Search Results - "Wasik, Urszula"

Tau protein modifications and interactions: their role in function and dysfunction by Mietelska-Porowska, Anna, Wasik, Urszula, Goras, Marcelina, Filipek, Anna, Niewiadomska, Grazyna

“…Tau protein is abundant in the central nervous system and involved in microtubule assembly and stabilization. It is predominantly associated with axonal…”
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Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis by Wasik, Urszula, Milkiewicz, Małgorzata, Kempinska-Podhorodecka, Agnieszka, Milkiewicz, Piotr

“…In response to oxidative stress, nuclear factor (erythroid-derived 2)-like2 (Nrf2) induces expression of cytoprotective genes. The Nrf2 pathway is controlled…”
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Enhanced expression of miR-21 and miR-150 is a feature of anti-mitochondrial antibody-negative primary biliary cholangitis by Wasik, Urszula, Kempinska-Podhorodecka, Agnieszka, Bogdanos, Dimitrios P, Milkiewicz, Piotr, Milkiewicz, Malgorzata

“…Anti-mitochondrial-autoantibodies (AMA) remain a hallmark of Primary Biliary Cholangitis (PBC) however approximately 10% of patients test negative for these…”
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Melatonin Protects Cholangiocytes from Oxidative Stress-Induced Proapoptotic and Proinflammatory Stimuli via miR-132 and miR-34 by Ostrycharz, Ewa, Wasik, Urszula, Kempinska-Podhorodecka, Agnieszka, Banales, Jesus M, Milkiewicz, Piotr, Milkiewicz, Malgorzata

“…Biosynthesis of melatonin by cholangiocytes is essential for maintaining the function of biliary epithelium. However, this cytoprotective mechanism appears to…”
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The CacyBP/SIP Protein is Sumoylated in Neuroblastoma NB2a Cells by Wasik, Urszula, Filipek, Anna

“…The Calcyclin binding protein and Siah-1 interacting protein (CacyBP/SIP) protein is highly expressed in mammalian brain as well as in neuroblastoma NB2a cells…”
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Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR by Elias, Elwyn, Milkiewicz, Piotr, Bogdanos, Dimitrios P., Barbier, Olivier, Urasinska, Elzbieta, Blatkiewicz, Malgorzata, Milkiewicz, Małgorzata, Wasik, Urszula, Klak, Marta, Wunsch, Ewa, Bielicki, Dariusz

“…Background/Aim. Sulphotransferase 2A1 (SULT2A1) exerts hepatoprotective effects. Transcription of SULT2A1 gene is induced by pregnane-X-receptor (PXR) and can…”
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Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study by Milkiewicz, Malgorzata, Bogdanos, Dimitrios P., Rigopoulou, Eirini I., Norman, Gary L., Wunsch, Ewa, Wasik, Urszula, Milkiewicz, Piotr

“…Background. Recent GWAS in primary biliary cholangitis (PBC) showed strong associations with SNPs located within interleukin-12 receptor (IL12R) beta-2…”
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Non-nuclear function of sumoylated proteins by Wasik, Urszula, Filipek, Anna

“…Post-translational modification by the SUMO moiety is now regarded as one of the key regulatory modifications in eukaryotic cells. Up to now, plenty of…”
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Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway by Kempinska-Podhorodecka, Agnieszka, Milkiewicz, Malgorzata, Wasik, Urszula, Ligocka, Joanna, Zawadzki, Michał, Krawczyk, Marek, Milkiewicz, Piotr

“…Primary biliary cholangitis (PBC) is an immune-mediated cholestatic disease. Vitamin D receptor (VDR)-dependent signaling constrains an inflammatory response…”
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Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease by Wunsch, Ewa, Milkiewicz, Małgorzata, Wasik, Urszula, Trottier, Jocelyn, Kempińska-Podhorodecka, Agnieszka, Elias, Elwyn, Barbier, Olivier, Milkiewicz, Piotr

“…Cholestasis induces adaptive mechanisms protecting the liver against bile acids (BA) toxicity including modulation of BA synthesis. Whether fibroblast growth…”
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Influence of S100A6 on CacyBP/SIP Phosphorylation and Elk-1 Transcriptional Activity in Neuroblastoma NB2a Cells by Wasik, Urszula, Kadziolka, Beata, Kilanczyk, Ewa, Filipek, Anna

“…ABSTRACT In this work, we have found that casein kinase II (CKII) phosphorylates the CacyBP/SIP protein under in vitro conditions and have mapped the…”
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CacyBP/SIP phosphatase activity in neuroblastoma NB2a and colon cancer HCT116 cells by Kilanczyk, Ewa, Wasik, Urszula, Filipek, Anna

“…Recently, we have reported that CacyBP/SIP could be a novel phosphatase for ERK1/2 kinase. In this work, we analyzed the CacyBP/SIP phosphatase activity toward…”
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Calcyclin binding protein and Siah-1 interacting protein in Alzheimer's disease pathology: neuronal localization and possible function by Wasik, Urszula, Schneider, Gabriela, Mietelska-Porowska, Anna, Mazurkiewicz, Marcin, Fabczak, Hanna, Weis, Serge, Zabke, Claudia, Harrington, Charles R, Filipek, Anna, Niewiadomska, Grazyna

“…Abstract The calcyclin binding protein and Siah-1 interacting protein (CacyBP/SIP) protein was shown to play a role in the organization of microtubules. In…”
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