Search Results - "Ward, Mark P."
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Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?
Published in Molecular cancer (31-03-2021)“…Cancer cells that transit from primary tumours into the circulatory system are known as circulating tumour cells (CTCs). These cancer cells have unique…”
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Ex vivo expansion of circulating tumour cells (CTCs)
Published in Scientific reports (06-03-2023)“…Circulating tumour cells (CTCs) are a critical intermediate step in the process of cancer metastasis. The reliability of CTC isolation/purification has limited…”
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Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview
Published in International journal of molecular sciences (07-04-2021)“…Gynecological cancers pose an important public health issue, with a high incidence among women of all ages. Gynecological cancers such as malignant germ-cell…”
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An Overview of the Role of Long Non-Coding RNAs in Human Choriocarcinoma
Published in International journal of molecular sciences (17-06-2021)“…Choriocarcinoma (CC), a subtype of trophoblastic disease, is a rare and highly aggressive neoplasm. There are two main CC subtypes: gestational and…”
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LncRNA MORT (ZNF667-AS1) in Cancer—Is There a Possible Role in Gynecological Malignancies?
Published in International journal of molecular sciences (01-08-2021)“…Gynecological cancers (GCs) are currently among the major threats to female health. Moreover, there are different histologic subtypes of these cancers, which…”
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A risk score for prediction of venous thromboembolism in gynecologic cancer: The Thrombogyn score
Published in Research and practice in thrombosis and haemostasis (01-07-2020)“…Gynecologic cancers are associated with high rates of venous thromboembolism (VTE), which is exacerbated by pelvic surgery and chemotherapy. The aim of this…”
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The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon
Published in Translational oncology (01-12-2021)“…•Platelet cancer cell interactions are a key factor in driving the pro-metastatic phenotype.•Platelet cancer cell interactions appear to be mediated by 5 key…”
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Plasminogen activator inhibitor 1 is associated with high-grade serous ovarian cancer metastasis and is reduced in patients who have received neoadjuvant chemotherapy
Published in Frontiers in cell and developmental biology (2023)“…High-grade serous ovarian cancer (HGSOC) is the most prevalent and deadliest subtype of epithelial ovarian cancer (EOC), killing over 140,000 people annually…”
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How CSL Biotech became a global player: getting ahead of the competition
Published in The Journal of business strategy (22-03-2023)“…Purpose This paper aims to examine the role strategic problem identification and resolution played in identifying and capturing new sources of competitive…”
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Potential role of the CD39-CD73 ATP-adenosine pathway in platelet mediated dissemination of circulating tumour cells
Published in British journal of cancer (01-09-2024)Get full text
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Extracellular vesicles in ovarian cancer - A role in venous thromboembolism?
Published in Thrombosis update (01-05-2021)Get full text
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Circulating tumour cells: The Good, the Bad and the Ugly
Published in Biochimica et biophysica acta. Reviews on cancer (01-03-2023)“…This review is an overview of the current knowledge regarding circulating tumour cells (CTCs), which are potentially the most lethal type of cancer cell, and…”
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Unravelling the biological and clinical challenges of circulating tumour cells in epithelial ovarian carcinoma
Published in Cancer letters (28-11-2024)“…Epithelial ovarian carcinoma (EOC) is the eighth most common cancer in women and the leading cause of gynaecological cancer death, predominantly due to the…”
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Procoagulant activity in high grade serous ovarian cancer patients following neoadjuvant chemotherapy-The role of the activated protein C pathway
Published in Thrombosis research (01-04-2021)“…Ovarian cancer patients are at high risk of thrombosis particularly during chemotherapy treatment however the mechanism is not understood. The aim of this…”
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A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Published in Molecular oncology (06-08-2024)“…Circulating tumor cells (CTCs) have potential as diagnostic, prognostic, and predictive biomarkers in solid tumors. Despite Food and Drug Administration (FDA)…”
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(In)Distinctive Role of Long Non-Coding RNAs in Common and Rare Ovarian Cancers
Published in Cancers (09-10-2021)“…Rare ovarian cancers (ROCs) are OCs with an annual incidence of fewer than 6 cases per 100,000 women. They affect women of all ages, but due to their low…”
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Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression
Published in Scientific reports (18-08-2023)“…Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor…”
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Prediction of Prostate Cancer Biochemical and Clinical Recurrence Is Improved by IHC-Assisted Grading Using Appl1, Sortilin and Syndecan-1
Published in Cancers (16-06-2023)“…Gleason scoring is used within a five-tier risk stratification system to guide therapeutic decisions for patients with prostate cancer. This study aimed to…”
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BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer
Published in Oncotarget (20-03-2018)“…Triple-negative breast cancer (TNBC), is a heterogeneous disease characterised by absence of expression of the estrogen receptor (ER), progesterone receptor…”
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Correction: BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer
Published in Oncotarget (03-05-2019)“…[This corrects the article DOI: 10.18632/oncotarget.24590.]…”
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