Search Results - "Wasén, Caroline"

Gut Microbiome in Progressive Multiple Sclerosis by Cox, Laura M., Maghzi, Amir Hadi, Liu, Shirong, Tankou, Stephanie K., Dhang, Fyonn H., Willocq, Valerie, Song, Anya, Wasén, Caroline, Tauhid, Shahamat, Chu, Renxin, Anderson, Mark C., De Jager, Philip L., Polgar‐Turcsanyi, Mariann, Healy, Brian C., Glanz, Bonnie I., Bakshi, Rohit, Chitnis, Tanuja, Weiner, Howard L.

“…Objective This study was undertaken to investigate the gut microbiome in progressive multiple sclerosis (MS) and how it relates to clinical disease. Methods We…”
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Insights into the Mechanism for Vertical Graphene Growth by Plasma-Enhanced Chemical Vapor Deposition by Sun, Jie, Rattanasawatesun, Tanupong, Tang, Penghao, Bi, Zhaoxia, Pandit, Santosh, Lam, Lisa, Wasén, Caroline, Erlandsson, Malin, Bokarewa, Maria, Dong, Jichen, Ding, Feng, Xiong, Fangzhu, Mijakovic, Ivan

“…Vertically oriented graphene (VG) has attracted attention for years, but the growth mechanism is still not fully revealed. The electric field may play a role,…”
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Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice by Wieg, Laura, Ciola, Jason C, Wasén, Caroline C, Gaba, Fidelia, Colletti, Brianna R, Schroeder, Maren K, Hinshaw, Robert G, Ekwudo, Millicent N, Holtzman, David M, Saito, Takashi, Sasaguri, Hiroki, Saido, Takaomi C, Cox, Laura M, Lemere, Cynthia A

“…Cosmic radiation experienced during space travel may increase the risk of cognitive impairment. While simulated galactic cosmic radiation (GCRsim) has led to…”
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Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models by Wasén, Caroline, Beauchamp, Leah C., Vincentini, Julia, Li, Shuqi, LeServe, Danielle S., Gauthier, Christian, Lopes, Juliana R., Moreira, Thais G., Ekwudo, Millicent N., Yin, Zhuoran, da Silva, Patrick, Krishnan, Rajesh K., Butovsky, Oleg, Cox, Laura M., Weiner, Howard L.

“…The gut microbiota and microglia play critical roles in Alzheimer’s disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β…”
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Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis by Andersson, Karin M. E., Wasén, Caroline, Juzokaite, Lina, Leifsdottir, Lovisa, Erlandsson, Malin C., Silfverswärd, Sofia T., Stokowska, Anna, Pekna, Marcela, Pekny, Milos, Olmarker, Kjell, Heckemann, Rolf A., Kalm, Marie, Bokarewa, Maria I.

“…Rheumatoid arthritis (RA) is an inflammatory joint disease with a neurological component including depression, cognitive deficits, and pain, which…”
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IGF1R signalling is a guardian of self-tolerance restricting autoantibody production by Erlandsson, Malin C., Erdogan, Seval, Wasén, Caroline, Andersson, Karin M. E., Silfverswärd, Sofia T., Pullerits, Rille, Bemark, Mats, Bokarewa, Maria I.

“…Objective Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these…”
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Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis by Erlandsson, Malin C, Lyngfelt, Lovisa, Åberg, N David, Wasén, Caroline, Espino, Rachelle A, Silfverswärd, Sofia Töyrä, Nadali, Mitra, Jood, Katharina, Andersson, Karin M E, Pullerits, Rille, Bokarewa, Maria I

“…Since low insulin-like growth factor (IGF) 1 is often linked to inflammation, we analyze whether serum levels of IGF1 are associated with cardiovascular…”
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Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8 + T Cells in Rheumatoid Arthritis by Wasén, Caroline, Ospelt, Caroline, Camponeschi, Alessandro, Erlandsson, Malin C, Andersson, Karin M E, Silfverswärd, Sofia Töyrä, Gay, Steffen, Bokarewa, Maria I

“…Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA). In this study, we assess if smoking changed the epigenetic control over CD8 T…”
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Cohesin-Mediated Chromatin Interactions and Autoimmunity by Chandrasekaran, Venkataragavan, Oparina, Nina, Garcia-Bonete, Maria-Jose, Wasén, Caroline, Erlandsson, Malin C, Malmhäll-Bah, Eric, Andersson, Karin M E, Jensen, Maja, Silfverswärd, Sofia T, Katona, Gergely, Bokarewa, Maria I

“…Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions…”
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Dietary protein modulates intestinal dendritic cells to establish mucosal homeostasis by Moreira, Thais G., Cox, Laura M., Da Silva, Patrick, Mangani, Davide, De Oliveira, Marilia G., Escobar, Giulia, Lanser, Toby B., Murphy, Liam, Lobo, Eduardo.L.C., Milstein, Omer, Gauthier, Christian D., Clara Guimarāes, Ana, Schwerdtfeger, Luke, Ekwudo, Mellicient N., Wasén, Caroline, Liu, Shirong, Menezes, Gustavo B., Ferreira, Enio, Gabriely, Galina, Anderson, Ana C., Faria, Ana Maria C., Rezende, Rafael M., Weiner, Howard L.

