Search Results - "Warth, Benedikt"

Drug–Exposome Interactions: The Next Frontier in Precision Medicine by Pristner, Manuel, Warth, Benedikt

“…Drug–drug interactions are a known concern during medical treatment. However, in addition to therapeutic drugs, humans are exposed to thousands of environment-…”
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METLIN MS2 molecular standards database: a broad chemical and biological resource by Xue, Jingchuan, Guijas, Carlos, Benton, H. Paul, Warth, Benedikt, Siuzdak, Gary

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Longitudinal assessment of mycotoxin co-exposures in exclusively breastfed infants by Braun, Dominik, Schernhammer, Eva, Marko, Doris, Warth, Benedikt

“…[Display omitted] •Mycotoxin excretion patterns were investigated the first 211 days after delivery.•Low chronic mycotoxin background contamination revealed…”
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Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online by Forsberg, Erica M, Huan, Tao, Rinehart, Duane, Benton, H Paul, Warth, Benedikt, Hilmers, Brian, Siuzdak, Gary

“…This protocol describes XCMS Online, a web-based systems biology platform for processing of metabolomics data, pathway mapping and integration with genomics…”
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Next-generation biomonitoring of the early-life chemical exposome in neonatal and infant development by Jamnik, Thomas, Flasch, Mira, Braun, Dominik, Fareed, Yasmin, Wasinger, Daniel, Seki, David, Berry, David, Berger, Angelika, Wisgrill, Lukas, Warth, Benedikt

“…Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures…”
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Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization by Pereira, Fátima C., Wasmund, Kenneth, Cobankovic, Iva, Jehmlich, Nico, Herbold, Craig W., Lee, Kang Soo, Sziranyi, Barbara, Vesely, Cornelia, Decker, Thomas, Stocker, Roman, Warth, Benedikt, von Bergen, Martin, Wagner, Michael, Berry, David

“…Many intestinal pathogens, including Clostridioides difficile , use mucus-derived sugars as crucial nutrients in the gut. Commensals that compete with…”
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METLIN: A Technology Platform for Identifying Knowns and Unknowns by Guijas, Carlos, Montenegro-Burke, J. Rafael, Domingo-Almenara, Xavier, Palermo, Amelia, Warth, Benedikt, Hermann, Gerrit, Koellensperger, Gunda, Huan, Tao, Uritboonthai, Winnie, Aisporna, Aries E, Wolan, Dennis W, Spilker, Mary E, Benton, H. Paul, Siuzdak, Gary

“…METLIN originated as a database to characterize known metabolites and has since expanded into a technology platform for the identification of known and unknown…”
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A Generic Liquid Chromatography−Tandem Mass Spectrometry Exposome Method for the Determination of Xenoestrogens in Biological Matrices by Preindl, Karin, Braun, Dominik, Aichinger, Georg, Sieri, Sabina, Fang, Mingliang, Marko, Doris, Warth, Benedikt

“…We are constantly exposed to a variety of environmental contaminants and hormones, including those mimicking endogenous estrogens. These highly heterogeneous…”
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Quantitation of Mycotoxins in Food and Feed from Burkina Faso and Mozambique Using a Modern LC-MS/MS Multitoxin Method by Warth, Benedikt, Parich, Alexandra, Atehnkeng, Joseph, Bandyopadhyay, Ranajit, Schuhmacher, Rainer, Sulyok, Michael, Krska, Rudolf

“…In this study an LC-MS/MS multitoxin method covering a total of 247 fungal and bacterial metabolites was applied to the analysis of different foods and…”
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A fiber-deprived diet disturbs the fine-scale spatial architecture of the murine colon microbiome by Riva, Alessandra, Kuzyk, Orest, Forsberg, Erica, Siuzdak, Gary, Pfann, Carina, Herbold, Craig, Daims, Holger, Loy, Alexander, Warth, Benedikt, Berry, David

“…Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains…”
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Early-life chemical exposome and gut microbiome development: African research perspectives within a global environmental health context by Ayeni, Kolawole I, Berry, David, Wisgrill, Lukas, Warth, Benedikt, Ezekiel, Chibundu N

“…The gut microbiome of neonates, infants, and toddlers (NITs) is very dynamic, and only begins to stabilize towards the third year of life. Within this period,…”
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Insights into the early-life chemical exposome of Nigerian infants and potential correlations with the developing gut microbiome by Oesterle, Ian, Ayeni, Kolawole I., Ezekiel, Chibundu N., Berry, David, Rompel, Annette, Warth, Benedikt

