Search Results - "Wargon, Victoria"

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer by Lanari, Claudia, Lamb, Caroline A, Fabris, Victoria T, Helguero, Luisa A, Soldati, Rocío, Bottino, María Cecilia, Giulianelli, Sebastián, Cerliani, Juan Pablo, Wargon, Victoria, Molinolo, Alfredo

“…More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). By contrast, most of the spontaneous,…”
Get full text

Novel, low cost, highly effective, handmade steroid pellets for experimental studies by Sahores, Ana, Luque, Guillermina M, Wargon, Victoria, May, María, Molinolo, Alfredo, Becu-Villalobos, Damasia, Lanari, Claudia, Lamb, Caroline A

“…The basic component of Silastic® glue (Dow Corning) used to prepare Silastic® pellets is polydimethylsiloxane. This compound is also present in other…”
Get full text

Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice by Polo, Maria Laura, Arnoni, Maria Victoria, Riggio, Marina, Wargon, Victoria, Lanari, Claudia, Novaro, Virginia

“…A significant proportion of breast cancer patients face failure of endocrine therapy due to the acquisition of endocrine resistance. We have explored…”
Get full text

Antiprogestins in breast cancer treatment: are we ready? by Lanari, Claudia, Wargon, Victoria, Rojas, Paola, Molinolo, Alfredo A

“…Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. It is accepted that breast cancer is not a…”
Get full text

Abstract 1315: DNMT and HDAC inhibitors resensitize resistant tumors to antiprogestin therapy in a mouse breast cancer model by Wargon, Victoria, Lanari, Claudia

“…Abstract Mouse mammary carcinomas induced by medroxyprogesterone acetate (MPA) are maintained by syngeneic transplantation and tumor variants with different…”
Get full text

Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1 by Abascal, María Florencia, Elia, Andrés, Alvarez, Michelle, Pataccini, Gabriela, Sequeira, Gonzalo, Riggio, Marina, Figueroa, Virginia, Lamb, Caroline A., Rojas, Paola A., Spengler, Eunice, Martínez‐Vazquez, Paula, Burruchaga, Javier, Liguori, Marcos, Sahores, Ana, Wargon, Victoria, Molinolo, Alfredo, Hewitt, Stephen, Lombes, Marc, Sartorius, Carol, Vanzulli, Silvia Inés, Giulianelli, Sebastián, Lanari, Claudia

“…Progesterone receptors (PRs) ligands are being tested in luminal breast cancer. There are mainly two PR isoforms, PRA and PRB, and their ratio (PRA/PRB) may be…”
Get full text

Inmunohistoquimica y expresion de receptores de estrogenos y progesterona en neoplasias mamarias malignas caninas en distintos estadios clinicos by Hermo, Guillermo, Soldati, Rocio, Wargon, Victoria, Scursoni, Alejandra, Lanari, Claudia, Gobello, Cristina

“…La técnica de inmunohistoquímica descrita por Walker y col. (1998) y Mote y col. (2001) es de utilidad para la determinación de receptores de estrógenos y de…”
Get full text

Estrogen Receptor Alpha Mediates Progestin-Induced Mammary Tumor Growth by Interacting with Progesterone Receptors at the Cyclin D1/MYC Promoters by GIULIANELLI, Sebastián, VAQUE, José P, SILVIO GUTKIND, J, LANARI, Claudia, SOLDATI, Rocio, WARGON, Victoria, VANZULLI, Silvia I, MARTINS, Rubén, ZEITLIN, Eduardo, MOLINOLO, Alfredo A, HELGUERO, Luisa A, LAMB, Caroline A

“…Synthetic progesterone used in contraception drugs (progestins) can promote breast cancer growth, but the mechanisms involved are unknown. Moreover, it remains…”
Get full text

Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters by Wargon, Victoria, Riggio, Marina, Giulianelli, Sebastián, Sequeira, Gonzalo R., Rojas, Paola, May, María, Polo, María L., Gorostiaga, María A., Jacobsen, Britta, Molinolo, Alfredo, Novaro, Virginia, Lanari, Claudia

“…There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the…”
Get full text

Abstract 1387: The ratio of progesterone receptor isoforms predicts progestin and antiprogestin response: Interaction of PR with AIB1 or SMRT by Riggio, Marina, Giulianelli, Sebastián, Wargon, Victoria, Novaro, Virginia, Lanari, Claudia