“…Dietary proteins are taken up by intestinal dendritic cells (DCs), cleaved into peptides, loaded to major histocompatibility complexes, and presented to T…”
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Smoking activates cytotoxic CD8+ T cells and causes survivin release in rheumatoid arthritis by Wasén, Caroline, Turkkila, Minna, Bossios, Apostolos, Erlandsson, Malin, Andersson, Karin M, Ekerljung, Linda, Malmhäll, Carina, Brisslert, Mikael, Töyrä Silfverswärd, Sofia, Lundbäck, Bo, Bokarewa, Maria I

“…Abstract CD8+ T cells have an emerging role in RA. Resent research indicates a causal relationship between the non-exhausted state of CD8+ T cells, defined by…”
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Smoking Is Associated With Low Levels of Soluble PD-L1 in Rheumatoid Arthritis by Wasén, Caroline, Erlandsson, Malin C, Bossios, Apostolos, Ekerljung, Linda, Malmhäll, Carina, Töyrä Silfverswärd, Sofia, Pullerits, Rille, Lundbäck, Bo, Bokarewa, Maria I

“…Smoking is a risk factor for developing rheumatoid arthritis (RA), but the mechanism remains uncertain. We previously demonstrated that smoking lowers the T…”
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Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination by Svensson, Mattias N.D., Andersson, Karin M. E., Wasén, Caroline, Erlandsson, Malin C., Nurkkala-Karlsson, Merja, Jonsson, Ing-Marie, Brisslert, Mikael, Bemark, Mats, Bokarewa, Maria I.

“…Switched antibody classes are important for efficient immune responses. Aberrant antibody production to otherwise harmless antigens may result in autoimmunity…”
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The emerging role of the microbiome in Alzheimer's disease by Wasén, Caroline, Simonsen, Ella, Ekwudo, Millicent N, Profant, Martin R, Cox, Laura M

“…Alzheimer's disease (AD) is the most prevalent form of dementia and can be influenced by genetic and environmental factors. Recent studies suggest that the…”
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The gut microbiota is an emerging target for improving brain health during ageing by Boehme, Marcus, Guzzetta, Katherine Elizabeth, Wasén, Caroline, Cox, Laura Michelle

“…The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host throughout lifespan, including through its ability to impact brain…”
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Mannose is an insulin-regulated metabolite reflecting whole-body insulin sensitivity in man by Ferrannini, E., Bokarewa, M., Brembeck, P., Baboota, R., Hedjazifar, S., Andersson, K., Baldi, S., Campi, B., Muscelli, E., Saba, A., Sterner, I., Wasen, C., Smith, U.

“…Mannose is a glucose-associated serum metabolite mainly released by the liver. Recent studies have shown several unexpected pleiotropic effects of mannose…”
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Survivin in autoimmune diseases by Gravina, G, Wasen, C, Garcia-Bonete, M.J, Turkkila, M, Erlandsson, M.C, Töyrä Silfverswärd, S, Brisslert, M, Pullerits, R, Andersson, K.M, Katona, G, Bokarewa, M.I

“…Abstract Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-RNA biogenesis. It is an established marker of…”
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Downregulation of toll-like receptor 4 and IL-6 following irradiation of the rat urinary bladder by Giglio, D, Wasén, C, Mölne, J, Suchy, D, Swanpalmer, J, Jabonero Valbuena, J, Tobin, G, Ny, L

“…Summary The pathophysiology behind radiation cystitis is poorly understood. Here we investigated whether bladder irradiation affects the immune system of the…”
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Epidermal growth factor receptor function in the human urothelium by Wasén, C., Ekstrand, M., Levin, M., Giglio, D.

“…Purpose Epidermal growth factor receptor (EGFr)-targeted therapy may be used in subgroups of patients with urinary bladder cancer. Here we assessed the role of…”
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Proliferation of the human urothelium is induced by atypical β1 -adrenoceptors by Winder, M, Wasén, C, Aronsson, P, Giglio, D

“…We wanted to assess whether β-adrenoceptors mediate proliferation in the normal and malignant urothelial cell lines UROtsa and T24, respectively. Urothelial…”
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