Search Results - "Ward, PA"

Adhesion molecules and inflammatory injury by Albelda, S M, Smith, C W, Ward, P A

“…Neutrophil-endothelial cell interactions are mediated by interacting sets of cell adhesion molecules (CAMs) and chemoattractant/activator molecules to form an…”
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Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo by Vaporciyan, Ara A., DeLisser, Horace M., Yan, Horng-Chin, Mendiguren, Ignacio I., Thom, Stephen R., Jones, Michael L., Ward, Peter A., Albelda, Steven M.

“…During inflammation, neutrophils migrate from the vascular lumen into extravascular sites. In vitro assays have suggested that platelet-endothelial cell…”
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Study of an adenosine A1 receptor agonist on trigeminally evoked dural blood vessel dilation in the anaesthetized rat by Honey, A C, Bland-Ward, P A, Connor, H E, Feniuk, W, Humphrey, P P A

“…The purpose of this study was to use intravital microscopy to determine the effect of a selective adenosine A1 receptor agonist, GR79236 (1, 3 and 10 microg/kg…”
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Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions by Fantone, J C, Ward, P A

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The dark side of C5a in sepsis by Ward, Peter A

“…Sepsis is a major clinical problem for which therapeutic interventions have been largely unsuccessful, in spite of promising strategies that were successful in…”
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Roles of histamine, complement and xanthine oxidase in thermal injury of skin by Friedl, HP, Till, GO, Trentz, O, Ward, PA

“…The pathogenesis of burn edema in the skin of rats appears to be related to a role for histamine, xanthine oxidase and oxygen radicals. Histamine and its…”
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Role of C5a in inflammatory responses by Guo, Ren-Feng, Ward, Peter A

“…The complement system not only represents an effective innate immune mechanism of host defense to eradicate microbial pathogens, but it is also widely involved…”
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Immune complex-induced lung and dermal vascular injury. Differing requirements for tumor necrosis factor-alpha and IL-1 by Mulligan, MS, Ward, PA

“…Vascular injury has been induced in rat lung and dermis after deposition of IgG immune complexes (BSA-anti-BSA complexes). By the use of antibodies to…”
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The enigma of sepsis by Riedemann, Niels C, Guo, Ren-Feng, Ward, Peter A

“…Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the disease is not clear. The definition of the clinical manifestations…”
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Evaluation of endotoxin models for the study of sepsis by Remick, Daniel G, Ward, Peter A

“…Many strategies have been proposed for the treatment of sepsis, and most of the proposed treatment modalities have failed in clinical trials. Many of the…”
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Generation of C5a in the absence of C3: a new complement activation pathway by Ward, Peter A, Huber-Lang, Markus, Sarma, J Vidya, Zetoune, Firas S, Rittirsch, Daniel, Neff, Thomas A, McGuire, Stephanie R, Lambris, John D, Warner, Roscoe L, Flierl, Michael A, Hoesel, Laszlo M, Gebhard, Florian, Younger, John G, Drouin, Scott M, Wetsel, Rick A

“…Complement-mediated tissue injury in humans occurs upon deposition of immune complexes, such as in autoimmune diseases and acute respiratory distress syndrome…”
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Novel strategies for the treatment of sepsis by Ward, Peter A, Riedemann, Niels C, Guo, Ren-Feng

“…The history of therapeutic interventions in clinical trials for sepsis has been referred to as the "graveyard for pharmaceutical companies." That is now set to…”
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Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites by Till, G O, Johnson, K J, Kunkel, R, Ward, P A

“…Intravascular activation of the complement system with cobra venom factor results in acute lung injury, which has been quantitated by increases in lung…”
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Rates of stream incision in the middle part of the Arkansas River basin based on late Tertiary to mid-Pleistocene volcanic ash by WARD, P. A, CARTER, B. J

“…Ages and elevations of ash layers correlated with late Tertiary and Pleistocene eruptions in the western US and present stream elevations are used to calculate…”
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Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma by Barker, JN, Jones, ML, Swenson, CL, Sarma, V, Mitra, RS, Ward, PA, Johnson, KJ, Fantone, JC, Dixit, VM, Nickoloff, BJ

“…Monocytes accumulate in the epidermis and along the dermo-epidermal junction in several different inflammatory skin diseases. To determine whether human…”
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Mediators and regulation of neutrophil accumulation in inflammatory responses in lung: insights from the IgG immune complex model by Guo, Ren-Feng, Ward, Peter A

“…Neutrophil trafficking in lung involves transendothelial migration, migration in tissue interstitium, and transepithelial migration. In a rat model of IgG…”
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Percutaneous coronary intervention and adjunctive pharmacotherapy in women: A statement for healthcare professionals from the American Heart Association by LANSKY, Alexandra J, HOCHMAN, Judith S, FERRELL, Margaret, LEON, Martin B, MEHRAN, Roxana, WHITE, Christopher, MIERES, Jennifer H, MOSES, Jeffrey W, STONE, Gregg W, JACOBS, Alice K, WARD, Patricia A, MINTZ, Gary S, FABUNMI, Rosalind, BERGER, Peter B, NEW, Gishel, GRINES, Cindy L, PIETRAS, Cody G, KERN, Morton J

“…More than 1.2 million percutaneous coronary interventions are performed annually in the United States, with only an estimated 33% performed in women, despite…”
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Complement in Ischemia Reperfusion Injury by Riedemann, Niels C., Ward, Peter A.

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Vascular Endothelial-Cadherin Is an Important Determinant of Microvascular Integrity in vivo by Corada, Monica, Mariotti, Massimo, Thurston, Gavin, Smith, Kelly, Kunkel, Robin, Brockhaus, Manfred, Lampugnani, Maria Grazia, Martin-Padura, Ines, Stoppacciaro, Antonella, Ruco, Luigi, McDonald, Donald M., Ward, Peter A., Dejana, Elisabetta

“…In the present paper, we characterize an antibody, mAb BV13, directed to mouse vascular endothelial (VE)-cadherin, a major adhesive protein of interendothelial…”
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Iloprost inhibits neutrophil-induced lung injury and neutrophil adherence to endothelial monolayers by Riva, C M, Morganroth, M L, Ljungman, A G, Schoeneich, S O, Marks, R M, Todd, 3rd, R F, Ward, P A, Boxer, L A

“…We hypothesized that Iloprost, a long-acting prostacyclin analog, would inhibit neutrophil (PMN)-induced lung injury and decrease PMN adherence to vascular…”
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