Search Results - "Warda, Mohamad"
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Unlocking the mysteries of VLDL: exploring its production, intracellular trafficking, and metabolism as therapeutic targets
Published in Lipids in health and disease (12-01-2024)“…Reducing circulating lipid levels is the centerpiece of strategies for preventing and treating atherosclerotic cardiovascular disease (ASCVD). Despite many…”
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Differential Glycosylation and Modulation of Camel and Human HSP Isoforms in Response to Thermal and Hypoxic Stresses
Published in International journal of molecular sciences (30-01-2018)“…Increased expression of heat shock proteins (HSPs) following heat stress or other stress conditions is a common physiological response in almost all living…”
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A combined administration of GABA agonist and L-histidine synergistically alleviates obesity-induced neuro-lipotoxicity and distorted metabolic transcriptome
Published in Scientific African (01-06-2024)“…Obesity stands as a pervasive and significant global health issue, with a lack of definitive and curative therapeutic solutions currently available. Here we…”
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ER Stress in COVID-19 and Parkinson's Disease: In Vitro and In Silico Evidences
Published in Brain sciences (16-04-2022)“…The outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signifies a serious worldwide concern to public health. Both…”
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Isolation and characterization of heparan sulfate from various murine tissues
Published in Glycoconjugate journal (01-11-2006)“…Heparan sulfate (HS), is a proteoglycan (PG) found both in the extracellular matrix and on cell surface. It may represent one of the most biologically…”
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The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial
Published in Journal of clinical pharmacy and therapeutics (01-12-2022)“…What is known and objective Tietze syndrome is a rare form of chest wall costochondritis with joint swelling which can cause significant chest pain and decline…”
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LC–MS/MS characterization, anti‐inflammatory effects and antioxidant activities of polyphenols from different tissues of Korean Petasites japonicus (Meowi)
Published in Biomedical chromatography (01-12-2017)“…The Korean Petasites japonicus is a perennial plant used in folk medicine as a remedy for many diseases and popularly consumed as spring greens. Ten…”
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Synergistic renoprotective effect of a compiled branched-chain amino acids and Cymbopogon schoenanthus extract against experimentally induced oxido-nitrosative renal insult
Published in Asian Pacific journal of tropical medicine (01-05-2018)“…Objective: To better investigate the protective role of branched-chain amino acids (BCAAs) and Cymbopogon schoenanthus (CS) extract against the potassium…”
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A study on IL8RB gene polymorphism as a potential immuno-compromised adherent in exaggeration of parenteral and mammo-crine oxidative stress during mastitis in buffalo
Published in Journal of advanced research (01-11-2017)“…[Display omitted] The genetic markers in inflammatory responses during mastitis afford a reasonable way for improving milk production in the Egyptian buffalo…”
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Proteomics of old world camelid (Camelus dromedarius): Better understanding the interplay between homeostasis and desert environment
Published in Journal of advanced research (01-03-2014)“…Life is the interplay between structural–functional integrity of biological systems and the influence of the external environment. To understand this…”
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Nitric oxide-cGMP-protein kinase G signaling pathway induces anoxic preconditioning through activation of ATP-sensitive K+ channels in rat hearts
Published in American journal of physiology. Heart and circulatory physiology (01-05-2006)“…Nitric oxide (NO) plays an important role in anoxic preconditioning to protect the heart against ischemia-reperfusion injuries. The present work was performed…”
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Mitochondrial Ca2+-activated K+ channels more efficiently reduce mitochondrial Ca2+ overload in rat ventricular myocytes
Published in American journal of physiology. Heart and circulatory physiology (01-07-2007)“…We investigated the role of the mitochondrial ATP-sensitive K(+) (K(ATP)) channel, the mitochondrial big-conductance Ca(2+)-activated K(+) (BK(Ca)) channel,…”
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Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery
Published in PloS one (20-08-2012)“…Beta adrenergic overstimulation may increase the vascular damage and stroke. However, the underlying mechanisms of beta adrenergic overstimulation in…”
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Structural characterization of human liver heparan sulfate
Published in Biochimica et biophysica acta (18-01-2005)“…The isolation, purification and structural characterization of human liver heparan sulfate are described. 1H-NMR spectroscopy demonstrates the purity of this…”
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Increased Inhibition of Inward Rectifier K+ Channels by Angiotensin II in Small-Diameter Coronary Artery of Isoproterenol-Induced Hypertrophied Model
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2007)“…OBJECTIVE—We investigated the effects of angiotensin II (Ang II) on inward rectifier K (Kir) channels in small-diameter coronary arterial smooth muscle cells…”
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Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells
Published in Biochemical and biophysical research communications (24-03-2006)“…We examined the effects of the protein kinase A (PKA) inhibitor H-89 on voltage-dependent K(+) (K(V)) currents in freshly isolated rabbit coronary arterial…”
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The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cells
Published in Biochemical and biophysical research communications (24-02-2006)“…The effects of the protein kinase A (PKA) inhibitor H-89 on ATP-sensitive K+ (KATP) and inward rectifier K+ (Kir) currents were examined in rabbit coronary…”
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In Silico Elucidation of the Binding Mechanisms and Molecular Dynamics of Oroxylin A -2,3-Dioxygenase Interaction: An Insight into Therapeutic Potentiation of Quercetin’s Cardioprotection
Published in Recent Trends in Pharmacology (03-05-2024)“…Elucidating the intricate interplay between enzymes and natural compounds is essential for designing therapeutic strategies. This study employs advanced…”
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Direct modulation of Ca2+ -activated K+ current by H-89 in rabbit coronary arterial smooth muscle cells
Published in Vascular pharmacology (01-02-2007)“…Abstract The effects of H-89, a potent and selective inhibitor of protein kinase A (PKA) on Ca2+ -activated K+ (BKCa ) channels in coronary arterial smooth…”
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