Search Results - "Warren, Hilary S."

Cutting Edge: Lectin-Like Transcript-1 Is a Ligand for the Inhibitory Human NKR-P1A Receptor by Rosen, David B, Bettadapura, Jayaram, Alsharifi, Mohammed, Mathew, Porunelloor A, Warren, Hilary S, Lanier, Lewis L

“…Increasingly, roles are emerging for C-type lectin receptors in immune regulation. One receptor whose function has remained largely enigmatic is human NKR-P1A…”
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Probiotic supplementation has little effect on peripheral blood regulatory T cells by West, Nicholas P., PhD, Horn, Peggy L., PhD, Pyne, David B., PhD, Warren, Hilary S., PhD, Asad, Suzanne, BSc (Hons), Cox, Amanda J., PhD, Lahtinen, Sampo J., PhD, Lehtinen, Markus J., PhD, Fricker, Peter A., MD, Cripps, Allan W., PhD, Fazekas de St Groth, Barbara, PhD

“…All groups showed an increase in Treg cells that appears to be related to the physical activity patterns of the study cohort. [...]regular physical activity…”
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The Intracellular Granzyme B Inhibitor, Proteinase Inhibitor 9, Is Up-Regulated During Accessory Cell Maturation and Effector Cell Degranulation, and Its Overexpression Enhances CTL Potency by Hirst, Claire E, Buzza, Marguerite S, Bird, Catherina H, Warren, Hilary S, Cameron, Paul U, Zhang, Manling, Ashton-Rickardt, Philip G, Bird, Phillip I

“…Granzyme B (grB) is a serine proteinase released by cytotoxic lymphocytes (CLs) to kill abnormal cells. GrB-mediated apoptotic pathways are conserved in…”
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Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester by Parish, Christopher R, Quah, Ben J C, Warren, Hilary S

“…This protocol outlines the carboxyfluorescein diacetate succinimidyl ester (CFSE) method for following the proliferation of human lymphocytes in vitro and…”
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CD8 T cells expressing killer Ig-like receptors and NKG2A are present in cord blood and express a more naïve phenotype than their counterparts in adult blood by Warren, Hilary S., Rana, Purna M., Rieger, Duncan T., Hewitt, Kimberly A., Dahlstrom, Jane E., Kent, Alison L.

“…We report that natural killer receptors (NKR) for major histocompatibility complex (MHC) class I molecules (MHC‐NKR), the inhibitory killer immunoglobulin‐like…”
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Target-induced natural killer cell loss as a measure of NK cell responses by Warren, Hilary S.

“…The interaction of natural killer cells with susceptible target cells triggers NK cell activation, eliciting not only NK cell cytotoxicity and cytokine…”
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Alleles of the KIR2DL4 receptor and their lack of association with pre‐eclampsia by Witt, Campbell S., Whiteway, Joanna M., Warren, Hilary S., Barden, Anne, Rogers, Marina, Martin, Annalise, Beilin, Lawrie, Christiansen, Frank T.

“…A survey of KIR2DL4 polymorphism revealed seven common sequences in the Australian population. The seven sequences encode three different amino acid sequences…”
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Use of the intracellular fluorescent dye CFSE to monitor lymphocyte migration and proliferation by Parish, Christopher R, Glidden, Megan H, Quah, Ben J C, Warren, Hilary S

“…The stable incorporation of the intracellular fluorescent dye 5-(and -6)-carboxyfluorescein diacetate succinimidyl ester (CFSE) into cells provides a powerful…”
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KIR2DL4 (CD158d) Genotype Influences Expression and Function in NK Cells by Goodridge, Jodie P, Witt, Campbell S, Christiansen, Frank T, Warren, Hilary S

“…The expression and function of the NK cell receptor KIR2DL4 are controversial. Two common alleles of the transmembrane domain of KIR2DL4 exist. The 10A allele…”
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Peripheral blood natural killer (NK) cell function in healthy adults assessed using the target-induced NK loss (TINKL) assay by Warren, Hilary S., Wu, Fan, Horn, Peggy L., Pyne, David B., West, Nicholas P., Cripps, Allan W.

“…In this technical note we provide data useful for the clinical application of the target-induced Natural Killer (NK) loss (TINKL) assay. The TINKL assay is a…”
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Evidence That the Cellular Ligand for the Human NK Cell Activation Receptor NKp30 Is Not a Heparan Sulfate Glycosaminoglycan by Warren, Hilary S, Jones, Allison L, Freeman, Craig, Bettadapura, Jayaram, Parish, Christopher R

“…NKp30 (NCR3, CD337) is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and…”
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A novel binding assay to assess specificity of monoclonal antibodies by Warren, Hilary S., Bettadapura, Jayaram

“…Dynabeads® TALON™ are uniform superparamagnetic polystyrene beads of 1μm diameter that bind 6-His-tagged recombinant proteins through Co ++-affinity binding,…”
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An economical adaptation of the RosetteSep™ procedure for NK cell enrichment from whole blood, and its use with liquid nitrogen stored peripheral blood mononuclear cells by Warren, Hilary S., Rana, Purna M.

“…This study reports an economical adaptation of the RosetteSep™ procedure for enrichment of NK cells designed for whole blood and its use with liquid nitrogen…”
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NK cells and apoptosis by Warren, Hilary S, Smyth, Mark J

“…Natural killer (NK) cells are a cell of the innate immune system that play an important role in the early response to viral infections and tumours. Natural…”
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The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: Natural killer cell section report by Warren, Hilary S.

“…Monoclonal antibodies submitted to the natural killer (NK) cell section of the Eighth International Workshop on Human Leucocyte Differentiation Antigens…”
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Quantitative Analysis of the Effect of CD16 Ligation on Human NK Cell Proliferation by Warren, Hilary S, Kinnear, Beverley F

“…CD16 (Fc gammaRIIIA), the low affinity receptor for IgG, is expressed on the majority of human peripheral blood NK cells. Ligation of CD16 with mAb or immune…”
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Functional inhibitory human leucocyte antigen class I receptors on natural killer (NK) cells in patients with chronic NK lymphocytosis by Warren, Hilary S., Christiansen, Frank T., Witt, Campbell S.

“…Chronic natural killer (NK) lymphocytosis is a rare disorder characterized by an indolent clinical course. Despite high NK cell numbers, many patients present…”
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Using carboxyfluorescein diacetate succinimidyl ester to monitor human NK cell division: Analysis of the effect of activating and inhibitory class I MHC receptors by Warren, Hilary S

“…Human NK cells labelled intracellularly with the fluorescent dye 5‐ and 6‐carboxyfluorescein diacetate succinimidyl ester (CFSE) were used to assess the effect…”
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Proliferation of alloreactive human natural killer cells independent of specific allogeneic stimulation by Warren, H S, Kinnear, B F, Witt, C S, Christiansen, F T

“…This study establishes that natural killer (NK) cells cytolytic for B-lymphoblastoid cell lines (B-LCL) expressing NK-defined alloantigens can be stimulated to…”
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Biphasic response of NK cells expressing both activating and inhibitory killer Ig-like receptors by Warren, Hilary S., Campbell, Anita J., Waldron, John C., Lanier, Lewis L.

“…NK cells can co-express inhibitory and activating killer Ig-like receptors (KIR) recognizing the same HLA class I ligand. We present evidence from experiments…”
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