Search Results - "Warner, John H."

Huntington disease: natural history, biomarkers and prospects for therapeutics by Ross, Christopher A., Aylward, Elizabeth H., Wild, Edward J., Langbehn, Douglas R., Long, Jeffrey D., Warner, John H., Scahill, Rachael I., Leavitt, Blair R., Stout, Julie C., Paulsen, Jane S., Reilmann, Ralf, Unschuld, Paul G., Wexler, Alice, Margolis, Russell L., Tabrizi, Sarah J.

“…Key Points No disease-modifying treatments are currently available for Huntington disease (HD), but clinical trials of potential compounds are imminent;…”
Get full text

Baseline multimodal information predicts future motor impairment in premanifest Huntington's disease by Castro, Eduardo, Polosecki, Pablo, Rish, Irina, Pustina, Dorian, Warner, John H., Wood, Andrew, Sampaio, Cristina, Cecchi, Guillermo A.

“…In Huntington's disease (HD), accurate estimates of expected future motor impairments are key for clinical trials. Individual prognosis is only partially…”
Get full text

Indexing disease progression at study entry with individuals at-risk for Huntington disease by Zhang, Ying, Long, Jeffrey D., Mills, James A., Warner, John H., Lu, Wenjing, Paulsen, Jane S.

“…The identification of clinical and biological markers of disease in persons at risk for Huntington disease (HD) has increased in efforts to better quantify and…”
Get full text

Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers by Warner, John H, Liang, Qiwei, Sarkar, Mohamadi, Mendes, Paul E, Roethig, Hans J

“…This article describes the data mining analysis of a clinical exposure study of 3585 adult smokers and 1077 nonsmokers. The analysis focused on developing…”
Get full text

Huntington's Disease Progression: A Population Modeling Approach to Characterization Using Clinical Rating Scales by Sun, Wan, Zhou, Di, Warner, John H., Langbehn, Douglas R., Hochhaus, Guenther, Wang, Yaning

“…Development of effective therapeutics that slow Huntington's disease progression is a research priority that requires an understanding of natural disease…”
Get full text

Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate by Polosecki, Pablo, Castro, Eduardo, Rish, Irina, Pustina, Dorian, Warner, John H., Wood, Andrew, Sampaio, Cristina, Cecchi, Guillermo A.

“…Patient stratification is critical for the sensitivity of clinical trials at early stages of neurodegenerative disorders. In Huntington’s disease (HD), genetic…”
Get full text

Estimating the causal effects of modifiable, non-genetic factors on Huntington disease progression using propensity score weighting by Griffin, Beth Ann, Booth, Marika Suttorp, Busse, Monica, Wild, Edward J., Setodji, Claude, Warner, John H., Sampaio, Cristina, Mohan, Amrita

“…Despite being genetically inherited, it is unclear how non-genetic factors (e.g., substance use, employment) might contribute to the progression and severity…”
Get full text

PET Molecular Imaging of Phosphodiesterase 10A: An Early Biomarker of Huntington's Disease Progression by Fazio, Patrik, Fitzer‐Attas, Cheryl J., Mrzljak, Ladislav, Bronzova, Juliana, Nag, Sangram, Warner, John H., Landwehrmeyer, Bernhard, Al‐Tawil, Nabil, Halldin, Christer, Forsberg, Anton, Ware, Jennifer, Dilda, Valentina, Wood, Andrew, Sampaio, Cristina, Varrone, Andrea

“…Background Changes in phosphodiesterase 10A enzyme levels may be a suitable biomarker of disease progression in Huntington's disease. Objectives To evaluate…”
Get full text

Standardizing the CAP Score in Huntington's Disease by Predicting Age-at-Onset by Warner, John H, Long, Jeffrey D, Mills, James A, Langbehn, Douglas R, Ware, Jennifer, Mohan, Amrita, Sampaio, Cristina

“…Huntington's disease (HD) is an autosomal dominant, neurological disease caused by an expanded CAG repeat near the N-terminus of the huntingtin (HTT) gene. A…”
Get more information

