Search Results - "Wartel, Morgane"

Motor-driven intracellular transport powers bacterial gliding motility by Sun, Mingzhai, Wartel, Morgane, Cascales, Eric, Shaevitz, Joshua W, Mignot, Tâm

“…Protein-directed intracellular transport has not been observed in bacteria despite the existence of dynamic protein localization and a complex cytoskeleton…”
Get full text

Human Brain Organoids as Models for Central Nervous System Viral Infection by Depla, Josse A, Mulder, Lance A, de Sá, Renata Vieira, Wartel, Morgane, Sridhar, Adithya, Evers, Melvin M, Wolthers, Katja C, Pajkrt, Dasja

“…Pathogenesis of viral infections of the central nervous system (CNS) is poorly understood, and this is partly due to the limitations of currently used…”
Get full text

Phenotype inference in an Escherichia coli strain panel by Galardini, Marco, Koumoutsi, Alexandra, Herrera-Dominguez, Lucia, Cordero Varela, Juan Antonio, Telzerow, Anja, Wagih, Omar, Wartel, Morgane, Clermont, Olivier, Denamur, Erick, Typas, Athanasios, Beltrao, Pedro

“…Understanding how genetic variation contributes to phenotypic differences is a fundamental question in biology. Combining high-throughput gene function assays…”
Get full text

LinQURE: A novel AAV gene silencing platform that supports multi-transcript targeting for complex disorders by Bočkaj, Irena, Moreno Garcia, Anna, de Miguel Herraiz, Pablo, Keskin, Sonay, Zancanella, Vanessa, Acar Broekmans, Şeyda, Vallès, Astrid, Liu, Ying Poi, Evers, Melvin, Wartel, Morgane

“…Given that numerous genetic disorders, driven by diverse pathogenic mechanisms, may be amenable to recombinant adeno-associated virus (rAAV)-delivered gene…”
Get full text

An evolutionary link between capsular biogenesis and surface motility in bacteria by Agrebi, Rym, Wartel, Morgane, Brochier-Armanet, Céline, Mignot, Tâm

“…Mignot and colleagues present an evolutionary scenario to explain the emergence of the two distinct machines — the Agl–Glt and Agl–Nfs complexes — that are…”
Get full text

Emergence and modular evolution of a novel motility machinery in bacteria by Luciano, Jennifer, Agrebi, Rym, Le Gall, Anne Valérie, Wartel, Morgane, Fiegna, Francesca, Ducret, Adrien, Brochier-Armanet, Céline, Mignot, Tâm

“…Bacteria glide across solid surfaces by mechanisms that have remained largely mysterious despite decades of research. In the deltaproteobacterium Myxococcus…”
Get full text

A tool named Iris for versatile high-throughput phenotyping in microorganisms by Kritikos, George, Banzhaf, Manuel, Herrera-Dominguez, Lucia, Koumoutsi, Alexandra, Wartel, Morgane, Zietek, Matylda, Typas, Athanasios

“…Advances in our ability to systematically introduce and track controlled genetic variance in microorganisms have, in the past decade, fuelled high-throughput…”
Get full text

A novel AAV9-dual microRNA-vector targeting GRIK2 in the hippocampus as a treatment for mesial temporal lobe epilepsy by Baudouin, Stéphane J., Giles, April R., Pearson, Nick, Deforges, Severine, He, Chenxia, Boileau, Céline, Partouche, Nicolas, Borta, Andreas, Gautron, Justine, Wartel, Morgane, Bočkaj, Irena, Scavarda, Didier, Bartolomei, Fabrice, Penchet, Guillaume, Aupy, Jérôme, Sims, Jennifer, Smith, Jared, Mercer, Andrew, Danos, Olivier, Mulle, Christophe, Crépel, Valérie, Porter, Richard

“…Mesial temporal lobe epilepsy (mTLE) is the most prevalent type of epilepsy in adults. First and subsequent generations of anti-epileptic therapy regimens fail…”
Get full text

