Search Results - "Warner, DS"

Apolipoprotein E Protects against NMDA Excitotoxicity by Aono, Mitsuo, Lee, Yoonki, Grant, Elfrida R., Zivin, Robert A., Pearlstein, Robert D., Warner, David S., Bennett, Ellen R., Laskowitz, Daniel T.

“…Preclinical and clinical evidence implicates a role for endogenous apolipoprotein E in modifying the response of the brain to focal and global ischemia. To…”
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A comparison of 0.5% bupivacaine, 0.5% ropivacaine, and 0.75% ropivacaine for interscalene brachial plexus block by KLEIN, S. M, GREENGRASS, R. A, STEELE, S. M, D'ERCOLE, F. J, SPEER, K. P, GLEASON, D. H, DELONG, E. R, WARNER, D. S

“…The onset time and duration of action of ropivacaine during an interscalene block are not known. The potentially improved safety profile of ropivacaine may…”
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A comparison of the remifentanil and fentanyl adverse effect profile in a multicenter phase IV study by Joshi, Girish P, Warner, David S, Twersky, Rebecca S, Fleisher, Lee A

“…To compare the frequency of adverse effects of remifentanil and fentanyl in a large and diverse patient population. Prospective, randomized, open-label study…”
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Intracranial Pressure and Hemodynamic Effects of Remifentanil Versus Alfentanil in Patients Undergoing Supratentorial Craniotomy by Warner, David S., Hindman, Bradley J., Todd, Michael M., Sawin, Paul D., Kirchner, Jerry, Roland, Carl L., Jamerson, Brenda D.

“…Remifentanil hydrochloride is an ultra-short-acting esterase metabolized mu-opioid receptor agonist. The purpose of this study was to provide preliminary…”
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Relative Neuroprotective Effects of Dizocilpine and Isoflurane During Focal Cerebral Ischemia in the Rat by SARRAF-YAZDI, S, HUAXIN SHENG, MIURA, Y, MCFARLANE, C, DEXTER, F, PEARLSTEIN, R, WARNER, D. S

“…Both dizocilpine (MK-801) and isoflurane antagonize glutamatergic neurotransmission. In this study, we examined the relative neuroprotective effects of these…”
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Resuscitation and emergency care in drowning: A scoping review by Bierens, J., Abelairas-Gomez, C., Barcala Furelos, R., Beerman, S., Claesson, A., Dunne, C., Elsenga, H.E., Morgan, P., Mecrow, T., Pereira, J.C., Scapigliati, A., Seesink, J., Schmidt, A., Sempsrott, J., Szpilman, D., Warner, D.S., Webber, J., Johnson, S., Olasveengen, T., Morley, P.T., Perkins, G.D.

“…The ILCOR Basic Life Support Task Force and the international drowning research community considered it timely to undertake a scoping review of the literature…”
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Oxidants, antioxidants and the ischemic brain by Warner, David S, Sheng, Huaxin, Batinić-Haberle, Ines

“…Despite numerous defenses, the brain is vulnerable to oxidative stress resulting from ischemia/reperfusion. Excitotoxic stimulation of superoxide and nitric…”
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APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response by Lynch, John R., Tang, Wen, Wang, Haichen, Vitek, Michael P., Bennett, Ellen R., Sullivan, Patrick M., Warner, David S., Laskowitz, Daniel T.

“…Human apolipoprotein E is the major apolipoprotein expressed in the brain and exists as three isoforms, designated E2, E3, and E4. Although evidence suggests…”
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Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage : Results of a pilot randomized clinical trial by LYNCH, John R, HAICHEN WANG, LASKOWITZ, Daniel T, MCGIRT, Matthew J, FLOYD, James, FRIEDMAN, Allan H, COON, Alexander L, BLESSING, Robert, ALEXANDER, Michael J, GRAFFAGNINO, Carmelo, WARNER, David S

“…Cerebral vasospasm remains a major source of morbidity after aneurysmal subarachnoid hemorrhage (SAH). We demonstrate that simvastatin reduces serum markers of…”
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Brain oxygenation and energy metabolism: part I-biological function and pathophysiology by Zauner, Alois, Daugherty, Wilson P, Bullock, M Ross, Warner, David S

“…CONTINUOUS OXYGEN DELIVERY and CO(2) clearance are paramount in the maintenance of normal brain function and tissue integrity. Under normal conditions, aerobic…”
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Peripheral Nerve Block Techniques for Ambulatory Surgery by Klein, Stephen M., Evans, Holly, Nielsen, Karen C., Tucker, Marcy S., Warner, David S., Steele, Susan M.

