Search Results - "Warren, Simon"

Re-Thinking the “Problem” in Inquiry-Based Pedagogies through Exemplarity and World-Oriented by Warren, Simon

“…This paper conducts a theoretical exploration of the inquiry-problem in problem-oriented pedagogies. Specifically, the article draws on a critical reflection…”
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Utility of sequencing for ATP6AP1 and ATP6AP2 to distinguish between atypical granular cell tumor with junctional component and melanoma by Warren, Simon J, Alomari, Ahmed K

“…Granular cell tumor (GCT) is a S100+ neoplasm with atypical and malignant variants. Similar to melanocytic neoplasms, the tumors make nests and can have…”
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Detection of driver mutations in BRAF can aid in diagnosis and early treatment of dedifferentiated metastatic melanoma by Alrabadi, Nasr, Gibson, Natasha, Curless, Kendra, Cheng, Liang, Kuhar, Matthew, Chen, Shaoxiong, Warren, Simon J. P., Alomari, Ahmed K.

“…Dedifferentiated metastatic melanoma can pose a significant diagnostic challenge, especially if the history of primary melanoma is not known or is remote. BRAF…”
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Histopathologic, genomic, transcriptomic, and functional characteristics of eight melanocytic tumors with BRAF fusions showing stronger MAPK pathway activation compared to BRAF V600E tumors by Li, Aofei, Warren, Simon J., Umphress, Brandon A., Alomari, Ahmed K.

“…Background Activating BRAF gene alterations are central to melanocytic tumor pathogenesis. A small, emerging subset of melanocytic tumors driven by BRAF…”
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Central and Eastern Europe in Academic Internationalization: Peripherality, Neoliberalism, and Knowledge Production by Starnawski, Marcin, Warren, Simon

“…The article reflects on knowledge production in the context of research internationalization, seen as an aspect of a broader trend in the changing higher…”
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Methodology of Metal Criticality Determination by Graedel, T. E, Barr, Rachel, Chandler, Chelsea, Chase, Thomas, Choi, Joanne, Christoffersen, Lee, Friedlander, Elizabeth, Henly, Claire, Jun, Christine, Nassar, Nedal T, Schechner, Daniel, Warren, Simon, Yang, Man-yu, Zhu, Charles

“…A comprehensive methodology has been created to quantify the degree of criticality of the metals of the periodic table. In this paper, we present and discuss…”
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BNT162b2 vaccine uptake and effectiveness in UK healthcare workers – a single centre cohort study by Azamgarhi, Tariq, Hodgkinson, Michelle, Shah, Ashik, Skinner, John A., Hauptmannova, Iva, Briggs, Tim W. R., Warren, Simon

“…In this single centre cohort study we assessed BNT162B2 vaccine uptake and effectiveness among UK healthcare workers (HCWs) during a time of high community…”
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MAP2K1-mutated melanocytic tumors have reproducible histopathologic features and share similarities with melanocytic tumors with BRAF V600E mutations by Alomari, Ahmed K, Harms, Paul W, Andea, Aleodor A, Warren, Simon J

“…Melanocytic tumors driven by MAP2K1 in-frame deletions are among the most recently described class of melanocytic neoplasms. The reported range of diagnoses…”
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Risk factors for recurrent infection in the surgical treatment of infected massive endoprostheses implanted for musculoskeletal tumours by Azamgarhi, Tariq, Warren, Simon, Aston, Will, Pollock, Rob, Gerrand, Craig

“…Infection is a devastating complication of endoprosthetic replacement (EPR) in orthopaedic oncology. Surgical treatments include debridement and/or one- or…”
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Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers by Jacobs, Michael, Dr, Aarons, Emma, FRCPath, Bhagani, Sanjay, FRCP, Buchanan, Ruaridh, MRCP, Cropley, Ian, FRCP, Hopkins, Susan, FRCP, Lester, Rebecca, MRCP, Martin, Daniel, FRCA, Marshall, Neal, MRPharmS, Mepham, Stephen, FRCPath, Warren, Simon, FRCPath, Rodger, Alison, FRCP

“…Summary Background Although a few international health-care workers who have assisted in the current Ebola outbreak in west Africa have been medically…”
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Criticality of the Geological Copper Family by Nassar, Nedal T, Barr, Rachel, Browning, Matthew, Diao, Zhouwei, Friedlander, Elizabeth, Harper, E. M, Henly, Claire, Kavlak, Goksin, Kwatra, Sameer, Jun, Christine, Warren, Simon, Yang, Man-Yu, Graedel, T. E

“…Because modern technology depends on reliable supplies of a wide variety of materials, and because of increasing concern about those supplies, a comprehensive…”
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Anticipation skill and susceptibility to deceptive movement by Jackson, Robin C., Warren, Simon, Abernethy, Bruce

“…The ability to detect deceptive movement was examined in skilled and novice rugby players. Participants (14 per group) attempted to predict direction change…”
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Gamma scintigraphic pulmonary deposition study of glycopyrronium/formoterol metered dose inhaler formulated using co-suspension delivery technology by Taylor, Glyn, Warren, Simon, Dwivedi, Sarvajna, Sommerville, Mark, Mello, Lauren, Orevillo, Chad, Maes, Andrea, Martin, Ubaldo J., Usmani, Omar S.

