Search Results - "Waseem, Durdana"
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Bioassays guided isolation of berberine from Berberis lycium and its neuroprotective role in aluminium chloride induced rat model of Alzheimer’s disease combined with insilico molecular docking
Published in PloS one (01-11-2023)“…Objective Berberis lycium is an indigenous plant of Pakistan that is known for its medicinal properties. In the current study, we investigated the…”
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Withametelin: a biologically active withanolide in cancer, inflammation, pain and depression
Published in Saudi pharmaceutical journal (01-12-2020)“…[Display omitted] Withanolides are natural medicinal agents whose safety and therapeutic profiles make them valuable to mankind. Among multiple withanolides,…”
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Polyphenolic characterization and evaluation of multimode antioxidant, cytotoxic, biocompatibility and antimicrobial potential of selected ethno-medicinal plant extracts
Published in Arabian journal of chemistry (01-02-2023)“…Scientific evidence about biological profile of natural products can support their traditional uses. The current work was aimed to assess phytochemical and…”
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Comparative appraisal of in vitro biological profile and in vivo wound healing attributes of bergenin and Bergenia ciliata (Haw.) Sternb
Published in Journal of ethnopharmacology (25-03-2023)“…People of all ages experience injuries, whether mild or severe. The most available option to treat wounds as an alternative to allopathic care in both urban…”
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Dibutylstannanediyl (2Z,2′Z)-bis(4-(benzylamino)-4-oxobut-2-enoate inhibits prostate cancer progression by activating p38 MAPK/PPARα/SMAD4 signaling
Published in Toxicology and applied pharmacology (15-08-2022)“…Organotin (IV) compounds are a focus of research for potential use in cancer chemotherapy. Here, we established anticancer profile of dibutyltin (IV)…”
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Antibacterial potential and synergistic interaction between natural polyphenolic extracts and synthetic antibiotic on clinical isolates
Published in Saudi journal of biological sciences (01-03-2023)“…Emergence of antimicrobial resistance complicates treatment of infections by antibiotics. This has driven research on novel and combination antibacterial…”
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Ousting RAGE in melanoma: A viable therapeutic target?
Published in Seminars in cancer biology (01-04-2018)“…Melanoma remains an important health concern, given the steady increase in incidence and acquisition of resistance to systemic therapies. The receptor for…”
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Structural elucidation and bioassays of newly synthesized pentavalent antimony complexes
Published in Journal of organometallic chemistry (15-11-2017)“…Antimony (V) organometallics (1–5) have been synthesized with general formula [SbR′3(O2CR)2], where R' = phenyl, p-tolyl and O2CR are substituted cinnamates…”
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The triphenyltin carboxylate derivative triphenylstannyl 2-(benzylcarbamoyl)benzoate impedes prostate cancer progression via modulation of Akt/FOXO3a signaling
Published in Toxicology and applied pharmacology (15-08-2020)“…Prostate cancer (PCa) incidence is surging in United States and other parts of the world. Synthetic and natural compounds have been explored as potential…”
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Abstract 688: Triphenylstannyl 2-(benzylcarbamoyl)benzoate (Ch-319) modulates AKT/FOXO3a signaling and inhibits progression of prostate cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Prostate cancer (PCa) is the most commonly diagnosed non-cutaneous malignancy in men in the United States. Moreover, its incidence is predicted to…”
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Implication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis
Published in Journal of molecular neuroscience (01-08-2018)“…Single nucleotide polymorphism in OPRM1 gene is associated with hedonic and reinforcing consequences of opioids. Risk and protective alleles may vary in…”
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Carboxylate derivatives of tributyltin (IV) complexes as anticancer and antileishmanial agents
Published in Daru (04-04-2017)“…Background Tributyltin (IV) compounds are promising candidates for drug development. In the current study, we evaluated in-vitro and in-silico profile of…”
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Synthesis of heteroleptic pentavalent antimonials bearing heterocyclic cinnamate moieties and their biological studies
Published in Inorganica Chimica Acta (01-05-2018)“…[Display omitted] •The Sb(V) complexes (1–6) characterized spectroscopically by FTIR, 1H &13C NMR and single crystal XRD.•Screened for antileishmanial,…”
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Correction to: Implication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis
Published in Journal of molecular neuroscience (01-10-2018)“…The original version of this article is missing the Acknowledgments section…”
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A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence
Published in Computers in biology and medicine (01-10-2014)“…Abstract Single nucleotide polymorphisms (SNPs) both in coding and non-coding regions govern gene functions prompting differential vulnerability to diseases,…”
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In silico transcriptional regulation and functional analysis of dengue shock syndrome associated SNPs in PLCE1 and MICB genes
Published in Functional & integrative genomics (01-05-2016)“…Single nucleotide polymorphisms (SNPs) in PLCE1 and MICB genes increase risk for the development of dengue shock syndrome (DSS). We used Bioinformatics tools…”
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A molecular prospective provides new insights into implication ofPDYNandOPRK1genes in alcohol dependence
Published in Computers in biology and medicine (01-10-2014)“…Single nucleotide polymorphisms (SNPs) both in coding and non-coding regions govern gene functions prompting differential vulnerability to diseases,…”
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Phytochemical Analysis and Antioxidant Potential of Ficus Benghalensis L
Published in Journal of bioresource management (01-07-2017)“…Genus Ficus belongs to family Moraceae having 40 genera and over 1000 species worldwide. Different methods have been used for phytochemical screening of…”
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EVALUATION OF DRUG USE INDICATORS FOR NON-COMMUNICABLE DISEASES IN PAKISTAN
Published in Acta Poloniae pharmaceutica (01-05-2016)“…Irrational drug use practices are a burden to healthcare facilities. Poor prescribing practices affect the overall management and cost of treatment of…”
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