Search Results - "Ward, Grace"

Convergence at Poverty Point: a revised chronology of the Late Archaic Lower Mississippi Valley by Grooms, Seth B., Ward, Grace M.V., Kidder, Tristram R.

“…The Poverty Point site, located in the Lower Mississippi Valley of the south-eastern United States, is commonly considered a centre of innovation that exported…”
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Cardiac PDGFRα+ interstitial cells generate spontaneous inward currents that contribute to excitability in the heart by Zheng, Haifeng, Peri, Lauren, Ward, Grace K., Sanders, Kenton M., Ward, Sean M.

“…The cell types and conductance that contribute to normal cardiac functions remain under investigation. We used mice that express an enhanced green fluorescent…”
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Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity by Wright, Gabriela, Golubeva, Volha, Remsing Rix, Lily L, Berndt, Norbert, Luo, Yunting, Ward, Grace A, Gray, Jhanelle E, Schonbrunn, Ernst, Lawrence, Harshani R, Monteiro, Alvaro N.A, Rix, Uwe

“…Inhibition of the WEE1 tyrosine kinase enhances anticancer chemotherapy efficacy. Accordingly, the WEE1 inhibitor AZD1775 (previously MK-1775) is currently…”
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Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes by Ward, Grace A, Dalton, 3rd, Robert P, Meyer, Benjamin S, McLemore, Amy F, Aldrich, Amy L, Lam, Nghi B, Onimus, Alexis H, Vincelette, Nicole D, Trinh, Thu Le, Chen, Xianghong, Calescibetta, Alexandra R, Christiansen, Sean M, Hou, Hsin-An, Johnson, Joseph O, Wright, Kenneth L, Padron, Eric, Eksioglu, Erika A, List, Alan F

“…Myelodysplastic Syndromes (MDSs) are bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, including NLRP3 inflammasome…”
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Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes by McLemore, Amy F., Hou, Hsin-An, Meyer, Benjamin S., Lam, Nghi B., Ward, Grace A., Aldrich, Amy L., Rodrigues, Matthew A., Vedder, Alexis, Zhang, Ling, Padron, Eric, Vincelette, Nicole D., Sallman, David A., Abdel-Wahab, Omar, List, Alan F., McGraw, Kathy L.

“…NLRP3 inflammasome and IFN-stimulated gene (ISG) induction are key biological drivers of ineffective hematopoiesis and inflammation in myelodysplastic…”
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Constitutively Activated DAP12 Induces Functional Anti-Tumor Activation and Maturation of Human Monocyte-Derived DC by Dalton, Robert, Calescibetta, Alexandra, Zhou, Jun Min, Maurin, Michelle, Ward, Grace, Trinh, Thu Le, Tu, Nhan, Gilvary, Danielle, Chen, Xianghong, Cheng, Pingyan, Kostenko, Elena, Wei, Sheng, Wright, Kenneth L, Eksioglu, Erika A

“…Dendritic cells (DCs) are professional antigen presenting cells with a great capacity for cross-presentation of exogenous antigens from which robust anti-tumor…”
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Circulating Oxidized mtDNA is Associated Broadly with Cardiovascular Disease in a Longitudinal Cohort Study of Psoriasis by Lateef, Sundus S, Ward, Grace A, Li, Haiou, Pantoja, Carla, Florida, Elizabeth, Hong, Christin G, Rodante, Justin, Keel, Andrew, Chen, Marcus Y, Sorokin, Alexander V, Playford, Martin P, Mehta, Nehal N

“…Psoriasis (PSO) is a chronic and systemic inflammatory autoimmune disease associated with atherosclerosis and myocardial infarction. Given that atherosclerosis…”
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Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes by Ward, Grace A., McGraw, Kathy L., Abbas-Aghababazadeh, Farnoosh, Meyer, Benjamin S., McLemore, Amy F., Vincelette, Nicole D., Lam, Nghi B., Aldrich, Amy L., Al Ali, Najla H., Padron, Eric, Pinilla-Ibarz, Javier, Masala, Erico, Santini, Valeria, Kosmider, Olivier, Fontenay, Michaela, Fenaux, Pierre, Johnson, Joseph, Fridley, Brooke L., List, Alan F.

“…Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem cell malignancies that can phenotypically resemble other hematologic disorders. Thus,…”
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Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study by Basiorka, Ashley A, McGraw, Kathy L, Abbas-Aghababazadeh, Farnoosh, McLemore, Amy F, Vincelette, Nicole D, Ward, Grace A, Eksioglu, Erika A, Sallman, David A, Ali, Najla Al, Padron, Eric, Pinilla-Ibarz, Javier, Komrokji, Rami, Masala, Erico, Santini, Valeria, Kosmider, Olivier, Fontenay, Michaela, Fenaux, Pierre, Sokol, Lubomir, Wei, Sheng, Fridley, Brooke, List, Alan F

“…NLRP3 inflammasome-directed pyroptotic cell death drives ineffective haemopoiesis in myelodysplastic syndromes. During inflammasome assembly, the…”
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Impact of an Aboriginal and Torres Strait Islander brief intervention training program on health staff participants' own health behaviours: Smoking, nutrition and physical activity by Cunningham, Frances C., Murphy, Majella G., Ward, Grace, Fagan, Royden, Arley, Brian, Hornby‐Turner, Yvonne C., d'Abbs, Peter H.

