Search Results - "Wassenberg, Deena"
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1
The Role of the Aryl Hydrocarbon Receptor Pathway in Mediating Synergistic Developmental Toxicity of Polycyclic Aromatic Hydrocarbons to Zebrafish
Published in Toxicological sciences (01-08-2006)“…Planar halogenated aromatic hydrocarbons (pHAHs), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin), show strong binding affinity for the aryl hydrocarbon…”
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2
Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment
Published in Toxicological sciences (01-09-2008)“…Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants. Traditionally, much of the research has focused on the carcinogenic…”
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3
Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity
Published in PloS one (05-05-2010)“…In order to generate hypotheses regarding the mechanisms by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin) causes toxicity, we analyzed global gene…”
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4
Synergistic Embryotoxicity of Polycyclic Aromatic Hydrocarbon Aryl Hydrocarbon Receptor Agonists with Cytochrome P4501A Inhibitors in Fundulus heteroclitus
Published in Environmental health perspectives (01-12-2004)“…Widespread contamination of aquatic systems with polycyclic aromatic hydrocarbons (PAHs) has led to concern about effects of PAHs on aquatic life. Some PAHs…”
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5
Gender Performance Gaps Across Different Assessment Methods and the Underlying Mechanisms: The Case of Incoming Preparation and Test Anxiety
Published in Frontiers in education (Lausanne) (27-09-2019)“…A persistent “gender penalty” in exam performance disproportionately impacts women in large introductory science courses, where exam grades generally account…”
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6
Considering the Role of “Need for Cognition” in Students' Acceptance of Climate Change & Evolution
Published in The American biology teacher (01-04-2015)“…Anthropogenic climate change (ACC) and evolution are examples of issues that are perceived differently by scientists and the general public. Within the…”
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7
Open Inquiry versus Broadly Relevant Short-Term Research Experiences for Non-Biology Majors
Published in Journal of microbiology & biology education (01-01-2021)“…Undergraduate student participation in course-based research experiences results in many positive outcomes, but there is a lack of evidence demonstrating which…”
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8
Effects of the polycyclic aromatic hydrocarbon heterocycles, carbazole and dibenzothiophene, on in vivo and in vitro cyp1a activity and polycyclic aromatic hydrocarbon-derived embryonic deformities
Published in Environmental toxicology and chemistry (01-10-2005)“…Heterocyclic derivatives of polycyclic aromatic hydrocarbons (PAHs) are often significant components of environmental contaminant mixtures; however, their…”
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In Vivo and in Vitro Inhibition of CYP1A-Dependent Activity in Fundulus heteroclitus by the Polynuclear Aromatic Hydrocarbon Fluoranthene
Published in Toxicology and applied pharmacology (15-12-2001)“…Certainpolynuclear aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (BaP) induce CYP1A-dependent enzyme activities. Because PAHs are ubiquitous…”
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10
Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories
Published in Environmental toxicology and chemistry (01-10-2003)“…Wildcaught killifish from a contaminated site on the Elizabeth River (VA, USA) are refractory to induction of cytochrome P4501A (CYP1A, measured as catalytic…”
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11
The chlorinated AHR ligand 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) promotes reactive oxygen species (ROS) production during embryonic development in the killifish ( Fundulus heteroclitus)
Published in Aquatic toxicology (05-01-2006)“…Exposure to dioxin-like chemicals that activate the aryl hydrocarbon receptor (AHR) can result in increased cellular and tissue production of reactive oxygen…”
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12
Effects of the polycyclic aromatic hydrocarbon heterocycles, carbazole and dibenzothiophene, on in vivo and in vitro cypia activity and polycyclic aromatic hydrocarbon-derived embryonic deformities
Published in Environmental toxicology and chemistry (01-10-2005)“…Herocyclic derivatives of polycyclic aromatic hydrocarbons (PAHs) are often significant components of environmental contaminant mixtures; however, their…”
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Journal Article -
13
Effects of single and combined exposures to benzo(a)pyrene and 3,3′4,4′5-pentachlorobiphenyl on EROD activity and development in Fundulus heteroclitus
Published in Marine environmental research (01-09-2002)“…The goal of this study was to assess the interactive effects of a polynuclear aromatic hydrocarbon (PAH), benzo(a)pyrene (BaP), and a co-planar halogenated…”
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14
Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors
Published in Marine environmental research (01-08-2004)“…The goal of these experiments was to explore the relationship between cytochrome P4501A (CYP1A) induction and the teratogenicity of sediments from the Atlantic…”
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Journal Article Conference Proceeding -
15
Do Small Classes in Higher Education Reduce Performance Gaps in STEM?
Published in Bioscience (01-08-2018)“…Performance gaps in science are well documented, and an examination of underlying mechanisms that lead to underperformance and attrition of women and…”
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16
Smaller Classes Promote Equitable Student Participation in STEM
Published in Bioscience (01-08-2019)“…As science, technology, engineering, and mathematics (STEM) classrooms in higher education transition from lecturing to active learning, the frequency of…”
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17
Open-Inquiry vs. Broadly Relevant Short-Term Research Experiences for Non-Biology Majors
Published in Journal of microbiology & biology education (30-04-2021)“…Undergraduate student participation in course-based research experiences results in many positive outcomes, but there is a lack of evidence demonstrating which…”
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Journal Article -
18
What Determines Student Acceptance of Politically Controversial Scientific Conclusions?
Published in Journal of college science teaching (01-11-2017)“…Certain scientific conclusions are controversial, in that they are rejected by a substantial proportion of nonscientists despite an overwhelming scientific…”
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Journal Article -
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Synergistic Embryotoxicity of Polycyclic Aromatic Hydrocarbon Aryl Hydrocarbon Receptor Agonists with Cytochrome P4501A Inhibitors in Fundulus heterclitus
Published in Environmental health perspectives (01-12-2004)“…While a strong, positive relationship has been found between the ability of PAHs to bind the aryl hydrocarbon receptor (AHR) and their induction of cytochrome…”
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Journal Article -
20
Interactive effects of polycyclic aromatic hydrocarbons on cytochrome P4501A activity and embryonic development in the killifish Fundulus heteroclitus
Published 01-01-2004“…Polycyclic aromatic hydrocarbons (PAHs) are compounds composed of two or more fused aromatic rings that originate from the incomplete combustion of organic…”
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Dissertation