Search Results - "Watanabe, Kevin"

Development of monolithic SOI pixel sensors capable of fine measurements of space and time by Murayama, Hitoshi, Hara, Kazuhiko, Yamauchi, Hiroki, Abe, Ryuhei, Iwanami, Shikie, Watanabe, Kevin, Okada, Yui, Tsuboyama, Toru, Arai, Yasuo, Miyoshi, Toshinobu, Kurachi, Ikuo, Haba, Junji, Togawa, Manabu, Ikegami, Yoichi, Nishimura, Ryutaro, Ishikawa, Akimasa, Ono, Shun, Li, Taohan, Yamada, Miho

“…Silicon-on-insulator (SOI) for fine measurement of space and time (SOFIST) is designed taking full advantage of advanced SOI monolithic pixel detector…”
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Gain-of-function mutations in granulocyte colony–stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation by Zhang, Haijiao, Coblentz, Cody, Watanabe-Smith, Kevin, Means, Sophie, Means, Jasmine, Maxson, Julia E., Tyner, Jeffrey W.

“…Granulocyte colony–stimulating factor (G-CSF or CSF3) and its receptor CSF3R regulate granulopoiesis, neutrophil function, and hematopoietic stem cell…”
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Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia by Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.

“…Acute Myeloid Leukemia (AML) develops due to the acquisition of mutations from multiple functional classes. Here, we demonstrate that activating mutations in…”
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Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia by Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.

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Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations by Watanabe-Smith, Kevin, Godil, Jamila, Agarwal, Anupriya, Tognon, Cristina, Druker, Brian

“…The identification and functional validation of potentially oncogenic mutations in leukemia is an essential step toward a future of personalized targeted…”
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Automated decision tree to evaluate genetic abnormalities when determining prognostic risk in acute myeloid leukemia by Watanabe-Smith, Kevin, Druker, Brian J, Tyner, Jeffrey W, Edwards, 5th, David K

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Military service in Vietnam and the risk of death from trauma and selected cancers by Watanabe, Kevin K, Kang, Han K

“…The postservice mortality of a cohort of 10,716 US Marine veterans who served in Vietnam was compared with that of 9,346 Marine veterans who did not serve in…”
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Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model by Zhang, Qing-Shuo, Marquez-Loza, Laura, Sheehan, Andrea M., Watanabe-Smith, Kevin, Eaton, Laura, Benedetti, Eric, Major, Angela, Schubert, Kathryn, Deater, Matthew, Joseph, Eric, Grompe, Markus

“…Fanconi anemia (FA) patients suffer from progressive bone marrow failure and often develop cancers. Previous studies showed that antioxidants tempol and…”
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Mortality Patterns among Vietnam Veterans: A 24-Year Retrospective Analysis by Watanabe, Kevin K., Kang, Han K.

“…The mortality experience of 33,833 US Army and Marine Corps Vietnam veterans who died during 1965--1988 was compared with that of 36,797 deceased non-Vietnam…”
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The Relationship between Transformational Leadership and Employee Engagement in an Agile Environment by Watanabe, Kevin K

“…Prior research recommended that an Agile leader who supports employees can significantly impact the success of a project and increase job satisfaction and…”
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Proportionate mortality among US Army Vietnam veterans who served in military region I by Bullman, T A, Kang, H K, Watanabe, K K

“…A proportionate mortality study was conducted to determine if the post-service mortality experience of 6,668 Army Vietnam veterans who served in Military…”
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Evaluation of the Safety of Rh Immunoglobulin by Monitoring Viral Markers among Rh-Negative Female Blood Donors by Watanabe, Kevin K., Busch, Michael P., Schreiber, George B., Zuck, Thomas F.

