Search Results - "Warnock, Dale E"
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Characterization of the human heart mitochondrial proteome
Published in Nature biotechnology (01-03-2003)“…To gain a better understanding of the critical role of mitochondria in cell function, we have compiled an extensive catalogue of the mitochondrial proteome…”
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An Alternative Strategy To Determine the Mitochondrial Proteome Using Sucrose Gradient Fractionation and 1D PAGE on Highly Purified Human Heart Mitochondria
Published in Journal of proteome research (01-09-2002)“…An alternative strategy for mitochondrial proteomics is described that is complementary to previous investigations using 2D PAGE techniques. The strategy…”
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Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I
Published in Molecular biology of the cell (01-12-1997)“…To begin to understand mechanistic differences in endocytosis in neurons and nonneuronal cells, we have compared the biochemical properties of the ubiquitously…”
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Induction of Mutant Dynamin Specifically Blocks Endocytic Coated Vesicle Formation
Published in The Journal of cell biology (01-11-1994)“…Dynamin is the mammalian homologue to the Drosophila shibire gene product. Mutations in this 100-kD GTPase cause a pleiotropic defect in endocytosis. To…”
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Expanded Coverage of the Human Heart Mitochondrial Proteome Using Multidimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published in Journal of proteome research (01-05-2004)“…Recent evidence suggests that mitochondria are closely linked with the aging process and degenerative disorders such as Alzheimer's disease and Parkinson's…”
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Dynamin Self-assembly Stimulates Its GTPase Activity
Published in The Journal of biological chemistry (13-09-1996)“…GTP hydrolysis by dynamin is required to drive coated vesicle budding at the plasma membrane. A diverse set of molecules including microtubules, grb2, and…”
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Dynamin GTPase, a force-generating molecular switch
Published in BioEssays (01-11-1996)“…Dynamin is a GTPase that regulates late events in clathrin-coated vesicle formation. Our current working model suggests that dynamin is targeted to coated pits…”
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Identification of protein associations in organelles, using mass spectrometry-based proteomics
Published in Mass spectrometry reviews (01-07-2004)“…I. Introduction 260 II. Progress on Mapping Organellar Proteomes and Their Component Protein Complexes 260 A. Mitochondria 260 1. Global Analysis 260 …”
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Transport of Newly Synthesized Glucosylceramide to the Plasma Membrane by a Non-Golgi Pathway
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-1994)“…High-gradient magnetic affinity chromatography (HIMAC) has been used to obtain highly enriched plasma membranes, free of intracellular membrane contaminants,…”
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Domain structure and intramolecular regulation of dynamin GTPase
Published in The EMBO journal (17-11-1997)“…Dynamin is a 100 kDa GTPase required for receptor‐mediated endocytosis, functioning as the key regulator of the late stages of clathrin‐coated vesicle budding…”
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Dynamin GTPase is stimulated by crosslinking through the C‐terminal proline‐rich domain
Published in The EMBO journal (03-04-1995)“…Dynamin is a 100 kDa GTPase required for endocytic‐coated vesicle formation. Recombinant human neuronal dynamin (dynamin‐1) was used for monoclonal antibody…”
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Expression, purification, and functional assays for self-association of dynamin-1
Published in Methods in enzymology (2001)Get more information
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Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography
Published in The Journal of biological chemistry (15-05-1993)“…We have utilized wheat germ agglutinin conjugated to iron/dextran particles in conjunction with high gradient magnetic affinity chromatography (HIMAC) to…”
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