Search Results - "Wardyn, Joanna"

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways by Wardyn, Joanna D, Ponsford, Amy H, Sanderson, Christopher M

“…In most tissues, cells are exposed to frequent changes in levels of oxidative stress and inflammation. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and…”
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Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer by Hoppe, Michal M, Jaynes, Patrick, Wardyn, Joanna D, Upadhyayula, Sai Srinivas, Tan, Tuan Zea, Lie, Stefanus, Lim, Diana G Z, Pang, Brendan N K, Lim, Sherlly, P S Yeong, Joe, Karnezis, Anthony, Chiu, Derek S, Leung, Samuel, Huntsman, David G, Sedukhina, Anna S, Sato, Ko, Topp, Monique D, Scott, Clare L, Choi, Hyungwon, Patel, Naina R, Brown, Robert, Kaye, Stan B, Pitt, Jason J, Tan, David S P, Jeyasekharan, Anand D

“…Early relapse after platinum chemotherapy in epithelial ovarian cancer (EOC) portends poor survival. A‐priori identification of platinum resistance is…”
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PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production by Srinivas, Upadhyayula S., Tay, Norbert S. C., Jaynes, Patrick, Anbuselvan, Akshaya, Ramachandran, Gokula K., Wardyn, Joanna D., Hoppe, Michal M., Hoang, Phuong Mai, Peng, Yanfen, Lim, Sherlly, Lee, May Yin, Peethala, Praveen C., An, Omer, Shendre, Akshay, Tan, Bryce W. Q., Jemimah, Sherlyn, Lakshmanan, Manikandan, Hu, Longyu, Jakhar, Rekha, Sachaphibulkij, Karishma, Lim, Lina H. K., Pervaiz, Shazib, Crasta, Karen, Yang, Henry, Tan, Patrick, Liang, Chao, Ho, Lena, Khanchandani, Vartika, Kappei, Dennis, Yong, Wei Peng, Tan, David S. P., Bordi, Matteo, Campello, Silvia, Tam, Wai Leong, Frezza, Christian, Jeyasekharan, Anand D.

“…Inhibitors of the mitotic kinase PLK1 yield objective responses in a subset of refractory cancers. However, PLK1 overexpression in cancer does not correlate…”
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Low cost production of 3D-printed devices and electrostimulation chambers for the culture of primary neurons by Wardyn, Joanna D, Sanderson, Chris, Swan, Laura E, Stagi, Massimiliano

“…The analysis of primary neurons is a basic requirement for many areas of neurobiology. However, the range of commercial systems available for culturing primary…”
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Generation and characterization of a lysosomally targeted, genetically encoded Ca(2+)-sensor by McCue, Hannah V, Wardyn, Joanna D, Burgoyne, Robert D, Haynes, Lee P

“…Distinct spatiotemporal Ca2+ signalling events regulate fundamental aspects of eukaryotic cell physiology. Complex Ca2+ signals can be driven by release of…”
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T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival by de Mel, Sanjay, Mustafa, Nurulhuda, Selvarajan, Viknesvaran, Azaman, Muhammad Irfan, Jaynes, Patrick William, Venguidessane, Shruthi, Phuong, Hoang Mai, Alnaseri, Zubaida Talal, Phyu, The, Girard, Louis-Pierre, Chng, Wee Joo, Wardyn, Joanna, Li, Ying, An, Omer, Yang, Henry, Ng, Siok Bian, Jeyasekharan, Anand D

“…B-cell receptor (BCR) signalling is critical for the survival of B-cell lymphomas and is a therapeutic target of drugs such as Ibrutinib. However, the role of…”
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Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production by Srinivas, Upadhyayula S., Tay, Norbert S. C., Jaynes, Patrick, Anbuselvan, Akshaya, Ramachandran, Gokula K., Wardyn, Joanna D., Hoppe, Michal M., Hoang, Phuong Mai, Peng, Yanfen, Lim, Sherlly, Lee, May Yin, Peethala, Praveen C., An, Omer, Shendre, Akshay, Tan, Bryce W. Q., Jemimah, Sherlyn, Lakshmanan, Manikandan, Hu, Longyu, Jakhar, Rekha, Sachaphibulkij, Karishma, Lim, Lina H. K., Pervaiz, Shazib, Crasta, Karen, Yang, Henry, Tan, Patrick, Liang, Chao, Ho, Lena, Khanchandani, Vartika, Kappei, Dennis, Yong, Wei Peng, Tan, David S. P., Bordi, Matteo, Campello, Silvia, Tam, Wai Leong, Frezza, Christian, Jeyasekharan, Anand D.

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A Robust Protocol for CRISPR-Cas9 Gene Editing in Human Suspension Cell Lines by Wardyn, Joanna D, Chan, Allison S Y, Jeyasekharan, Anand D

“…The implementation of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 systems in mammalian cells has sparked an exciting new era in…”
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Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma by Wardyn, Joanna D., Hoppe, Michal M., Chan, Allison S., Li, Jia, An, Omer, Venguidessane, Shruthi, Sheng, Dominic P., Yang, Henry, Yeo, Gene W., Hodson, Daniel J., Harris, Reuben S., Jeyasekharan, Anand D.

“…Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A…”
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mRNAid, an open-source platform for therapeutic mRNA design and optimization strategies by Vostrosablin, Nikita, Lim, Shuhui, Gopal, Pooja, Brazdilova, Kveta, Parajuli, Sushmita, Wei, Xiaona, Gromek, Anna, Prihoda, David, Spale, Martin, Muzdalo, Anja, Greig, Jamie, Yeo, Constance, Wardyn, Joanna, Mejzlik, Petr, Henry, Brian, Partridge, Anthony W, Bitton, Danny A

“…Abstract Recent COVID-19 vaccines unleashed the potential of mRNA-based therapeutics. A common bottleneck across mRNA-based therapeutic approaches is the rapid…”
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Investigating the Molecular Mechanism of Crosstalk Between NF-κB and Nrf2 Signalling Pathways by Wardyn, Joanna Dorota

“…In order to maintain tissue homeostasis, cells must respond swiftly to inflammatory and oxidative challenges, ensuring appropriate processes are sequentially…”
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