Search Results - "Warsh, J"
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In vivo evidence for greater amphetamine-induced dopamine release in pathological gambling: a positron emission tomography study with [11C]-(+)-PHNO
Published in Molecular psychiatry (01-12-2014)“…Drug addiction has been associated with deficits in mesostriatal dopamine (DA) function, but whether this state extends to behavioral addictions such as…”
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Hydrogel particles improve detection of SARS-CoV-2 RNA from multiple sample types
Published in Scientific reports (30-12-2020)“…Here we present a rapid and versatile method for capturing and concentrating SARS-CoV-2 from contrived transport medium and saliva samples using…”
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Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: Relevance to the pathophysiology of bipolar disorder
Published in Brain research (23-06-2013)“…Abstract Recent findings implicate the calcium-permeable transient receptor potential (TRP) melastatin subtype 2 (TRPM2) and canonical subtype 3 (TRPC3)…”
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Brain serotonin transporter binding in non-depressed patients with Parkinson's disease
Published in European journal of neurology (01-05-2007)“…Early post‐mortem data suggest that damage to brain serotonin neurones might play a role in some features (e.g., depression) of Parkinson's disease (PD)…”
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Are school zones effective? An examination of motor vehicle versus child pedestrian crashes near schools
Published in Injury prevention (01-08-2009)“…To analyse the relationships between factors related to school location and motor vehicle versus child pedestrian collisions. Data on all police-reported motor…”
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Cytoprotection by lithium and valproate varies between cell types and cellular stresses
Published in European journal of pharmacology (06-06-2006)“…Despite much evidence that lithium and valproate, two commonly used mood stabilizers, exhibit neuroprotective properties against an array of insults, the…”
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Increased bcl-2 Protein Levels in Rat Primary Astrocyte Culture Following Chronic Lithium Treatment
Published in Iranian journal of medical sciences (01-09-2013)“…B cell CLL/lymphoma 2 protein, bcl-2, is an important anti-apoptotic factor that has been implicated in lithium's neuroprotective effect. However, most studies…”
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Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder
Published in Bipolar disorders (01-03-2012)“…Roedding AS, Gao AF, Au‐Yeung W, Scarcelli T, Li PP, Warsh JJ. Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar…”
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TRPM2 variants and bipolar disorder risk: confirmation in a family-based association study
Published in Bipolar disorders (01-02-2009)“…Objective: Recent case‐control studies implicate the transient receptor potential melastatin 2 (TRPM2) channel in conferring risk for bipolar disorder (BD),…”
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10
Inhibition of glycogen synthase kinase-3 enhances the differentiation and reduces the proliferation of adult human olfactory epithelium neural precursors
Published in Experimental cell research (10-09-2011)“…The olfactory epithelium (OE) contains neural precursor cells which can be easily harvested from a minimally invasive nasal biopsy, making them a valuable cell…”
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High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder
Published in The American journal of psychiatry (01-07-1997)“…OBJECTIVE: Higher basal concentrations of intracellular calcium Ca2+ in platelets and lymphocytes from subjects with bipolar affective disorder than in…”
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Differential alteration of phospholipase A2 activities in brain of patients with schizophrenia
Published in Brain research (13-03-1999)“…We recently reported that the activity of a calcium-independent subtype of phospholipase A2 is increased in blood of patients with schizophrenia. The present…”
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Altered cAMP‐dependent protein kinase subunit immunolabeling in post‐mortem brain from patients with bipolar affective disorder
Published in Journal of neurochemistry (01-02-2003)“…Previous findings of reduced [3H]cAMP binding and increased activities of cAMP‐dependent protein kinase (PKA) in discrete post‐mortem brain regions from…”
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Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-01-2006)“…Disturbed intracellular calcium (Ca2+) homeostasis has been implicated in bipolar disorder (BD). Reduced mRNA levels of the transient receptor potential Ca2+…”
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15
TRPC3 protein is expressed across the lifespan in human prefrontal cortex and cerebellum
Published in Brain research (13-03-2009)“…Abstract The canonical transient receptor potential type 3 (TRPC3) channel is a non-selective, voltage-independent cation channel that is expressed in both…”
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16
Chronic Lithium Treatment Attenuates Intracellular Calcium Mobilization
Published in Neuropsychopharmacology (New York, N.Y.) (01-04-2004)“…Elevated basal intracellular calcium (Ca(2+)) levels ([Ca(2+)](B)) in B lymphoblast cell lines (BLCLs) from bipolar I disorder (BD-I) patients implicate…”
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CACNA1C SNP rs1006737 associates with bipolar I disorder independent of the Bcl-2 SNP rs956572 variant and its associated effect on intracellular calcium homeostasis
Published in The world journal of biological psychiatry (02-10-2016)“…Objectives. Intracellular calcium (Ca 2+ ) dyshomeostasis (ICDH) has been implicated in bipolar disorder (BD) pathophysiology. We previously showed that SNP…”
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Chronic LiCl pretreatment suppresses thrombin-stimulated intracellular calcium mobilization through TRPC3 in astroglioma cells
Published in Bipolar disorders (01-11-2016)“…Objectives Transient receptor potential canonical type 3 (TRPC3) channels are activated in B lymphoblast cell lines from patients with bipolar disorder (BD),…”
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Increased Cyclic AMP‐Dependent Protein Kinase Activity in Postmortem Brain from Patients with Bipolar Affective Disorder
Published in Journal of neurochemistry (01-10-1999)“…: Previous observations of reduced [3H]cyclic AMP binding in postmortem brainregions frombipolar affective disorder subjects imply cyclic AMP‐dependent…”
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Role of intracellular calcium signaling in the pathophysiology and pharmacotherapy of bipolar disorder: current status
Published in Clinical neuroscience research (01-12-2004)“…Evidence implicating disturbances of intracellular Ca 2+ homeostasis has continued to accumulate, with a recent burst of new observations obtained using…”
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