“…[Display omitted] •Suspect screening of exposure biomarkers in human breast milk and infant stool.•542 features in breast milk and 864 in stool were identified…”
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Elucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells by Flasch, Mira, Bueschl, Christoph, Del Favero, Giorgia, Adam, Gerhard, Schuhmacher, Rainer, Marko, Doris, Warth, Benedikt

“…[Display omitted] •The mycoestrogen zearalenone was significantly metabolized by phase I biotransformation in MCF-7 cells to more estrogenic…”
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Mycotoxin exposure biomonitoring in breastfed and non-exclusively breastfed Nigerian children by Ezekiel, Chibundu N., Abia, Wilfred A., Braun, Dominik, Šarkanj, Bojan, Ayeni, Kolawole I., Oyedele, Oluwawapelumi A., Michael-Chikezie, Emmanuel C., Ezekiel, Victoria C., Mark, Beatrice N., Ahuchaogu, Chinonso P., Krska, Rudolf, Sulyok, Michael, Turner, Paul C., Warth, Benedikt

“…A multi-specimen, multi-mycotoxin approach involving ultra-sensitive LC-MS/MS analysis of breast milk, complementary food and urine was applied to examine…”
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In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship by Crudo, Francesco, Aichinger, Georg, Mihajlovic, Jovana, Varga, Elisabeth, Dellafiora, Luca, Warth, Benedikt, Dall’Asta, Chiara, Berry, David, Marko, Doris

“…The human gut microbiota plays an important role in the maintenance of human health. Factors able to modify its composition might predispose the host to the…”
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Combinatory effects of cereulide and deoxynivalenol on in vitro cell viability and inflammation of human Caco-2 cells by Beisl, Julia, Pahlke, Gudrun, Abeln, Helen, Ehling-Schulz, Monika, Del Favero, Giorgia, Varga, Elisabeth, Warth, Benedikt, Sulyok, Michael, Abia, Wilfred, Ezekiel, Chibundu N., Marko, Doris

“…Deoxynivalenol (DON), one of the most abundant mycotoxins in cereal products, was recently detected with other mycotoxins and the emetic bacterial toxin…”
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Mycotoxin exposure in rural residents in northern Nigeria: A pilot study using multi-urinary biomarkers by Ezekiel, Chibundu N., Warth, Benedikt, Ogara, Isaac M., Abia, Wilfred A., Ezekiel, Victoria C., Atehnkeng, Joseph, Sulyok, Michael, Turner, Paul C., Tayo, Grace O., Krska, Rudolf, Bandyopadhyay, Ranajit

“…A pilot, cross-sectional, correlational study was conducted in eight rural communities in northern Nigeria to investigate mycotoxin exposures in 120 volunteers…”
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Multiple mycotoxin exposure determined by urinary biomarkers in rural subsistence farmers in the former Transkei, South Africa by Shephard, Gordon S., Burger, Hester-Mari, Gambacorta, Lucia, Gong, Yun Yun, Krska, Rudolf, Rheeder, John P., Solfrizzo, Michele, Srey, Chou, Sulyok, Michael, Visconti, Angelo, Warth, Benedikt, van der Westhuizen, Liana

“…•Demonstrated the use of multi-biomarker methods in measuring exposure in communities in which dietary analysis is difficult.•This is the first finding of…”
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Exposure to Mycotoxin-Mixtures via Breast Milk: An Ultra-Sensitive LC-MS/MS Biomonitoring Approach by Braun, Dominik, Ezekiel, Chibundu N, Marko, Doris, Warth, Benedikt

“…Exposure to natural food contaminants during infancy may influence health consequences later in life. Hence, breast milk may serve as a vehicle to transport…”
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Bio-monitoring of mycotoxin exposure in Cameroon using a urinary multi-biomarker approach by Abia, Wilfred A., Warth, Benedikt, Sulyok, Michael, Krska, Rudolf, Tchana, Angele, Njobeh, Patrick B., Turner, Paul C., Kouanfack, Charles, Eyongetah, Mbu, Dutton, Mike, Moundipa, Paul F.

“…•Frequent exposure to a diverse variety of mycotoxins amongst Cameroonians.•Exposure to more than one mycotoxin in some individuals.•Detection of four and five…”
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