Search Results - "Warner, Amanda N"
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Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover
Published in Molecular and cellular biology (30-01-2020)“…Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron degenerative disease. TDP-43 (TAR DNA-binding protein 43) and FUS (fused in sarcoma) are…”
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Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis
Published in Cells (Basel, Switzerland) (28-04-2022)“…The Golgi apparatus is at the center of protein processing and trafficking in normal cells. Under pathological conditions, such as in cancer, aberrant Golgi…”
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CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…The microenvironment that surrounds pancreatic ductal adenocarcinoma (PDAC) is profoundly desmoplastic and immunosuppressive. Understanding triggers of…”
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The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8 + cytotoxic T-cell response
Published in Genes & development (01-05-2022)“…One of the mechanisms by which cancer cells acquire hyperinvasive and migratory properties with progressive loss of epithelial markers is the…”
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Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis
Published in Cell reports (Cambridge) (27-09-2022)“…Lung cancer is a highly aggressive and metastatic disease responsible for approximately 25% of all cancer-related deaths in the United States. Using…”
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Circadian signaling in Homarus americanus: Region-specific de novo assembled transcriptomes show that both the brain and eyestalk ganglia possess the molecular components of a putative clock system
Published in Marine genomics (01-07-2018)“…Essentially all organisms exhibit recurring patterns of physiology/behavior that oscillate with a period of ~24-h and are synchronized to the solar day…”
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Molecular evidence for an intrinsic circadian pacemaker in the cardiac ganglion of the American lobster, Homarus americanus - Is diel cycling of heartbeat frequency controlled by a peripheral clock system?
Published in Marine genomics (01-10-2018)“…Whether cardiac output in decapod crustaceans is under circadian control has long been debated, with mixed evidence for and against the hypothesis. Moreover,…”
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