Search Results - "Waseem, Rashid"
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FNDC5/Irisin: Physiology and Pathophysiology
Published in Molecules (Basel, Switzerland) (08-02-2022)“…A sedentary lifestyle or lack of physical activity increases the risk of different diseases, including obesity, diabetes, heart diseases, certain types of…”
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Characterization of advanced glycation end products and aggregates of irisin: Multispectroscopic and microscopic approaches
Published in Journal of cellular biochemistry (01-01-2023)“…Glycation of proteins leading to the formation of advanced glycation end products (AGEs) has been demonstrated to contribute to the pathogenesis of several…”
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MAP/Microtubule Affinity Regulating Kinase 4 Inhibitory Potential of Irisin: A New Therapeutic Strategy to Combat Cancer and Alzheimer's Disease
Published in International journal of molecular sciences (12-10-2021)“…Irisin is a clinically significant protein playing a valuable role in regulating various diseases. Irisin attenuates synaptic and memory dysfunction,…”
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Mitochondrial Dysfunction: Pathophysiology and Mitochondria-Targeted Drug Delivery Approaches
Published in Pharmaceutics (30-11-2022)“…Mitochondria are implicated in a wide range of functions apart from ATP generation, and, therefore, constitute one of the most important organelles of cell…”
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Unraveling the Binding Mechanism of Alzheimer's Drugs with Irisin: Spectroscopic, Calorimetric, and Computational Approaches
Published in International journal of molecular sciences (25-05-2022)“…The prevalence of Alzheimer's disease (AD) has been a major health concern for a long time. Despite recent progress, there is still a strong need to develop…”
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Understanding the Modulation of α‑Synuclein Fibrillation by N‑Acetyl Aspartate: A Brain Metabolite
Published in ACS omega (12-03-2024)“…α-Synuclein (α-Syn) fibrillation is a prominent contributor to neuronal deterioration and plays a significant role in the advancement of Parkinson’s Disease…”
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A sustainable design approach of a mega hostel: a study based at NIT, Srinagar, Kashmir, India
Published in Water practice and technology (01-10-2024)“…In a sustainable building design, energy, water and resource optimization are key considerations, along with minimizing impacts on the ecology and environment…”
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Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer’s Disease
Published in ACS omega (23-03-2021)“…This study was aimed to study the interaction between purified irisin and rivastigmine tartrate (RT), a cholinesterase inhibitor used in Alzheimer’s therapy…”
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Recent advancement in therapeutic strategies for Alzheimer's disease: Insights from clinical trials
Published in Ageing research reviews (01-12-2023)“…Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the presence of plaques of amyloid beta and Tau proteins. There is currently…”
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Mycobacterium tuberculosis protein PPE15 (Rv1039c) possesses eukaryote-like SH3 domain that interferes with NADPH Oxidase assembly and Reactive Oxygen Species production
Published in Biochimica et biophysica acta. Molecular cell research (01-04-2024)“…Inhibition of Reactive Oxygen Species (ROS) is one of the strategies that Mycobacterium tuberculosis (Mtb) employs as its defence mechanism. In this study, the…”
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Inhibitory potential of N-acetylaspartate against protein glycation, AGEs formation and aggregation: Implication of brain osmolyte in glycation-related complications
Published in International journal of biological macromolecules (31-07-2023)“…Protein glycation and aggregation have a pivotal role in many diseases including diabetes and neurodegenerative disorders. N-acetyl aspartate (NAA), an…”
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Aggregation of irisin and its prevention by trehalose: A biophysical approach
Published in Journal of molecular structure (05-06-2023)“…•Irisin is a myokine having important role in adipose tissue metabolism, neuronal functioning as well as bone metabolism.•Trehalose prevents aggregation of…”
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Effect of pH on the structure and stability of irisin, a multifunctional protein: Multispectroscopic and molecular dynamics simulation approach
Published in Journal of molecular structure (15-03-2022)“…•Irisin is a potential therapeutic agent to treat metabolic-related diseases and AD.•Effect of pH on the structure and stability of irisin has been measured…”
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Molecular basis of structural stability of Irisin: A combined molecular dynamics simulation and in vitro studies for Urea-induced denaturation
Published in Journal of molecular liquids (15-02-2023)“…•Irisin is a myokine having important role in neuronal functioning, adipose tissue as well as bone metabolism.•Urea-induced conformational changes in irisin…”
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Quantitative Analysis of Land Use Land Cover (LULC) Changes on the Hydrological Behavior of the Jhelum River Basin: North-West Himalayas, Kashmir
Published in Water conservation science and engineering (01-12-2024)“…Land Use and Land Cover (LULC) and its change remains a major factor responsible for altering the overall streamflow characteristics and its hydrological…”
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Reporting effective extraction methodology and chemical characterization of bioactive components of under explored Platycladus orientalis (L.) Franco from semi-arid climate
Published in Natural product research (03-05-2019)“…The bioactive ingredients of many essential oils are complex and difficult to reproduce synthetically. In the present study, the influence of extraction method…”
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Fabrication of NiO coated SiO2 and SiO2 coated NiO for the removal of Pb2+ ions
Published in Chinese chemical letters (01-05-2014)“…We have prepared silica,SiO2coated NiO and NiO coated SiO2by sol-gel method.The physicochemical properties of the desired materials were investigated by…”
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Prevalence and Molecular Diagnosis of Fasciola hepatica in Sheep and Goats in Different Districts of Punjab, Pakistan
Published in Pakistan veterinary journal (01-01-2012)“…A study was conducted to determine the prevalence and molecular diagnosis of fasciolosis in Lohi sheep and Beetal goats in Okara, Sahiwal and Lahore districts…”
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