Search Results - "Warren, Cirle"

Clostridioides difficile Infection in Children: Recent Updates on Epidemiology, Diagnosis, Therapy by Shirley, Debbie-Ann, Tornel, William, Warren, Cirle A, Moonah, Shannon

“…Clostridioides (formerly Clostridium) difficile is the most important infectious cause of antibiotic-associated diarrhea worldwide and a leading cause of…”
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Prevention and treatment of recurrent Clostridioides difficile infection by Shin, Jae Hyun, Warren, Cirle A

“…PURPOSE OF REVIEWClostridioides difficile infection (CDI) is a significant burden on the health system, especially due to high recurrence rates. Since the…”
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Older Is Not Wiser, Immunologically Speaking: Effect of Aging on Host Response to Clostridium difficile Infections by Shin, Jae Hyun, High, Kevin P, Warren, Cirle A

“…Clostridium difficile infection (CDI) is the most common cause of antibiotic-associated diarrhea and a significant burden on the health care system. Aging has…”
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Quantifying bacterial spore germination by single-cell impedance cytometry for assessment of host microbiota susceptibility to Clostridioides difficile infection by Moore, John H., Salahi, Armita, Honrado, Carlos, Warburton, Christopher, Warren, Cirle A., Swami, Nathan S.

“…The germination of ingested spores is often a necessary first step required for enabling bacterial outgrowth and host colonization, as in the case of…”
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Drug Repurposing of the Alcohol Abuse Medication Disulfiram as an Anti-Parasitic Agent by Shirley, Debbie-Ann, Sharma, Ishrya, Warren, Cirle A, Moonah, Shannon

“…Parasitic infections contribute significantly to worldwide morbidity and mortality. Antibiotic treatment is essential for managing patients infected with these…”
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Impact of Tigecycline on C. difficile Outcomes: Case Series and Propensity-Matched Retrospective Study by Phillips, Emma C, Warren, Cirle A, Ma, Jennie Z, Madden, Gregory R

“…This case series and propensity-matched cohort study on the use of tigecycline in Clostridioides difficile infection (CDI) evaluated the effect of tigecycline…”
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S195 Efficacy and Safety of Fecal Microbiota, Live-jslm in Older Participants With Recurrent Clostridioides difficile Infection and Underlying Comorbidities: An Ad Hoc Analysis of an Open-Label, Phase 3 Study by Warren, Cirle A., Tillotson, Glenn, Guthmueller, Beth, Thul, Joan, Feuerstadt, Paul, Gonzales-Luna, Anne J., Carlson, Travis J.

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Bacteroides and related species: The keystone taxa of the human gut microbiota by Shin, Jae Hyun, Tillotson, Glenn, MacKenzie, Tiffany N., Warren, Cirle A., Wexler, Hannah M., Goldstein, Ellie J.C.

“…Microbial communities play a significant role in maintaining ecosystems in a healthy homeostasis. Presently, in the human gastrointestinal tract, there are…”
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Validation of Clinical Risk Models for Clostridioides difficile-Attributable Outcomes by Madden, Gregory R., Petri, William A., Costa, Deiziane V. S., Warren, Cirle A., Ma, Jennie Z., Sifri, Costi D.

“…Clostridioides difficile is the leading health care-associated pathogen, leading to substantial morbidity and mortality; however, there is no widely accepted…”
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Clostridioides difficile colonization among very young children in resource-limited settings by Brennhofer, Stephanie A., Rogawski McQuade, Elizabeth T., Liu, Jie, Guerrant, Richard L., Platts-Mills, James A., Warren, Cirle A.

“…To describe the epidemiology and risk factors for Clostridioides difficile (C. difficile) colonization among young children in eight low-resource settings. We…”
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Single-cell electro-phenotyping for rapid assessment of Clostridium difficile heterogeneity under vancomycin treatment at sub-MIC (minimum inhibitory concentration) levels by Rohani, Ali, Moore, John H., Su, Yi-Hsuan, Stagnaro, Victoria, Warren, Cirle, Swami, Nathan S.

