Search Results - "Ward, W F"

Control of radiation-induced pneumopathy and lung fibrosis by angiotensin-converting enzyme inhibitors and an angiotensin II type 1 receptor blocker by Molteni, J. E. Moulder, E. F. Cohen, W. F. Ward, B. L. Fish, J. M. Taylor, L. F. Wolfe, L. Brizio-Molteni, P. Veno, A.

“…Purpose : This report summarizes our experiences on the protective effect of angiotensin-converting enzyme (ACE) inhibitors, especially captopril and an…”
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Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats by Volpert, O V, Ward, W F, Lingen, M W, Chesler, L, Solt, D B, Johnson, M D, Molteni, A, Polverini, P J, Bouck, N P

“…Captopril, an inhibitor of angiotensin converting enzyme, is widely used clinically to manage hypertension and congestive heart failure. Here captopril is…”
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Alteration of Rat Liver 20S Proteasome Activities by Age and Food Restriction by Shibatani, Toru, Nazir, Milady, Ward, Walter F.

“…The effects of age and food restriction on proteasome function in rat liver supernatant (100,000 × g) were investigated. The cellular level of the proteasome…”
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KGF facilitates repair of radiation-induced DNA damage in alveolar epithelial cells by Takeoka, M, Ward, W F, Pollack, H, Kamp, D W, Panos, R J

“…Administration of exogenous keratinocyte growth factor (KGF) prevents or attenuates several forms of oxidant-mediated lung injury. Because DNA damage in…”
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Captopril preserves function and ultrastructure in experimental radiation nephropathy by Cohen, E P, Molteni, A, Hill, P, Fish, B L, Ward, W F, Moulder, J E, Carone, F A

“…Captopril protects rat lung from radiation-induced pneumonitis and fibrosis and preserves function and survival in experimental radiation nephropathy. This…”
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Effect of Aging and Caloric Restriction on the Mitochondrial Proteome by Chang, Jinsook, Cornell, John E., Van Remmen, Holly, Hakala, Kevin, Ward, Walter F., Richardson, Arlan

“…The rat mitochondrial proteome was analyzed using two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), and proteins altered by age or caloric…”
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Phenylarsine oxide inhibition of endocytosis: effects on asialofetuin internalization by Gibson, A E, Noel, R J, Herlihy, J T, Ward, W F

“…The aim of this work was to establish to what extent the concentrations over which phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular…”
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Radiation Pneumonitis in Rats and Its Modification by the Angiotensin-Converting Enzyme Inhibitor Captopril Evaluated by High-Resolution Computed Tomography by Ward, William F., Lin, Pei-Jan Paul, Wong, Ping S., Behnia, Rahim, Jalali, Nasser

“…Adult male Sprague-Dawley rats were irradiated to the right hemithorax with a range of total doses delivered in 10 equal daily fractions of 4 MeV X rays. Half…”
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Captopril inhibits proliferation of human lung fibroblasts in culture: a potential antifibrotic mechanism by Nguyen, L, Ward, W F, Ts'ao, C H, Molteni, A

“…The angiotensin converting enzyme (ACE) inhibitor captopril, a free-thiol compound used widely as an antihypertensive agent, also inhibits radiation-induced…”
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Mechanism of captopril toxicity to a human mammary ductal carcinoma cell line in the presence of copper by SMALL, W. JR, MOLTENI, A, KIM, Y. T, TAYLOR, J. M, TS'AO, C.-H, WARD, W. F

“…Captopril (D-3-mercapto-2-methylpropanoyl-L-proline) is an angiotensin converting enzyme (ACE) inhibitor, used widely in the treatment of hypertension and…”
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Effect of Age and Food Restriction on Alkaline Protease Activity in Rat Liver by Shibatani, Toru, Ward, Walter F.

“…The effect of age and food restriction on the hepatic alkaline protease activity of 100,000 × g supernatant has been investigated using 7-, 16-, and…”
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Annexin I in fibrotic rat lung and cultured lung fibroblasts following irradiation by TS'AO, C, WARD, W. F, TSAO, F. H. C, TAYLOR, J. M, MOLTENI, A

“…Radiation-induced lung fibrosis is a result of collagen accumulation in the interstitium, partly due to increased collagen synthesis by fibroblasts. One…”
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Captopril modulates hormone receptor concentration and inhibits proliferation of human mammary ductal carcinoma cells in culture by SMALL, W. JR, MOLTENI, A, KIM, Y. T, TAYLOR, J. M, CHEN, Z, WARD, W. F

“…The present study evaluated the effect of the angiotensin converting enzyme (ACE) inhibitor captopril on estrogen (ER) and progesterone (PR) receptor…”
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Radiation pneumotoxicity in rats: modification by inhibitors of angiotensin converting enzyme by Ward, W F, Molteni, A, Ts'ao, C H, Kim, Y T, Hinz, J M

“…The present study determined whether inhibitors of angiotensin converting enzyme (ACE) can ameliorate radiation-induced pulmonary endothelial dysfunction and…”
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Captopril reduces collagen and mast cell accumulation in irradiated rat lung by Ward, W F, Molteni, A, Ts'ao, C H, Hinz, J M

“…The angiotensin converting enzyme inhibitor captopril ameliorates radiation-induced pulmonary endothelial dysfunction in rats. The present study determined…”
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A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA by Hamilton, M L, Guo, Z, Fuller, C D, Van Remmen, H, Ward, W F, Austad, S N, Troyer, D A, Thompson, I, Richardson, A

“…A major controversy in the area of DNA biochemistry concerns the actual in vivo levels of oxidative damage in DNA. We show here that 8-oxo-2-deoxyguanosine…”
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Evidence for Two Patterns of Inheritance of Sensitivity to Induction of Lung Fibrosis in Mice by Radiation, One of Which Involves Two Genes by Franko, Allan J., Sharplin, Janet, Ward, William F., Taylor, Joann M.

“…We showed previously that autosomal recessive determinants control the development of pulmonary fibrosis in mice during the early and late phases after…”
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Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine by Molteni, A, Ward, W F, Ts'ao, C H, Solliday, N H, Dunne, M

“…The purpose of this study was to determine whether Captopril (an angiotensin converting enzyme inhibitor) or D-penicillamine (an inhibitor of collagen…”
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Radiation-Induced Endothelial Dysfunction and Fibrosis in Rat Lung: Modification by the Angiotensin Converting Enzyme Inhibitor CL242817 by Ward, William F., Molteni, Agostino, Chung-hsin Ts'ao

“…The purpose of this study was to evaluate the angiotensin converting enzyme (ACE) inhibitor CL242817 as a modifier of radiation-induced pulmonary endothelial…”
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The Genetic Basis of Strain-Dependent Differences in the Early Phase of Radiation Injury in Mouse Lung by Franko, Allan J., Sharplin, Janet, Ward, William F., Hinz, Joann M.

“…Substantial differences between mouse strains have been reported in the lesions present in the lung during the early phase of radiation injury. Some strains…”
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