Search Results - "Warren, Janine"
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YAP/TAZ Activation as a Target for Treating Metastatic Cancer
Published in Cancers (10-04-2018)“…Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ) have both emerged as important drivers of cancer progression and…”
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Journal Article -
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SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis
Published in The Journal of biological chemistry (15-02-2019)“…When properly employed, targeted therapies are effective cancer treatments. However, the development of such therapies requires the identification of…”
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Journal Article -
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DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth
Published in Oncogene (23-02-2024)“…Transient early endosome (EE)-mitochondria interactions can mediate mitochondrial iron translocation, but the associated mechanisms are still elusive. We…”
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Journal Article -
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Integrin α3β1 Promotes Invasive and Metastatic Properties of Breast Cancer Cells through Induction of the Brn-2 Transcription Factor
Published in Cancers (27-01-2021)“…In the current study, we demonstrate that integrin α3β1 promotes invasive and metastatic traits of triple-negative breast cancer (TNBC) cells through induction…”
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Journal Article -
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Development of a computable phenotype using electronic health records for venous thromboembolism in medical inpatients: the Medical Inpatient Thrombosis and Hemostasis study
Published in Research and practice in thrombosis and haemostasis (01-05-2023)“…Accurate and efficient methods to identify venous thromboembolism (VTE) events in hospitalized people are needed to support large-scale studies. Validated…”
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Journal Article -
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Glycosylation of Human MUC1 Transcript Variant 2 Expressed in HeLa Cells
Published in The FASEB journal (01-04-2015)“…Abstract only The purpose of this project is to study the localization and glycosylation of MUC1 a potentially important antigen found on tumor cells. Naïve…”
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Journal Article -
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Abstract A41: Inhibition of aberrant YAP and TAZ activity to prevent metastasis formation and growth
Published in Molecular cancer research (01-08-2020)“…Abstract Metastasis causes most cancer-related deaths, and few effective therapies exist for patients with metastatic disease. The development of such…”
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Journal Article -
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Abstract A43: Identification of novel YAP/TAZ regulators in metastatic cancer
Published in Molecular cancer research (01-08-2020)“…Abstract Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the downstream effectors of the Hippo tumor inhibition…”
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Journal Article -
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Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation
Published in Molecular cancer research (01-05-2020)“…Early sorting endosomes are responsible for the trafficking and function of transferrin receptor (TfR) and EGFR. These receptors play important roles in iron…”
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Journal Article -
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Targeting Yap/Taz-Tead in Metastatic Disease
Published 01-01-2022“…Limited therapeutic options exist for patients with or at risk of developing metastatic disease. YAP and TAZ are transcriptional co-activators that often drive…”
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Dissertation -
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Plasma Copper and Zinc Concentration in Individuals with Autism Correlate with Selected Symptom Severity
Published in Nutrition and Metabolic Insights (01-01-2012)“…Aim To assess plasma zinc and copper concentration in individuals with autism and correlate these levels with symptom severity. Subjects and Methods Plasma…”
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Journal Article -
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Plasma Copper and Zinc Concentration in Individuals with Autism Correlate with Selected Symptom Severity
Published in Nutrition and metabolic insights (01-02-2012)Get full text
Journal Article -
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Peer interactions and quality learning in text -based computer -mediated communication systems
Published 01-01-2000“…Two separate studies at Washington State University examined on-line messages in university courses mediated by a prototype computer-mediated communication…”
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Dissertation