Search Results - "Ward, Matthew H"

Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway by Boyer, Seth, Lee, Ho-Joon, Steele, Nina, Zhang, Li, Sajjakulnukit, Peter, Andren, Anthony, Ward, Matthew H, Singh, Rima, Basrur, Venkatesha, Zhang, Yaqing, Nesvizhskii, Alexey I, Pasca di Magliano, Marina, Halbrook, Christopher J, Lyssiotis, Costas A

“…The pancreatic ductal adenocarcinoma microenvironment is composed of a variety of cell types and marked by extensive fibrosis and inflammation…”
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Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance by Nwosu, Zeribe Chike, Piorońska, Weronika, Battello, Nadia, Zimmer, Andreas David, Dewidar, Bedair, Han, Mei, Pereira, Sharon, Blagojevic, Biljana, Castven, Darko, Charlestin, Verodia, Holenya, Pavlo, Lochead, Julia, De La Torre, Carolina, Gretz, Norbert, Sajjakulnukit, Peter, Zhang, Li, Ward, Matthew H., Marquardt, Jens U., di Magliano, Marina Pasca, Lyssiotis, Costas A., Sleeman, Jonathan, Wölfl, Stefan, Ebert, Matthias Philip, Meyer, Christoph, Hofmann, Ute, Dooley, Steven

“…The extracellular signal-regulated kinase (ERK) pathway regulates cell growth, and is hyper-activated and associated with drug resistance in hepatocellular…”
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Uridine: as sweet as sugar for some cells? by Ward, Matthew H., Nwosu, Zeribe C., Lyssiotis, Costas A.

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Uridine-derived ribose fuels glucose-restricted pancreatic cancer by Nwosu, Zeribe C., Ward, Matthew H., Sajjakulnukit, Peter, Poudel, Pawan, Ragulan, Chanthirika, Kasperek, Steven, Radyk, Megan, Sutton, Damien, Menjivar, Rosa E., Andren, Anthony, Apiz-Saab, Juan J., Tolstyka, Zachary, Brown, Kristee, Lee, Ho-Joon, Dzierozynski, Lindsey N., He, Xi, PS, Hari, Ugras, Julia, Nyamundanda, Gift, Zhang, Li, Halbrook, Christopher J., Carpenter, Eileen S., Shi, Jiaqi, Shriver, Leah P., Patti, Gary J., Muir, Alexander, Pasca di Magliano, Marina, Sadanandam, Anguraj, Lyssiotis, Costas A.

“…Pancreatic ductal adenocarcinoma (PDA) is a lethal disease notoriously resistant to therapy 1 , 2 . This is mediated in part by a complex tumour…”
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The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes by Higgins, Cassandra B., Adams, Joshua A., Ward, Matthew H., Greenberg, Zev J., Milewska, Małgorzata, Sun, Jiameng, Zhang, Yiming, Chiquetto Paracatu, Luana, Dong, Qian, Ballentine, Samuel, Li, Weikai, Wandzik, Ilona, Schuettpelz, Laura G., DeBosch, Brian J.

“…Tetraspanins are transmembrane signaling and proinflammatory proteins. Prior work demonstrates that the tetraspanin, CD53/TSPAN25/MOX44, mediates B-cell…”
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Agency and Resilience Along the Arizona-Sonora Border: How Unauthorized Migrants Become Aware of and Resist Contemporary U.S. Nativist Mobilization by Martínez, Daniel E., Ward, Matthew H.

“…Little is known about the extra-political consequences of contemporary U.S.-based nativist mobilization as well as the resilience unauthorized migrants display…”
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Abstract C36: A roadmap for targeting cysteine dependency in a subset of pancreatic cancer by Nwosu, Zeribe C., Ward, Matthew H., Sajjakulnukit, Peter, Zhang, Li, Magliano, Marina Pasca di, Lyssiotis, Costas A.

“…Cysteine is a crucial amino acid for glutathione biosynthesis, which is necessary for the maintenance of cellular antioxidant defense. Recent studies have…”
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Abstract C037: Characterization of cysteine dependency implicates glutathione metabolism as a critical adaptation axis in pancreatic cancer by Ezeh, Chiamaka J, Ward, Matthew H, Jain, Chesta, Charlestin, Verodia, Kim, Daeho D, Yang, Andrew, Nassif, Maya, Mbah, Nneka, Sajjakulnukit, Peter, Andren, Anthony, Zhang, Li, Pasca di Magliano, Marina, Lyssiotis, Costas A, Nwosu, Zeribe C

“…Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer that is highly malignant and lethal. The treatment options are limited, contributing to its high…”
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Abstract PR10: Uridine-to-ribose axis supports glucose-restricted pancreatic cancer by Nwosu, Zeribe C., Ward, Matthew H., Sajjakulnukit, Peter, Poudel, Pawan, Ragulan, Chanthirika, Kasperek, Steven, Radyk, Megan, Sutton, Damien, Menjivar, Rosa E., Andren, Anthony, Apiz-Saab, Juan J., Tolstyka, Zachary, Brown, Kristee, Lee, Ho-Joon, Dzierozynski, Lindsey, He, Xi, Ps, Hari, Ugras, Julia, Nyamundanda, Gift, Zhang, Li, Halbrook, Christopher J., Carpenter, Eileen, Shi, Jiaqi, Shriver, Leah P., Patti, Gary J., Muir, Alexander, di Magliano, Marina Pasca, Sadanandam, Anguraj, Lyssiotis, Costas A.

“…Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with a 5-year survival rate of 12% in the USA. PDA highly rely on glucose but is surrounded by a…”
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