A versatile class of cell surface directional motors gives rise to gliding motility and sporulation in Myxococcus xanthus by Wartel, Morgane, Ducret, Adrien, Thutupalli, Shashi, Czerwinski, Fabian, Le Gall, Anne-Valérie, Mauriello, Emilia M F, Bergam, Ptissam, Brun, Yves V, Shaevitz, Joshua, Mignot, Tâm

“…Eukaryotic cells utilize an arsenal of processive transport systems to deliver macromolecules to specific subcellular sites. In prokaryotes, such transport…”
Get full text

Functional Intercellular Transmission of miHTT via Extracellular Vesicles: An In Vitro Proof-of-Mechanism Study by Morais, Roberto D V S, Sogorb-González, Marina, Bar, Citlali, Timmer, Nikki C, Van der Bent, M Leontien, Wartel, Morgane, Vallès, Astrid

“…Huntington's disease (HD) is a fatal neurodegenerative disorder caused by GAG expansion in exon 1 of the huntingtin ( ) gene. AAV5-miHTT is an adeno-associated…”
Get full text

Preclinical Proof-of-concept of a Novel AAV9-microRNA based Targeting of GRIK2 for the Treatment of Temporal Lobe Epilepsy (S44.001) by Pearson, Nick, Baudouin, Stephane, Wartel, Morgane, Keskin, Sonay, Danos, Olivier, Mulle, Christophe, Partouche, Nicolas, Crépel, Valérie, Borta, Andreas, Porter, Richard

“…Abstract only…”
Get full text

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli by Banzhaf, Manuel, Yau, Hamish CL, Verheul, Jolanda, Lodge, Adam, Kritikos, George, Mateus, André, Cordier, Baptiste, Hov, Ann Kristin, Stein, Frank, Wartel, Morgane, Pazos, Manuel, Solovyova, Alexandra S, Breukink, Eefjan, van Teeffelen, Sven, Savitski, Mikhail M, den Blaauwen, Tanneke, Typas, Athanasios, Vollmer, Waldemar

“…The peptidoglycan (PG) sacculus provides bacteria with the mechanical strength to maintain cell shape and resist osmotic stress. Enlargement of the mesh‐like…”
Get full text

Fungal diversity in anoxic-sulfidic sediments in a mangrove soil by Arfi, Yonathan, Marchand, Cyril, Wartel, Morgane, Record, Eric

“…Fungi are important actors in the ecological processes occurring in mangroves and are thought to play a role in organic matter decomposition pathways, despite…”
Get full text

Erratum: An evolutionary link between capsular biogenesis and surface motility in bacteria by Agrebi, Rym, Wartel, Morgane, Brochier-Armanet, Céline, Mignot, Tâm

“…Nature Reviews Microbiology 13, 318–326 (2015) In the above article, the credit lines for Figure 2a,d and Figure 4 were incorrect and have been corrected…”
Get full text

An evolutionary link between capsular biogenesis and surface motility in bacteria by Agrebi, Rym, Wartel, Morgane, Brochier-Armanet, Celine, Mignot, Tam

Get full text

A Versatile Class of Cell Surface Directional Motors Gives Rise to Gliding Motility and Sporulation in Myxococcus xanthus: e1001728 by Wartel, Morgane, Ducret, Adrien, Thutupalli, Shashi, Czerwinski, Fabian, Gall, Anne-Valérie Le, Mauriello, Emilia MF, Bergam, Ptissam, Brun, Yves V, Shaevitz, Joshua, Mignot, Tâm

“…Eukaryotic cells utilize an arsenal of processive transport systems to deliver macromolecules to specific subcellular sites. In prokaryotes, such transport…”
Get full text

Emergence and Modular Evolution of a Novel Motility Machinery in Bacteria: e1002268 by Luciano, Jennifer, Agrebi, Rym, Gall, Anne ValérieLe, Wartel, Morgane, Fiegna, Francesca, Ducret, Adrien, Brochier-Armanet, Céline, Mignot, Tâm

“…Bacteria glide across solid surfaces by mechanisms that have remained largely mysterious despite decades of research. In the deltaproteobacterium Myxococcus…”
Get full text