“…Abstract We have previously demonstrated in a mouse model of breast cancer that mammary carcinomas which are responsive to the antiprogestin mifepristone (MFP)…”
Get full text

Abstract 532: Differential expression of FGFR-1 and -2 in hormone responsive and resistant murine mammary carcinomas by Sahores, Ana, Guillardoy, Tomás, Wargon, Victoria, Lanari, Claudia, Lamb, Caroline

“…Abstract Fibroblast growth factor (FGF) receptors (FGFRs) are dysregulated in a number of developmental and neoplastic conditions. In human breast cancer…”
Get full text

Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas by Wargon, Victoria, Fernandez, Sandra V, Goin, Mercedes, Giulianelli, Sebastián, Russo, Jose, Lanari, Claudia

“…Most breast carcinomas that are estrogen receptor (ER) and progesterone receptor (PR) positive respond initially to an endocrine therapy, but over time, they…”
Get full text

Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia by Copsel, Sabrina, Bruzzone, Ariana, May, Maria, Beyrath, Julien, Wargon, Victoria, Cany, Jeannette, Russel, Frans G M, Shayo, Carina, Davio, Carlos

“…Less than a third of adults patients with acute myeloid leukemia (AML) are cured by current treatments, emphasizing the need for new approaches to therapy. We…”
Get full text

Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA / PRB ratio via AIB 1 or SMRT recruitment to the CCND 1 and MYC promoters by Wargon, Victoria, Riggio, Marina, Giulianelli, Sebastián, Sequeira, Gonzalo R., Rojas, Paola, May, María, Polo, María L., Gorostiaga, María A., Jacobsen, Britta, Molinolo, Alfredo, Novaro, Virginia, Lanari, Claudia

“…There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the…”
Get full text

Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas by Wargon, Victoria, Helguero, Luisa A., Bolado, Julieta, Rojas, Paola, Novaro, Virginia, Molinolo, Alfredo, Lanari, Claudia

“…To explore mechanisms related to hormone resistance, three resistant variants of the MPA mouse breast cancer tumor model with low levels of progesterone…”
Get full text

Expression and methylation status of female-predominant GH-dependent liver genes are modified by neonatal androgenization in female mice by Ramirez, Maria Cecilia, Zubeldía-Brenner, Lautaro, Wargon, Victoria, Ornstein, Ana María, Becu-Villalobos, Damasia

“…•Neonatal testosterone exposure partially masculinized the GH axis in female mice.•It evoked a defeminization of female predominant GH-dependent liver…”
Get full text

Abstract 1319: Early tumor regression after endocrine and kinase inhibitor treatments in mammary carcinomas with different hormonal requirements by Polo, Maria Laura, Riggio, Marina, Wargon, Victoria, Giulianelli, Sebastian, Vanzulli, Silvia I., Lanari, Claudia, Novaro, Virginia

“…Abstract Two-thirds of diagnosed breasts cancers express either estrogen receptors (ER), progesterone receptors (PR) or both. Unlike most experimental breast…”
Get full text

Abstract 4609: Therapeutic effects of pegylated doxorubicin liposomes in endocrine responsive and unresponsive murine mammary carcinomas by Vanzulli, Silvia, Bolado, Julieta, Soldati, Rocío, Wargon, Victoria, Luthy, Isabel, Colombo, Lucas, Molinolo, Alfredo, Lanari, Claudia

“…Abstract Doxorubicin is commonly used in the treatment of several cancers, including breast and ovarian cancers. In spite of the development of modern…”
Get full text

Gelation and structural characteristics of incompatible whey proteins/hydroxypropylmethylcellulose mixtures by Pérez, Oscar E., Wargon, Victoria, M.R. Pilosof, Ana

“…The influence of hydroxypropylmethycellulose (HPMC) on whey protein (WPC) gelling properties was studied under thermodynamic incompatibility conditions at…”
Get full text

Inhibition of mammary tumor growth by estrogens: is there a specific role for estrogen receptors alpha and beta by Soldati, Rocío, Wargon, Victoria, Cerliani, Juan Pablo, Giulianelli, Sebastián, Vanzulli, Silvia Inés, Gorostiaga, María Alicia, Bolado, Julieta, do Campo, Pablo, Molinolo, Alfredo, Vollmer, Günter, Lanari, Claudia

“…To evaluate the extent to which each estrogen receptor (ER) subtype contributes to the stimulation or to the inhibition of mammary tumor growth, we evaluated…”
Get full text