Search Results - "Warner, Andrew"
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Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized Trial
Published in Journal of clinical oncology (01-09-2020)“…The oligometastatic paradigm hypothesizes that patients with a limited number of metastases may achieve long-term disease control, or even cure, if all sites…”
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TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
Published in Nature medicine (01-03-2021)“…Genetically engineered T cell therapy can induce remarkable tumor responses in hematologic malignancies. However, it is not known if this type of therapy can…”
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Formation of C(sp2)Boronate Esters by Borylative Cyclization of Alkynes Using BCl3
Published in Angewandte Chemie International Edition (14-09-2015)“…BCl3 is an inexpensive electrophile which induces the borylative cyclization of a wide range of substituted alkynes to regioselectively form polycycles…”
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BCl3‐Induced Annulative Oxo‐ and Thioboration for the Formation of C3‐Borylated Benzofurans and Benzothiophenes
Published in Angewandte Chemie International Edition (02-01-2017)“…BCl3‐induced borylative cyclization of aryl‐alkynes possessing ortho‐EMe (E=S, O) groups represents a simple, metal‐free method for the formation of…”
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Randomized Trial of Radiotherapy Versus Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma: Long-Term Results of the ORATOR Trial
Published in Journal of clinical oncology (10-03-2022)“…The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has risen rapidly, because of an epidemic of human papillomavirus infection. The optimal…”
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Pooled analysis of stereotactic ablative radiotherapy for primary renal cell carcinoma: A report from the International Radiosurgery Oncology Consortium for Kidney (IROCK)
Published in Cancer (01-03-2018)“…BACKGROUND Stereotactic ablative radiotherapy (SABR) is an emerging therapy for primary renal cell carcinoma. The authors assessed safety, efficacy, and…”
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An Individual Patient Data Metaanalysis of Outcomes and Prognostic Factors After Treatment of Oligometastatic Non–Small-Cell Lung Cancer
Published in Clinical lung cancer (01-09-2014)“…Micro-Abstract The management of patients with oligometastatic non–small-cell lung cancer (NSCLC) is controversial. The findings of this metaanalysis of 757…”
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Predicting Esophagitis After Chemoradiation Therapy for Non-Small Cell Lung Cancer: An Individual Patient Data Meta-Analysis
Published in International journal of radiation oncology, biology, physics (15-11-2013)“…Purpose Concurrent chemoradiation therapy (CCRT) improves survival compared with sequential treatment for locally advanced non-small cell lung cancer, but it…”
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Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial
Published in BMC cancer (19-08-2019)“…Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment option for patients with oligometastatic disease. SABR delivers precise, high-dose,…”
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CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells
Published in International journal of molecular sciences (30-01-2023)“…Elevated expression of CD47 in some cancers is associated with poor survival related to its function as an innate immune checkpoint when expressed on tumor…”
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A Phase 1/2 Trial of Brief Androgen Suppression and Stereotactic Radiation Therapy (FASTR) for High-Risk Prostate Cancer
Published in International journal of radiation oncology, biology, physics (15-07-2015)“…Purpose To initiate a phase 1/2 trial to examine the tolerability of a condensed combined-modality protocol for high-risk prostate cancer. Methods and…”
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12
ecological limits of hydrologic alteration (ELOHA): a new framework for developing regional environmental flow standards
Published in Freshwater biology (01-01-2010)“…1. The flow regime is a primary determinant of the structure and function of aquatic and riparian ecosystems for streams and rivers. Hydrologic alteration has…”
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Stereotactic ablative radiotherapy for the comprehensive treatment of 1-3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial
Published in BMC cancer (05-05-2020)“…A recent randomized phase II trial evaluated stereotactic ablative radiotherapy (SABR) in a group of patients with a small burden of oligometastatic disease…”
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Quality of Life Outcomes After Stereotactic Ablative Radiation Therapy (SABR) Versus Standard of Care Treatments in the Oligometastatic Setting: A Secondary Analysis of the SABR-COMET Randomized Trial
Published in International journal of radiation oncology, biology, physics (01-12-2019)“…Randomized data assessing the longitudinal quality of life (QoL) impact of stereotactic ablative radiation therapy (SABR) in the oligometastatic setting are…”
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High-risk CT features for detection of local recurrence after stereotactic ablative radiotherapy for lung cancer
Published in Radiotherapy and oncology (01-10-2013)“…Abstract Background and purpose Early detection of local recurrences following stereotactic ablative radiotherapy (SABR) for lung cancer may allow for curative…”
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Does Peer Review of Radiation Plans Affect Clinical Care? A Systematic Review of the Literature
Published in International journal of radiation oncology, biology, physics (01-01-2017)“…Purpose Peer review is a recommended component of quality assurance in radiation oncology; however, it is resource-intensive and its effect on patient care is…”
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Failed Randomized Clinical Trials in Radiation Oncology: What Can We Learn?
Published in International journal of radiation oncology, biology, physics (01-08-2018)“…Randomized clinical trials (RCTs) are essential to evidence-based medicine, yet a significant proportion fail to be completed. In radiation oncology, factors…”
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Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
Published in Scientific reports (17-12-2021)“…Capillary endothelial cells of the human blood–brain barrier (BBB) express high levels of P-glycoprotein (P-gp, encoded by ABCB1 ) and ABCG2 (encoded by ABCG2…”
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Toward a CRISPR-based mouse model of Vhl -deficient clear cell kidney cancer: Initial experience and lessons learned
Published in Proceedings of the National Academy of Sciences - PNAS (08-10-2024)“…CRISPR is revolutionizing the ability to do somatic gene editing in mice for the purpose of creating new cancer models. Inactivation of the tumor suppressor…”
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Laser Microdissection Workflow for Isolating Nucleic Acids from Fixed and Frozen Tissue Samples
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…Laser Capture Microdissection has earned a permanent place among modern techniques connecting histology and molecular biology. Laser Capture Microdissection…”
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