“…This gamma scintigraphy imaging study was the first to assess pulmonary and extrathoracic deposition and regional lung deposition patterns of a radiolabelled…”
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CD8‐positive lymphomatoid papulosis (type D): Some lesions may lack CD30 expression and overlap histologically with mycosis fungoides by Simo, Olivia C., Warren, Simon J., Mark, Lawrence, Hoffmann, Kristin, Alomari, Ahmed K.

“…Background CD8+ lymphomatoid papulosis is frequently indistinguishable histopathologically from primary cutaneous aggressive epidermotropic CD8+ T‐cell…”
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Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT by Scarborough, Matthew, Li, Ho Kwong, Rombach, Ines, Zambellas, Rhea, Walker, A Sarah, McNally, Martin, Atkins, Bridget, Kümin, Michelle, Lipsky, Benjamin A, Hughes, Harriet, Bose, Deepa, Warren, Simon, Mack, Damien, Folb, Jonathan, Moore, Elinor, Jenkins, Neil, Hopkins, Susan, Seaton, R Andrew, Hemsley, Carolyn, Sandoe, Jonathan, Aggarwal, Ila, Ellis, Simon, Sutherland, Rebecca, Geue, Claudia, McMeekin, Nicola, Scarborough, Claire, Paul, John, Cooke, Graham, Bostock, Jennifer, Khatamzas, Elham, Wong, Nick, Brent, Andrew, Lomas, Jose, Matthews, Philippa, Wangrangsimakul, Tri, Gundle, Roger, Rogers, Mark, Taylor, Adrian, Thwaites, Guy E, Bejon, Philip

“…Management of bone and joint infection commonly includes 4-6 weeks of intravenous (IV) antibiotics, but there is little evidence to suggest that oral (PO)…”
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p38MAPK Inhibition Prevents Disease in Pemphigus Vulgaris Mice by Berkowitz, Paula, Peiqi Hu, Warren, Simon, Zhi Liu, Diaz, Luis A., Rubenstein, David S.

“…Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering skin disease characterized by detachment of keratinocytes (acantholysis). It has been…”
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Coronavirus disease 2019 (COVID-19) polymerase chain reaction (PCR) screening of asymptomatic healthcare workers in a low-prevalence setting: A single-center UK cohort study by Azamgarhi, Tariq, Maynard-Smith, Laura, Bysouth, Hannah, Warren, Simon

“…In this cohort study of UK healthcare workers, we evaluated the use of fortnightly polymerase chain reaction (PCR) screening to facilitate the safe resumption…”
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Topical application of a platelet activating factor receptor agonist suppresses phorbol ester-induced acute and chronic inflammation and has cancer chemopreventive activity in mouse skin by Sahu, Ravi P, Rezania, Samin, Ocana, Jesus A, DaSilva-Arnold, Sonia C, Bradish, Joshua R, Richey, Justin D, Warren, Simon J, Rashid, Badri, Travers, Jeffrey B, Konger, Raymond L

“…Platelet activating factor (PAF) has long been associated with acute edema and inflammatory responses. PAF acts by binding to a specific G-protein coupled…”
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Discordancy in BRAF mutations among primary and metastatic melanoma lesions: clinical implications for targeted therapy by Bradish, Joshua R, Richey, Justin D, Post, Kristin M, Meehan, Kari, Sen, Joyashree D, Malek, Amanda J, Katona, Terrence M, Warren, Simon, Logan, Theodore F, Fecher, Leslie A, Cheng, Liang

“…Systemic targeted molecular therapy, in the form of a selective BRAF inhibitor with or without a MEK inhibitor, is a standard treatment for patients with BRAF…”
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Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC‐0214 in healthy volunteers by Zhu, Rui, Chen, Hubert, Galanter, Joshua, She, Gaohong, Cai, Fang, Durk, Matthew R., Zou, Yixuan, Chen, Liuxi, Kenny, Jane R., Vadhavkar, Shweta, Warren, Simon, Taylor, Glyn, Hwang, Olivia, Eliahu, Avi, Wynne, Chris, Owen, Ryan

“…Several inflammatory cytokines that promote inflammation and pathogenesis in asthma signal through the Janus kinase 1 (JAK1) pathway. This phase I, randomized,…”
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