Search Results - "Wargent, E."

The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity by Wargent, E T, Zaibi, M S, Silvestri, C, Hislop, D C, Stocker, C J, Stott, C G, Guy, G W, Duncan, M, Di Marzo, V, Cawthorne, M A

“…Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric effects…”
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Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions by Fyfe, M. C. T, White, J. R, Taylor, A, Chatfield, R, Wargent, E, Printz, R. L, Sulpice, T, McCormack, J. G, Procter, M. J, Reynet, C, Widdowson, P. S, Wong-Kai-In, P

“…Aims/hypothesis We evaluated the insulinotropic and antihyperglycaemic actions of glucokinase activators (GKAs), especially through acute and subchronic…”
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Leanness in postnatally nutritionally programmed rats is associated with increased sensitivity to leptin and a melanocortin receptor agonist and decreased sensitivity to neuropeptide Y by Stocker, C J, Wargent, E T, Martin-Gronert, M S, Cripps, R L, O'Dowd, J F, Zaibi, M S, Cottrell, E C, Mercer, J G, Duncan, J S, Cawthorne, M A, Ozanne, S E, Arch, J R S

“…Background: Pups of normally nourished dams that are cross-fostered after birth to dams fed a low-protein (8% by weight) diet (postnatal low protein (PLP))…”
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A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice by Ngala, R. A., Stocker, C. J., Roy, A. G., Hislop, D., Wargent, E., Bell, R., Hassall, D. G., Harling, J. D., Billin, A. N., Willson, T. M., Arch, J. R. S., Cawthorne, M. A.

“…Aim: We investigated how GW800644, the first pharmacologically selective murine peroxisome proliferator‐activated receptor δ (PPARδ) agonist, affects energy…”
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Rapid stimulation of cyclic AMP production by aldosterone in rat inner medullary collecting ducts by Sheader, EA, Wargent, ET, Ashton, N, Balment, RJ

“…Aldosterone stimulates sodium transport in the inner medullary collecting duct (IMCD) via the classic genomic pathway, but it is not known whether it also acts…”
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Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation by STOCKER, C, O'DOWD, J, MORTON, N. M, WARGENT, E, SENNITT, M. V, HISLOP, D, GLUND, S, SECKL, J. R, ARCH, J. R. S, CAWTHORNE, M. A

“…To investigate whether administration of leptin to rats during pregnancy and lactation affects placental 11beta-hydroxysteroid dehydrogenase (11beta-HSD2)…”
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P1-109 Patterns of postnatal growth impact on the early life programming of energy balance by Stocker, C, Wargent, E, O'Dowd, J, Ngala, R, Carling, D, Arch, J, Cawthorne, M

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Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone by Wargent, E., Stocker, C., Augstein, P., Heinke, P., Meyer, A., Hoffmann, T., Subramanian, A., Sennitt, M. V., Demuth, H.-U., Arch, J. R. S., Cawthorne, M. A.

“…Aim:  The aim of this study was to investigate the effect of long‐term treatment with the dipeptidyl peptidase inhibitor P32/98 and its combination with…”
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Separate receptors mediate oxytocin and vasopressin stimulation of cAMP in rat inner medullary collecting duct cells by Wargent, E. T., Burgess, W. J., Laycock, J. F., Balment, R. J.

“…The two neurohypophysial hormones arginine vasopressin (AVP) and oxytocin have actions in the inner medullary collecting duct (IMCD) where both peptides induce…”
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Chloroquine inhibits arginine vasopressin production in isolated rat inner medullary segments induced cAMP collecting duct by Musabayane, C T, Wargent, E T, Balment, R J

“…Previous studies showed that acute chloroquine administration increases plasma arginine vasopressin (AVP) concentration in the rat without influencing urine…”
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Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3β on a muscle-specific promoter by Pearce, Nigel J., Arch, Jonathan R.S., Clapham, John C., Coghlan, Matthew P., Corcoran, Stacey L., Lister, Carolyn A., Llano, Andrea, Moore, Gary B., Murphy, Gregory J., Smith, Stephen A., Taylor, Colleen M., Yates, John W., Morrison, Alastair D., Harper, Alexander J., Roxbee-Cox, Lynne, Abuin, Alejandro, Wargent, Ed, Holder, Julie C.

“…Glycogen synthase kinase-3 (GSK-3) protein levels and activity are elevated in skeletal muscle in type 2 diabetes, and inversely correlated with both glycogen…”
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The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity by Wargent, E T, Zaibi, M S, Silvestri, C, Hislop, D C, Stocker, C J, Stott, C G, Guy, G W, Duncan, M, Di Marzo, V, Cawthorne, M A

“…Background: Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric…”
Get full text

The cannabinoid [Delta]9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity by Wargent, E T, Zaibi, M S, Silvestri, C, Hislop, D C, Stocker, C J, Stott, C G, Guy, G W, Duncan, M, Di Marzo, V, Cawthorne, M A

“…Background:Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric…”
Get full text