Search Results - "Warman, Anmol"
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Location bias contributes to functionally selective responses of biased CXCR3 agonists
Published in Nature communications (04-10-2022)“…Some G protein-coupled receptor (GPCR) ligands act as “biased agonists” that preferentially activate specific signaling transducers over others. Although GPCRs…”
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Deep Learning System Boosts Radiologist Detection of Intracranial Hemorrhage
Published in Curēus (Palo Alto, CA) (13-10-2022)“…Intracranial hemorrhage (ICH) requires emergent medical treatment for positive outcomes. While previous artificial intelligence (AI) solutions achieved rapid…”
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2900 Additional Training in Nutrition Helps Recruit More Patients for Nutritional Therapy in Inflammatory Bowel Disease (IBD)
Published in The American journal of gastroenterology (01-10-2019)“…INTRODUCTION: IBD is growing at an alarming rate from than 1 per100,000 in 1960s to 4.1 in 1980s in the western world. This sharp increase is unlikely to be…”
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4
Machine learning predictive models in neurosurgery: an appraisal based on the TRIPOD guidelines. Systematic review
Published in Neurosurgical focus (01-06-2023)“…In recent years, machine learning models for clinical prediction have become increasingly prevalent in the neurosurgical literature. However, little is known…”
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Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension
Published in American journal of respiratory and critical care medicine (15-05-2023)“…Chronic thromboembolic pulmonary hypertension (CTEPH) is a sequela of acute pulmonary embolism (PE) in which the PE remodels into a chronic scar in the…”
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Prevalence of Metabolic Syndrome and Type 2 Diabetes in Veterans With Nonalcoholic Fatty Liver Disease: 1026
Published in The American journal of gastroenterology (01-10-2018)“…Introduction: Non-alcoholic fatty liver disease (NAFLD) has become a public health crisis throughout the modern world. NAFLD can progress to fibrosis in what…”
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A deep learning method to identify and localize large‐vessel occlusions from cerebral digital subtraction angiography
Published in Journal of neuroimaging (01-05-2024)“…Background and purpose An essential step during endovascular thrombectomy is identifying the occluded arterial vessel on a cerebral digital subtraction…”
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8
Augmented reality in spine surgery - past, present, and future
Published in The spine journal (01-01-2024)“…Augmented reality (AR) is increasingly recognized as a valuable tool in spine surgery. Here we provides an overview of the key developments and technological…”
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181 Long Noncoding RNAs (lncRNAs) Are Different in Polyps of Obese and Lean Suggesting Different Pathophysiology
Published in The American journal of gastroenterology (01-10-2019)“…INTRODUCTION: Colorectal cancer is the third most cancer diagnosed in USA. Long noncoding RNAs (lncRNAs) are important orchestrators of essential biological…”
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Abstract 15386: Integrated Phosphoproteome and Transcriptome Analysis of Biased Agonists at CXCR3 Reveals Differential Cellular Outputs of Inflammation
Published in Circulation (New York, N.Y.) (17-11-2020)“…Background and ObjectiveG-protein-coupled receptors (GPCRs) are the most common cell surface receptor class and are known to influence nearly every biological…”
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Location Bias Contributes to Functionally Selective Responses of Biased CXCR3 Agonists to Regulate Inflammation
Published in The FASEB journal (01-05-2022)“…G Protein‐Coupled Receptors (GPCRs) represent the largest and most diverse family of cell receptors in the human genome and are targeted by ~35% of all…”
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12
External Validation of an Artificial Intelligence Device for Intracranial Hemorrhage Detection
Published in World neurosurgery (01-05-2023)“…Artificial intelligence applications have gained traction in the field of cerebrovascular disease by assisting in the triage, classification, and…”
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13
Concomitant Traumatic Brain Injury Delays Surgery in Patients With Traumatic Spinal Cord Injury
Published in Neurosurgery (10-01-2024)“…Growing evidence supports prompt surgical decompression for patients with traumatic spinal cord injury (tSCI). Rates of concomitant tSCI and traumatic brain…”
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14
Phosphorylation barcodes direct biased chemokine signaling at CXCR3
Published in Cell chemical biology (20-04-2023)“…G protein-coupled receptor (GPCR)-biased agonism, selective activation of certain signaling pathways relative to others, is thought to be directed by…”
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Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi and β‐arrestin complexes
Published in The FASEB journal (01-04-2020)“…Abstract only G‐protein‐coupled receptors (GPCRs) are the most common cell surface receptor class and influence nearly every biological process within a cell…”
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Changes in the Skin Microbiome Following Dermatological Procedures: A Scoping Review
Published in Applied Microbiology (Basel) (01-06-2024)“…The skin microbiome consists of bacteria, fungi, viruses, and mites, which play a crucial role in maintaining skin health and immune function. Imbalances in…”
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Biased agonists of the chemokine receptor CXCR3 differentially signal through Gα i :β-arrestin complexes
Published in Science signaling (22-03-2022)“…G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors and signal through the proximal effectors, G proteins and β-arrestins, to…”
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Noncanonical scaffolding of G αi and β-arrestin by G protein-coupled receptors
Published in Science (American Association for the Advancement of Science) (12-03-2021)“…Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) are common drug targets and canonically couple to specific G protein…”
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