, Katsuyuki, Kangawa, Kenji, Kojima, Masami, Ito, Seiji, Watanabe, Kikuko

“…Membrane-associated prostaglandin E synthase (mPGE synthase) was previously purified to apparent homogeneity from the microsomal fraction of bovine heart…”
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Crystal Structure of Human Prostaglandin F Synthase (AKR1C3) by Komoto, Junichi, Yamada, Taro, Watanabe, Kikuko, Takusagawa, Fusao

“…Prostaglandin H2 (PGH2) formed from arachidonic acid is an unstable intermediate and is efficiently converted into more stable arachidonate metabolites (PGD2,…”
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Two pathways for prostaglandin F2α synthesis by the primate periovulatory follicle by Dozier, Brandy L, Watanabe, Kikuko, Duffy, Diane M

“…Prostaglandin E2 (PGE2) has been identified as a PG necessary for ovulation, but the ovulatory gonadotropin surge also increases PGF2α levels in primate…”
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Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system by Yoshikawa, Keisuke, Takei, Shiro, Hasegawa-Ishii, Sanae, Chiba, Yoichi, Furukawa, Ayako, Kawamura, Noriko, Hosokawa, Masanori, Woodward, David F, Watanabe, Kikuko, Shimada, Atsuyoshi

“…Abstract Prostaglandin (PG) F2α is a product of cyclooxygenase (COX)-catalyzed metabolism of arachidonic acid and exerts biological functions in various…”
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Crystal Structure and Possible Catalytic Mechanism of Microsomal Prostaglandin E Synthase Type 2 (mPGES-2) by Yamada, Taro, Komoto, Junichi, Watanabe, Kikuko, Ohmiya, Yoshihiro, Takusagawa, Fusao

“…Prostaglandin (PG) H 2 (PGH 2), formed from arachidonic acid, is an unstable intermediate and is converted efficiently into more stable arachidonate…”
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Prostaglandin synthases with thioredoxin domain by Watanabe, Kikuko

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Molecular Characterization of a Novel Type of Prostamide/Prostaglandin F Synthase, Belonging to the Thioredoxin-like Superfamily by Moriuchi, Hiroshi, Koda, Noriko, Okuda-Ashitaka, Emiko, Daiyasu, Hiromi, Ogasawara, Kensuke, Toh, Hiroyuki, Ito, Seiji, Woodward, David F., Watanabe, Kikuko

“…Prostaglandin F (PGF) ethanolamide (prostamide F) synthase, which catalyzed the reduction of prostamide H2 to prostamide F2α, was found in mouse and swine…”
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Expression of Key Prostaglandin Synthases in Equine Endometrium During Late Diestrus and Early Pregnancy by BOERBOOM, Derek, BROWN, Kristy A, VAILLANCOURT, Denis, POITRAS, Pierre, GOFF, Alan K, WATANABE, Kikuko, DORE, Monique, SIROIS, Jean

“…Luteolysis in domestic species is mediated by the release of luteolytic pulses of prostaglandin (PG) F 2α by the uterus at the end of diestrus, which must be…”
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Regulation of prostaglandin biosynthesis by interleukin-1 in cultured bovine endometrial cells by Tanikawa, Michiyo, Lee, Hwa-Yong, Watanabe, Kikuko, Majewska, Magdalena, Skarzynski, Dariusz J, Park, Soo-Bong, Lee, Dong-Seok, Park, Choon-Keun, Acosta, Tomas J, Okuda, Kiyoshi

“…Interleukin-1 (IL1) has been shown to be a potent stimulator of prostaglandin (PG) production in bovine endometrium. The aim of the present study was to…”
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Purification and characterization of membrane-bound prostaglandin E synthase from bovine heart by Watanabe, Kikuko, Kurihara, Kayoko, Suzuki, Toshiko

“…Prostaglandin (PG) E synthase was solubilized with 6 mM sodium deoxycholate from the microsomal fraction of bovine hearts. The enzyme was purified by about…”
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Synthesis of prostaglandin F ethanolamide by prostaglandin F synthase and identification of Bimatoprost as a potent inhibitor of the enzyme: new enzyme assay method using LC/ESI/MS by Koda, Noriko, Tsutsui, Yasutaka, Niwa, Haruki, Ito, Seiji, Woodward, David F, Watanabe, Kikuko

“…Prostaglandin (PG) D 2 ethanolamide (prostamide D 2) was reduced to 9α,11β-PGF 2 ethanolamide (9α,11β-prostamide F 2) by PGF synthase, which also catalyzes the…”
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Localization of cyclooxygenases-1 and -2, and prostaglandin F synthase in human kidney and renal cell carcinoma by Sakurai, Madoka, Oishi, Kenji, Watanabe, Kikuko

“…Prostaglandin (PG)F 2α is one of the major prostanoids produced by the kidney, and its renal synthesis is regulated by sodium depletion, potassium depletion,…”
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Coordinate Regulation of Prostaglandin Metabolism for Induction of Parturition in Mice by Winchester, Sandra K, Imamura, Takuji, Gross, Gil A, Muglia, Lisa M, Vogt, Sherri K, Wright, Jason, Watanabe, Kikuko, Tai, Hsin-Hsiung, Muglia, Louis J

“…Prostaglandins are essential for the initiation of parturition in mice. The peak in uterine prostaglandin F2α levels occurs at d 19.0 of gestation, just before…”
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cDNA Cloning, Expression, and Mutagenesis Study of Liver-type Prostaglandin F Synthase by Suzuki, Toshiko, Fujii, Yutaka, Miyano, Masashi, Chen, Lan-Ying, Takahashi, Tomohiro, Watanabe, Kikuko

“…Prostaglandin (PG) F synthase catalyzes the reduction of PGD2 to 9α,11β-PGF2 and that of PGH2 to PGF2α on the same molecule. PGF synthase has at least two…”
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Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2 by Watanabe, Kikuko, Ohkubo, Hiroaki, Niwa, Haruki, Tanikawa, Naomi, Koda, Noriko, Ito, Seiji, Ohmiya, Yoshihiro

“…The amino acid sequence of membrane-associated prostaglandin (PG) E synthase-2 (mPGE synthase-2), which has a broad specificity in its thiol requirement for a…”
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Immunocytochemical localization of lung-type prostaglandin F synthase in the rat spinal cord by Suzuki-Yamamoto, Toshiko, Toida, Kazunori, Tsuruo, Yoshihiro, Watanabe, Kikuko, Ishimura, Kazunori

“…Prostaglandin F synthase, producing prostaglandin F 2α and 9α,11β-prostaglandin F 2, has at least two isozymes, lung-type and liver-type ones. The present…”
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Prostaglandin F synthase by Watanabe, Kikuko

“…Prostaglandin (PG) F 2 is synthesized via three pathways from PGE 2, PGD 2, or PGH 2 by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-, 11-endoperoxide…”
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Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach by Ikeda, Sakahiro, Okuda-Ashitaka, Emiko, Masu, Yasuo, Suzuki, Toshiko, Watanabe, Kikuko, Nakao, Masafumi, Shingu, Koh, Ito, Seiji

“…In contrast to hepatic hydrosteroid dehydrogenases (HSDs) of the aldo-keto reductase family (AKR1C), little is known about a stomach one. From a mouse stomach…”
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