“…Background and Objectives: Although immunoglobulin (lg) preparations including Rhlg have been noted for their record of safety, recent reports of hepatitis C…”
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Mortality among Vietnam veterans: with methodological considerations by Watanabe, K K, Kang, H K, Thomas, T L

“…The Department of Veterans Affairs previously conducted a proportionate mortality study of Army and Marine Vietnam-era veterans who died during 1965 through…”
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CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells by Edwards, David K., Watanabe-Smith, Kevin, Rofelty, Angela, Damnernsawad, Alisa, Laderas, Ted, Lamble, Adam, Lind, Evan F., Kaempf, Andy, Mori, Motomi, Rosenberg, Mara, d'Almeida, Amanda, Long, Nicola, Agarwal, Anupriya, Sweeney, David Tyler, Loriaux, Marc, McWeeney, Shannon K., Tyner, Jeffrey W.

“…To identify new therapeutic targets in acute myeloid leukemia (AML), we performed small-molecule and small-interfering RNA (siRNA) screens of primary AML…”
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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance by Joshi, Sunil K., Nechiporuk, Tamilla, Bottomly, Daniel, Piehowski, Paul D., Reisz, Julie A., Pittsenbarger, Janét, Kaempf, Andy, Gosline, Sara J.C., Wang, Yi-Ting, Hansen, Joshua R., Gritsenko, Marina A., Hutchinson, Chelsea, Weitz, Karl K., Moon, Jamie, Cendali, Francesca, Fillmore, Thomas L., Tsai, Chia-Feng, Schepmoes, Athena A., Shi, Tujin, Arshad, Osama A., McDermott, Jason E., Babur, Ozgun, Watanabe-Smith, Kevin, Demir, Emek, D'Alessandro, Angelo, Liu, Tao, Tognon, Cristina E., Tyner, Jeffrey W., McWeeney, Shannon K., Rodland, Karin D., Druker, Brian J., Traer, Elie

“…Our study details the stepwise evolution of gilteritinib resistance in FLT3-mutated acute myeloid leukemia (AML). Early resistance is mediated by the bone…”
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RGL4 over Expression Correlates with Variation in Midostaurin Response in FLT3-ITD Mutant AML Samples by Rosenberg, Mara, Tognon, Cristina E., Watanabe-Smith, Kevin M, Borate, Uma

“…Introduction: Acute Myeloid Leukemia (AML) is a heterogenous malignancy with the most common genomic alterations including mutations in NPM1, DNMT3A, and FLT3…”
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Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms by Joshi, Sunil K., Qian, Kristin, Bisson, William H., Watanabe-Smith, Kevin, Huang, Ariane, Bottomly, Daniel, Traer, Elie, Tyner, Jeffrey W., McWeeney, Shannon K., Davare, Monika A., Druker, Brian J., Tognon, Cristina E.

“…Much of what is known about the neurotrophic receptor tyrosine kinase (NTRK) genes in cancer was revealed through identification and characterization of…”
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Determining the sensitivity of primary acute myeloid leukemia (AML) samples with FLT3-ITD or FLT3-D835 mutations to FLT3 inhibitors using an ex vivo drug sensitivity screen by Rosenberg, Mara, Fan, Guang, Watanabe-Smith, Kevin, Tognon, Cristina, Druker, Brian J., Tyner, Jeffrey, Loriaux, Marc

“…Abstract only…”
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Factors Predicting Response and Resistance to Midostaurin in FLT3 Positive and FLT3 Negative AML in 483 Primary AML Patient Samples by Watanabe-Smith, Kevin, Rosenberg, Mara, Bucy, Taylor, Tyner, Jeffrey W., Borate, Uma

“…Introduction: Midostaurin is an FDA approved, multi-target tyrosine kinase(TK) inhibitor shown to inhibit the FLT3 kinase and have therapeutic benefit in FLT3…”
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Distinct Mechanisms of Receptor Activation Are Associated with CSF3R Gain-of-Function Mutations by Zhang, Haijiao, Maxson, Julia E., Watanabe-Smith, Kevin M, Coblentz, Cody, Tyner, Jeffrey W.

“…Activating mutations in granulocyte colony-stimulating factor receptor (CSF3R), are found in the extracellular, the membrane proximal, the transmembrane and…”
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