Search Results - "Ware, Sarah A"

Cell-free DNA levels associate with COPD exacerbations and mortality by Ware, Sarah A, Kliment, Corrine R, Giordano, Luca, Redding, Kevin M, Rumsey, William L, Bates, Stewart, Zhang, Yingze, Sciurba, Frank C, Nouraie, S Mehdi, Kaufman, Brett A

“…Good biological indicators capable of predicting chronic obstructive pulmonary disease (COPD) phenotypes and clinical trajectories are lacking. Because nuclear…”
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Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD by Giordano, Luca, Gregory, Alyssa D, Pérez Verdaguer, Mireia, Ware, Sarah A, Harvey, Hayley, DeVallance, Evan, Brzoska, Tomasz, Sundd, Prithu, Zhang, Yingze, Sciurba, Frank C, Shapiro, Steven D, Kaufman, Brett A

“…Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary disease (COPD). The present study aimed to elucidate whether mtDNA is…”
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A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations by Sturm, Gabriel, Monzel, Anna S., Karan, Kalpita R., Michelson, Jeremy, Ware, Sarah A., Cardenas, Andres, Lin, Jue, Bris, Céline, Santhanam, Balaji, Murphy, Michael P., Levine, Morgan E., Horvath, Steve, Belsky, Daniel W., Wang, Shuang, Procaccio, Vincent, Kaufman, Brett A., Hirano, Michio, Picard, Martin

“…Aging is a process of progressive change. To develop biological models of aging, longitudinal datasets with high temporal resolution are needed. Here we report…”
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An automated, high-throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma by Ware, Sarah A., Desai, Nikita, Lopez, Mabel, Leach, Daniel, Zhang, Yingze, Giordano, Luca, Nouraie, Mehdi, Picard, Martin, Kaufman, Brett A.

“…Progress in the study of circulating, cell-free nuclear DNA (ccf-nDNA) in cancer detection has led to the development of noninvasive clinical diagnostic tests…”
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Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging by Bobba-Alves, Natalia, Sturm, Gabriel, Lin, Jue, Ware, Sarah A., Karan, Kalpita R., Monzel, Anna S., Bris, Céline, Procaccio, Vincent, Lenaers, Guy, Higgins-Chen, Albert, Levine, Morgan, Horvath, Steve, Santhanam, Balaji S., Kaufman, Brett A., Hirano, Michio, Epel, Elissa, Picard, Martin

“…Stress triggers anticipatory physiological responses that promote survival, a phenomenon termed allostasis. However, the chronic activation of energy-dependent…”
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OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases by Sturm, Gabriel, Karan, Kalpita R., Monzel, Anna S., Santhanam, Balaji, Taivassalo, Tanja, Bris, Céline, Ware, Sarah A., Cross, Marissa, Towheed, Atif, Higgins-Chen, Albert, McManus, Meagan J., Cardenas, Andres, Lin, Jue, Epel, Elissa S., Rahman, Shamima, Vissing, John, Grassi, Bruno, Levine, Morgan, Horvath, Steve, Haller, Ronald G., Lenaers, Guy, Wallace, Douglas C., St-Onge, Marie-Pierre, Tavazoie, Saeed, Procaccio, Vincent, Kaufman, Brett A., Seifert, Erin L., Hirano, Michio, Picard, Martin

“…Patients with primary mitochondrial oxidative phosphorylation (OxPhos) defects present with fatigue and multi-system disorders, are often lean, and die…”
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Molecular evidence for the export of terrigenous organic matter to the north Gulf of Mexico by solid-state 13C NMR and Fourier transform ion cyclotron resonance mass spectrometry of humic acids by Ware, Sarah A., Hartman, Blaine E., Waggoner, Derek C., Vaughn, Derrick R., Bianchi, Thomas S., Hatcher, Patrick G.

“…Sediment samples along a transect extending from the Mississippi River Birdsfoot Delta to the Mississippi Canyon on the Louisiana continental shelf were…”
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