Search Results - "Warren, Anna J"

Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample by Keown, Jeremy R., Crawshaw, Adam D., Trincao, Jose, Carrique, Loïc, Gildea, Richard J., Horrell, Sam, Warren, Anna J., Axford, Danny, Owen, Robin, Evans, Gwyndaf, Bézier, Annie, Metcalf, Peter, Grimes, Jonathan M.

“…Infectious protein crystals are an essential part of the viral lifecycle for double-stranded DNA Baculoviridae and double-stranded RNA cypoviruses. These viral…”
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Direct measurement of X‐ray‐induced heating of microcrystals by Warren, Anna J., Axford, Danny, Owen, Robin L.

“…Temperature control is a key aspect of macromolecular crystallography, with the technique of cryocooling routinely being used to mitigate X‐ray‐induced damage…”
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A 2.8 Å Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase by Morgan, Harry, Lipka-Lloyd, Magdalena, Warren, Anna J, Hughes, Naomi, Holmes, John, Burton, Nicolas P, Mahenthiralingam, Eshwar, Bax, Ben D

“…Since 2000, some thirteen quinolones and fluoroquinolones have been developed and have come to market. The quinolones, one of the most successful classes of…”
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VMXm - A sub-micron focus macromolecular crystallography beamline at Diamond Light Source by Warren, Anna J, Trincao, Jose, Crawshaw, Adam D, Beale, Emma V, Duller, Graham, Stallwood, Andrew, Lunnon, Mark, Littlewood, Richard, Prescott, Adam, Foster, Andrew, Smith, Neil, Rehm, Guenther, Gayadeen, Sandira, Bloomer, Christopher, Alianelli, Lucia, Laundy, David, Sutter, John, Cahill, Leo, Evans, Gwyndaf

“…VMXm joins the suite of operational macromolecular crystallography beamlines at Diamond Light Source. It has been designed to optimize rotation data…”
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Solid-State Interconversions: Unique 100 % Reversible Transformations between the Ground and Metastable States in Single-Crystals of a Series of Nickel(II) Nitro Complexes by Warren, Mark R., Easun, Timothy L., Brayshaw, Simon K., Deeth, Robert J., George, Michael W., Johnson, Andrew L., Schiffers, Stefanie, Teat, Simon J., Warren, Anna J., Warren, John E., Wilson, Chick C., Woodall, Christopher H., Raithby, Paul R.

“…The solid‐state, low‐temperature linkage isomerism in a series of five square planar group 10 phosphino nitro complexes have been investigated by a combination…”
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Small-rotative fixed-target serial synchrotron crystallography (SR-FT-SSX) for molecular crystals by Lewis, Sam G., Coulson, Ben A., Warren, Anna J., Warren, Mark R., Hatcher, Lauren E.

“…The increasing availability of ultrabright Light Sources is facilitating the study of smaller crystals at faster timescales but with an increased risk of…”
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Scanning electron microscopy as a method for sample visualization in protein X-ray crystallography by Beale, Emma V, Warren, Anna J, Trincão, José, Beilsten-Edmands, James, Crawshaw, Adam D, Sutton, Geoff, Stuart, David, Evans, Gwyndaf

“…Developing methods to determine high-resolution structures from micrometre- or even submicrometre-sized protein crystals has become increasingly important in…”
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Alkyne Derivatives of SARS-CoV‑2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine by Brewitz, Lennart, Dumjahn, Leo, Zhao, Yilin, Owen, C. David, Laidlaw, Stephen M., Malla, Tika R., Nguyen, Dung, Lukacik, Petra, Salah, Eidarus, Crawshaw, Adam D., Warren, Anna J., Trincao, Jose, Strain-Damerell, Claire, Carroll, Miles W., Walsh, Martin A., Schofield, Christopher J.

“…Nirmatrelvir (PF-07321332) is a nitrile-bearing small-molecule inhibitor that, in combination with ritonavir, is used to treat infections by severe acute…”
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Crystals in the community and the classroom by Murray, Claire, Maynard-Casely, Helen E, Harrington, Ross, McCready, Stephanie, Sneddon, Duncan J, Thomas, Lynne, Warren, Anna J

“…The growing pressure on school curricula has meant crystals and the science of crystallography have been cut from or made optional for many educational…”
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How Do Gepotidacin and Zoliflodacin Stabilize DNA Cleavage Complexes with Bacterial Type IIA Topoisomerases? 1. Experimental Definition of Metal Binding Sites by Morgan, Harry, Nicholls, Robert A, Warren, Anna J, Ward, Simon E, Evans, Gwyndaf, Long, Fei, Murshudov, Garib N, Duman, Ramona, Bax, Benjamin D

“…One of the challenges for experimental structural biology in the 21st century is to see chemical reactions happen. Staphylococcus aureus (S. aureus) DNA gyrase…”
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In vacuo X-ray data collection from graphene-wrapped protein crystals by Warren, Anna J., Crawshaw, Adam D., Trincao, Jose, Aller, Pierre, Alcock, Simon, Nistea, Ioana, Salgado, Paula S., Evans, Gwyndaf

“…The measurement of diffraction data from macromolecular crystal samples held in vacuo holds the promise of a very low X‐ray background and zero absorption of…”
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Visualization of membrane protein crystals in lipid cubic phase using X-ray imaging by Warren, Anna J., Armour, Wes, Axford, Danny, Basham, Mark, Connolley, Thomas, Hall, David R., Horrell, Sam, McAuley, Katherine E., Mykhaylyk, Vitaliy, Wagner, Armin, Evans, Gwyndaf

“…The focus in macromolecular crystallography is moving towards even more challenging target proteins that often crystallize on much smaller scales and are…”
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Exploiting Microbeams for Membrane Protein Structure Determination by Warren, Anna J, Axford, Danny, Paterson, Neil G, Owen, Robin L

“…A reproducible, and sample independent means of predictably obtaining large, well-ordered crystals has proven elusive in macromolecular crystallography. In the…”
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A 2.8 Å resolution crystal structure of Staphylococcus aureus DNA gyrase in a DNA-cleavage complex with zoliflodacin suggests a mechanism for activity against quinolone-resistant bacteria by Morgan, Harry, Lipka-Lloyd, Magdalena, Warren, Anna J., Bax, Benjamin D.

“…Abstract only…”
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In vacuo X-ray data collection from graphene-wrapped protein crystals by Warren, Anna J., Crawshaw, Adam D., Trincao, Jose, Aller, Pierre, Alcock, Simon, Nistea, Ioana, Evans, Gwyndaf

“…Abstract only…”
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Visualisation of membrane protein crystals in lipid cubic phase using X-ray imaging by Warren, Anna J., Armour, Wes, Axford, Danny, Basham, Mark, Connolley, Thomas, Hall, David R., Horrell, Sam, McAuley, Katherine E., Mykhaylyk, Vitaliy, Wagner, Armin, Evans, Gwyndaf

“…Abstract only…”
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Biology Recipe: Garnish Well, and Serve by Anna, Warren J.

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