“…[Display omitted] •Microbial-culture independent antibiotic susceptibility assessment using electrophysiology.•Susceptibility to MIC vancomycin levels…”
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The Importance of a Broad Consortium of Bacteria for a Healthy Gastrointestinal tract: A Narrative Review of the Live Biotherapeutic Product REBYOTA by Tillotson, Glenn, Vedantam, Gayatri, Shin, Jae Hyun, Warren, Cirle A

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In vitro activity of amixicile against T. vaginalis from clinical isolates by Jain, Eisha, Zaenker, Edna I., Hoffman, Paul S., Warren, Cirle A.

“…Trichomoniasis is a sexually transmitted infection in humans caused by the protozoan Trichomonas vaginalis, the leading causative agent of vaginitis in women…”
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Innate Immune Response and Outcome of Clostridium difficile Infection Are Dependent on Fecal Bacterial Composition in the Aged Host by Shin, Jae Hyun, Gao, Yingnan, Moore, John H, Bolick, David T, Kolling, Glynis L, Wu, Martin, Warren, Cirle A

“…Mouse model of Clostridium difficile infection shows detrimental effect of aging on outcome associated with decreased initial innate immune response, which can…”
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Influence of Binary Toxin Gene Detection and Decreased Susceptibility to Antibiotics among Clostridioides difficile Strains on Disease Severity: a Single-Center Study by Costa, Deiziane V S, Pham, Natalie V S, Hays, Rachel A, Bolick, David T, Goldbeck, Sophia M, Poulter, Melinda D, Hoang, Sook C, Shin, Jae H, Wu, Martin, Warren, Cirle A

“…Clostridioides difficile infection (CDI) is the fifth leading cause of death from nonmalignant gastrointestinal disease in the United States. The contribution…”
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Clostridioides difficile infection promotes gastrointestinal dysfunction in human and mice post-acute phase of the disease by Costa, Deiziane V.S., Pham, Natalie, Loureiro, Andrea V., Yang, Suemin E., Behm, Brian W., Warren, Cirle A.

“…In the US, Clostridioides difficile (C. difficile) infection (CDI) is the 8th leading cause of hospital readmission and 7th for mortality among all…”
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Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review by Fernandez-Cotarelo, Maria-Jose, Jackson-Akers, Jasmine Y, Nagy-Agren, Stephanie E, Warren, Cirle A

“…Clostridioides difficile infection (CDI) is the leading cause of antibiotic-related diarrhea and healthcare-associated infections, affecting in particular…”
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5-Fluorouracil Induces Enteric Neuron Death and Glial Activation During Intestinal Mucositis via a S100B-RAGE-NFκB-Dependent Pathway by Costa, Deiziane V. S., Bon-Frauches, Ana C., Silva, Angeline M. H. P., Lima-Júnior, Roberto C. P., Martins, Conceição S., Leitão, Renata F. C., Freitas, Gutierrez B., Castelucci, Patricia, Bolick, David T., Guerrant, Richard L., Warren, Cirle A., Moura-Neto, Vivaldo, Brito, Gerly A. C.

“…5-Fluorouracil (5-FU) is an anticancer agent whose main side effects include intestinal mucositis associated with intestinal motility alterations maybe due to…”
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Defined Nutrient Diets Alter Susceptibility to Clostridium difficile Associated Disease in a Murine Model by Moore, John H, Pinheiro, Caio C D, Zaenker, Edna I, Bolick, David T, Kolling, Glynis L, van Opstal, Edward, Noronha, Francisco J D, De Medeiros, Pedro H Q S, Rodriguez, Raphael S, Lima, Aldo A, Guerrant, Richard L, Warren, Cirle A

“…Clostridium difficile is a major identifiable and treatable cause of antibiotic-associated diarrhea. Poor nutritional status contributes to mortality through…”
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Dielectrophoretic Monitoring and Interstrain Separation of Intact Clostridium difficile Based on Their S(Surface)-Layers by Su, Yi-Hsuan, Warren, Cirle A, Guerrant, Richard L, Swami, Nathan S

“…Clostridium difficile (C. difficile) infection (CDI) rates have exhibited a steady rise worldwide over the last two decades and the infection poses a global…”
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