“…Peripheral nerve blocks (PNBs) have an increasingly important role in ambulatory anesthesia and have many characteristics of the ideal outpatient…”
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Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage by MCGIRT, Matthew J, LYNCH, John R, PARRA, Augusto, HUAXIN SHENG, PEARLSTEIN, Robert D, LASKOWITZ, Daniel T, PELLIGRINO, Dale A, WARNER, David S

“…Endothelial nitric oxide synthase (eNOS) activity is decreased after subarachnoid hemorrhage (SAH). Simvastatin increases eNOS activity. We hypothesized that…”
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A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury by Lynch, John R., Wang, Haichen, Mace, Brian, Leinenweber, Stephen, Warner, David S., Bennett, Ellen R., Vitek, Michael P., McKenna, Suzanne, Laskowitz, Daniel T.

“…Although apolipoprotein E4 (APOE4) was initially identified as a susceptibility gene for the development of Alzheimer's disease, the presence of the APOE4…”
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Isoflurane-Induced Neuronal Degeneration: An Evaluation in Organotypic Hippocampal Slice Cultures by Wise-Faberowski, Lisa, Zhang, Haito, Ing, Richard, Pearlstein, Robert D., Warner, David S.

“…Prolonged exposure of postnatal day (PND) 7 rat pups to anesthetics, which act via N-methyl-d-aspartate antagonism and/or γ-amino butyric acid enhancement,…”
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A Retrospective Analysis of a Remifentanil/Propofol General Anesthetic for Craniotomy Before Awake Functional Brain Mapping by Keifer, John C., Dentchev, Dimitar, Little, Kenneth, Warner, David S., Friedman, Allan H., Borel, Cecil O.

“…We performed this study to summarize drug dosing, physiologic responses, and anesthetic complications from an IV general anesthetic technique for patients…”
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The neuroprotective effect of Xenon administration during transient middle cerebral artery occlusion in mice by HOMI, H. Mayumi, YOKOO, Noriko, DAQING MA, WARNER, David S, FRANKS, Nicholas P, MAZE, Mervyn, GROCOTT, Hilary P

“…Xenon has been shown to be neuroprotective in several models of in vitro and in vivo neuronal injury. However, its putative neuroprotective properties have not…”
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Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage by Borel, Cecil O, McKee, Andy, Parra, Augusto, Haglund, Michael M, Solan, Amy, Prabhakar, Vikas, Sheng, Huaxin, Warner, David S, Niklason, Laura

“…During vasospasm after subarachnoid hemorrhage (SAH), cerebral blood vessels show structural changes consistent with the actions of vascular mitogens. We…”
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Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump by KLEIN, Stephen M, GRANT, Stuart A, GREENGRASS, Roy A, NIELSEN, Karen C, SPEER, Kevin P, WHITE, William, WARNER, David S, STEELE, Susan M

“…Continuous interscalene brachial plexus blockade traditionally requires a hospital stay for local anesthetic infusion, and achieving consistent catheter…”
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Effects of isoflurane versus fentanyl-nitrous oxide anesthesia on long-term outcome from severe forebrain ischemia in the rat by ELSERSY, Hazem, HUAXIN SHENG, LYNCH, John R, MOLDOVAN, Maria, PEARLSTEIN, Robert D, WARNER, David S

“…This study examined long-term outcome from severe forebrain ischemia in the rat, as a function of anesthetic given during the ischemic injury. Rats were…”
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Perioperative Neuroprotection: Are We Asking the Right Questions? by Warner, David S

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