Search Results - "Wastall, Laura M."
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CIP2A expression predicts recurrences of tamoxifen-treated breast cancer
Published in Tumor biology (01-10-2017)“…CIP2A is emerging as an oncoprotein overexpressed commonly across many tumours and generally correlated with higher tumour grade and therapeutic resistance…”
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2
MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer
Published in British journal of cancer (15-10-2019)“…Background Cancer-associated fibroblasts (CAFs) are known to impact on tumour behaviour, but the mechanisms controlling this are poorly understood. Methods…”
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Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy
Published in British journal of cancer (16-03-2021)“…Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts…”
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4
Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer
Published in Oncogene (22-04-2021)“…Triple negative breast cancer (TNBC) is challenging to treat successfully because targeted therapies do not exist. Instead, systemic therapy is typically…”
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MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-11-2018)“…MicroRNAs and RNA-binding proteins exert regulation on >60% of coding genes, yet interplay between them is little studied. Canonical microRNA binding occurs by…”
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Accuracy of classification of invasive lobular carcinoma on needle core biopsy of the breast
Published in Journal of clinical pathology (01-12-2016)“…Although the UK National Institute for Health and Care Excellence guidelines recommend that in patients with biopsy-proven invasive lobular carcinoma (ILC),…”
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