Search Results - "Ward, Thomas Ward"

Artificial Metalloenzymes Based on the Biotin−Avidin Technology: Enantioselective Catalysis and Beyond by Ward, Thomas R

“…Artificial metalloenzymes are created by incorporating an organometallic catalyst within a host protein. The resulting hybrid can thus provide access to the…”
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Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities by Heinisch, Tillmann, Ward, Thomas R

“…The biotin–streptavidin technology offers an attractive means to engineer artificial metalloenzymes (ArMs). Initiated over 50 years ago by Bayer and Wilchek,…”
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Palladium-Catalyzed Heck Cross-Coupling Reactions in Water: A Comprehensive Review by Christoffel, Fadri, Ward, Thomas R.

“…Palladium-catalyzed cross-coupling reactions have emerged as one of the most versatile tools in organic chemistry. Extensive efforts were made to adapt these…”
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Recent Advances in the Palladium Catalyzed Suzuki–Miyaura Cross-Coupling Reaction in Water by Chatterjee, Anamitra, Ward, Thomas R.

“…The palladium-catalyzed Suzuki–Miyaura cross-coupling reaction of organic halides with boronic acids is one of the most versatile methods for the synthesis of…”
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Computer vision in surgery by Ward, Thomas M., Mascagni, Pietro, Ban, Yutong, Rosman, Guy, Padoy, Nicolas, Meireles, Ozanan, Hashimoto, Daniel A.

“…The fields of computer vision (CV) and artificial intelligence (AI) have undergone rapid advancements in the past decade, many of which have been applied to…”
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Understanding an evolving pandemic: An analysis of the clinical time delay distributions of COVID-19 in the United Kingdom by Ward, Thomas, Johnsen, Alexander

“…Understanding and monitoring the epidemiological time delay dynamics of SARS-CoV-2 infection provides insights that are key to discerning changes in the…”
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Artificial Metalloenzymes on the Verge of New-to-Nature Metabolism by Jeschek, Markus, Panke, Sven, Ward, Thomas R.

“…Residing at the interface of chemistry and biotechnology, artificial metalloenzymes (ArMs) offer an attractive technology to combine the versatile reaction…”
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Bioorthogonal strategies for the in vivo synthesis or release of drugs by Lozhkin, Boris, Ward, Thomas R.

“…[Display omitted] The site-specific delivery of antitumor agents is a rapidly developing field that relies on prodrug activation and uncaging strategies. For…”
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Droplet Microfluidics and Directed Evolution of Enzymes: An Intertwined Journey by Stucki, Ariane, Vallapurackal, Jaicy, Ward, Thomas R., Dittrich, Petra S.

“…Evolution is essential to the generation of complexity and ultimately life. It relies on the propagation of the properties, traits, and characteristics that…”
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Directed evolution of artificial metalloenzymes for in vivo metathesis by Jeschek, Markus, Reuter, Raphael, Heinisch, Tillmann, Trindler, Christian, Klehr, Juliane, Panke, Sven, Ward, Thomas R.

“…An artificial metalloenzyme is compartmentalized and evolved in vivo for olefin metathesis—an archetypal organometallic reaction without equivalent in nature;…”
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The dangerous few: Taking seriously prison abolition and its skeptics by Frampton, Thomas Ward

“…Prison abolition, in the span of just a few short years, has established a foothold in elite criminal legal discourse. But the basic question of how…”
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Functional and morphological adaptation in DNA protocells via signal processing prompted by artificial metalloenzymes by Samanta, Avik, Sabatino, Valerio, Ward, Thomas R., Walther, Andreas

“…For life to emerge, the confinement of catalytic reactions within protocellular environments has been proposed to be a decisive aspect to regulate chemical…”
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Expectancy-Value Models for the STEM Persistence Plans of Ninth-Grade, High-Ability Students: A Comparison Between Black, Hispanic, and White Students by Andersen, Lori, Ward, Thomas J

“…Group differences in the effects of the expectancies and values that high-ability students have for science and mathematics on plans to persist in science,…”
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Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions by Hyster, Todd K., Ward, Thomas R.

“…Artificial metalloenzymes have received increasing attention over the last decade as a possible solution to unaddressed challenges in synthetic organic…”
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Recent advances in the design and optimization of artificial metalloenzymes by Morita, Iori, Ward, Thomas R.

“…Embedding a catalytically competent transition metal into a protein scaffold affords an artificial metalloenzyme (ArM). Such hybrid catalysts display features…”
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Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Enzymatic Cascades and Directed Evolution by Liang, Alexandria Deliz, Serrano-Plana, Joan, Peterson, Ryan L, Ward, Thomas R

“…Conspectus Artificial metalloenzymes (ArMs) result from anchoring a metal-containing moiety within a macromolecular scaffold (protein or oligonucleotide). The…”
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Recent achievments in the design and engineering of artificial metalloenzymes by Dürrenberger, Marc, Ward, Thomas R

“…•Artificial metalloenzymes result from incorporation of a metal cofactor in a protein.•These biohybrids catalyze abiotic transformations.•Artificial…”
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Artificial Metalloenzymes: Challenges and Opportunities by Davis, Holly J, Ward, Thomas R

“…Artificial metalloenzymes (ArMs) result from the incorporation of an abiotic metal cofactor within a protein scaffold. From the earliest techniques of…”
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In vivo catalyzed new-to-nature reactions by Rebelein, Johannes G, Ward, Thomas R

“…Bioorthogonal chemistry largely relies on the use of abiotic metals to catalyze new-to-nature reactions in living systems. Over the past decade, metal…”
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Artificial Metalloenzymes: Reaction Scope and Optimization Strategies by Schwizer, Fabian, Okamoto, Yasunori, Heinisch, Tillmann, Gu, Yifan, Pellizzoni, Michela M, Lebrun, Vincent, Reuter, Raphael, Köhler, Valentin, Lewis, Jared C, Ward, Thomas R

“…The incorporation of a synthetic, catalytically competent metallocofactor into a protein scaffold to generate an artificial metalloenzyme (ArM) has been…”
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