The temporal event-based model: Learning event timelines in progressive diseases by Wijeratne, Peter A, Eshaghi, Arman, Scotton, William J, Kohli, Maitrei, Aksman, Leon, Oxtoby, Neil P, Pustina, Dorian, Warner, John H, Paulsen, Jane S, Scahill, Rachael I, Sampaio, Cristina, Tabrizi, Sarah J, Alexander, Daniel C

“…Timelines of events, such as symptom appearance or a change in biomarker value, provide powerful signatures that characterise progressive diseases…”
Get full text

The direct medical costs of Huntington's disease by stage. A retrospective commercial and Medicaid claims data analysis by Divino, Victoria, Dekoven, Mitch, Warner, John H, Giuliano, Joseph, Anderson, Karen E, Langbehn, Douglas, Lee, Won Chan

“…This study quantified the direct healthcare costs and major cost drivers among patients with Huntington's disease (HD), by disease stage in commercial and…”
Get more information

Interventional differences among Huntington's disease patients by disease progression in commercial and medicaid populations by Anderson, Karen E, Divino, Victoria, DeKoven, Mitch, Langbehn, Douglas, Warner, John H, Giuliano, Joseph, Lee, Won Chan

“…Huntington's disease (HD) is a progressive neurodegenerative disease that spans distinct disease stages over 15-20 years. Various interventions are available…”
Get more information

Assessment of Day-to-Day Functioning in Prodromal and Early Huntington Disease by Vaccarino, Anthony L, Sills, Terrence, Anderson, Karen E, Endicott, Jean, Giuliano, Joseph, Guttman, Mark, Ho, Aileen K, Kupchak, Peter, Paulsen, Jane S, Warner, John H, Williams, Janet, Evans, Ken

“…The Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a…”
Get full text

Assessment of motor symptoms and functional impact in prodromal and early huntington disease by Vaccarino, Anthony L, Sills, Terrence, Anderson, Karen E, Biglan, Kevin, Borowsky, Beth, Giuliano, Joseph, Guttman, Mark, Ho, Aileen K, Kennard, Christopher, Kupchak, Peter, Landwehrmeyer, G Bernhard, Michell, Andrew, Paulsen, Jane S, Reilmann, Ralf, van Kammen, Daniel P, Warner, John H, Evans, Ken

“…The Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a…”
Get full text

Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers by Warner, John H, Liang, Qiwei, Sarkar, Mohamadi, Mendes, Paul E, Roethig, Hans J

Get full text

Predictors of fecundability and conception waits among the Dogon of Mali by Strassmann, Beverly I., Warner, John H.

“…Surprisingly little is known about the mechanisms that underlie variation in female fertility in humans. Data on this topic are nonetheless vital to a number…”
Get full text

Wilderness, Incorporation, and Earthquakes: Christo, Jeanne-Claude, Niki de St. Phalle and the Embodied California Landscape by Warner, John-Michael H

“…Christo and Jeanne-Claude’s Running Fence, begun 1972 and installed in 1976, and Niki de St. Phalle’s Queen Califia’s Magical Circle, dedicated 2003, in…”
Get full text

An Aeroplane for Survey Work: A Pusher Type with Twin‐Fin Tail and Tricycle Undercarriage by Warner, John H.

“…THE needs of modern aerial survey work become ever more exacting and it was felt that a high performance aeroplane, specialty designed to suit the particular…”
Get full text

Chapter 2 - Medicine, Media, and the Dramaturgy of Biomedical Research: Historical Perspectives by Warner, John H.

“…This chapter offers a historical perspective on relations among medical scientists, the mass media, and public perception and expectation. It also provides a…”
Get full text

Information effect on the perception of pain during electromyography by Richardson, J K, Evans, J E, Warner, J H

“…Pain during the performance of electromyography (EMG) is an important clinical problem because pain distresses the patient and can interfere with diagnostic…”
Get more information