Search Results - "Wasowicz, Marguerite Y"
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Ex Vivo and In Vivo Lentivirus-Mediated Transduction of Airway Epithelial Progenitor Cells
Published in Current gene therapy (01-01-2015)“…A key challenge in pulmonary gene therapy for cystic fibrosis is to provide long-term correction of the genetic defect. This may be achievable by targeting…”
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The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways
Published in Biomaterials (01-03-2010)“…Abstract We have assessed whether viscoelastic gels known to inhibit mucociliary clearance can increase lipid-mediated gene transfer. Methylcellulose or…”
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Limitations of the murine nose in the development of nonviral airway gene transfer
Published in American journal of respiratory cell and molecular biology (01-07-2010)“…A clinical program to assess whether lipid GL67A-mediated gene transfer can ameliorate cystic fibrosis (CF) lung disease is currently being undertaken by the…”
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A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis
Published in Efficacy and mechanism evaluation (01-07-2016)“…Background Cystic fibrosis (CF) is a chronic, life-limiting disease caused by mutations in the CF transmembrane conductance regulator ( CFTR ) gene leading to…”
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