Search Results - "Wardle, Greg"
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Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
Published in Cell (02-04-2010)“…RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein…”
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Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
Published in Nature (London) (08-10-2009)“…The slicer activity of the RNA-induced silencing complex resides within its Argonaute (Ago) component, in which the PIWI domain provides the catalytic residues…”
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Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
Published in Immunity (Cambridge, Mass.) (17-07-2009)“…Antiviral immunity is triggered by immunorecognition of viral nucleic acids. The cytosolic helicase RIG-I is a key sensor of viral infections and is activated…”
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PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins
Published in Journal of visualized experiments (02-07-2010)“…RNA transcripts are subjected to post-transcriptional gene regulation by interacting with hundreds of RNA-binding proteins (RBPs) and microRNA-containing…”
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PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins
Published in Methods in enzymology (2014)“…We recently developed a protocol for the transcriptome-wide isolation of RNA recognition elements readily applicable to any protein or ribonucleoprotein…”
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Practical Synthesis of Cytidine-5-Carboxamide-Modified Nucleotide Reagents
Published in Nucleosides, nucleotides & nucleic acids (04-03-2015)“…Chemically-modified derivatives of cytidine, bearing a 5-(N-substituted-carboxamide) functional group, are new reagents for use in aptamer discovery via the…”
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Molecular diagnostics for monitoring contaminants in algal cultivation
Published in Algal research (Amsterdam) (01-04-2014)“…There is currently great interest in mass cultivation of microalgae for production of fuels and other high value products. Since algae have not previously been…”
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Nucleation, propagation and cleavage of target RNAs in argonaute silencing complexes
Published in Nature (London) (08-10-2009)“…The slicer activity of the RNA-induced silencing complex resides within its Argonaute (Ago) component, whose PIWI domain provides the catalytic residues…”
Get full text
Journal Article -
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PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
Published in Journal of visualized experiments (02-07-2010)Get full text
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