“…Issues addressed: Little research has been conducted on the impact of Aboriginal and Torres Strait Islander brief intervention training programs on health…”
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A novel class of interstitial cells in the mouse and monkey female reproductive tracts by Peri, Lauren E, Koh, Byoung H, Ward, Grace K, Bayguinov, Yulia, Hwang, Sung Jin, Gould, Thomas W, Mullan, Catrina J, Sanders, Kenton M, Ward, Sean M

“…Growing evidence suggests important roles for specialized platelet-derived growth factor receptor alpha-positive (PDGFRalpha(+)) cells in regulating the…”
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1516 Advancing immunotherapy through patient-identified regulators of T cell stemness by Zebley, Caitlin, Kang, Tae Gun, Mi, Tian, Alli, Shanta, Ward, Grace, Vasandan, Anoop Babu, Carson, Shala, Lan, Xin, Jones, Peter, Baylin, Stephen, Groenbæk, Kristen, O’Connell, Casey, Youngblood, Benjamin

“…BackgroundEpigenetic reinforcement of T cell exhaustion is a well-established barrier limiting multiple modalities of T cell-based immunotherapies for cancer…”
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CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies by Trinh, ThuLe, Adams, William A., Calescibetta, Alexandra, Tu, Nhan, Dalton, Robert, So, Tina, Wei, Max, Ward, Grace, Kostenko, Elena, Christiansen, Sean, Cen, Ling, McLemore, Amy, Reed, Kayla, Whitting, Junmin, Gilvary, Danielle, Blanco, Neale Lopez, Segura, Carlos Moran, Nguyen, Jonathan, Kandell, Wendy, Chen, Xianghong, Cheng, Pingyan, Wright, Gabriela M., Cress, W. Douglas, Liu, Jinghong, Wright, Kenneth L., Wei, Sheng, Eksioglu, Erika A.

“…Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells…”
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A Novel Class of Interstitial Cells in the Mouse and Monkey Female Reproductive Tracts1 by Peri, Lauren E, Koh, Byoung H, Ward, Grace K, Bayguinov, Yulia, Hwang, Sung Jin, Gould, Thomas W, Mullan, Catrina J, Sanders, Kenton M, Ward, Sean M

“…Growing evidence suggests important roles for specialized platelet-derived growth factor receptor alpha-positive (PDGFRalpha+) cells in regulating the…”
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Effects of targeted epigenetic modifications on T – cell reprogramming by Norman, Allison R, Ward, Grace Anne, Zebley, Caitlin C, Youngblood, Ben A

“…Abstract Over the last decade there have been huge advances in DNA sequencing technology, allowing cancer patients to undergo genomic diagnosis within days of…”
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Anodal transcranial direct current stimulation over the primary motor cortex attenuates capsaicin‐induced dynamic mechanical allodynia and mechanical pain sensitivity in humans by Hughes, Sam W., Ward, Grace, Strutton, Paul H.

“…Background Anodal transcranial direct current stimulation over the primary cortex has been shown to activate regions of the brain involved in the descending…”
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TLR9-Selective Therapeutic Targeting of MDS Clones with a CpG Payload-Delivery Strategy by Ward, Grace A, Christiansen, Sean, Wright, Gabriela, Wei, Sheng, List, Alan F., Wright, Kenneth, Eksioglu, Erika A

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Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma by Cheng, Pingyan, Chen, Xianghong, Dalton, Robert, Calescibetta, Alexandra, So, Tina, Gilvary, Danielle, Ward, Grace, Smith, Victoria, Eckard, Sterling, Fox, Judith A., Guenot, Jeanmarie, Markowitz, Joseph, Cleveland, John L., Wright, Kenneth L., List, Alan F., Wei, Sheng, Eksioglu, Erika A.

“…We have reported previously that CD33hi myeloid-derived suppressor cells (MDSCs) play a direct role in the pathogenesis of myelodysplastic syndromes (MDSs) and…”
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Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes by Ward, Grace A, McGraw, Kathy, McLemore, Amy F, Lam, Nghi B, Hou, Hsin-An, Meyer, Benjamin S., List, Alan F.

“…Myelodysplastic Syndromes (MDS) are bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, Nlrp3 inflammasome (IFM)…”
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The Historical Ecology of Late Archaic Mound Building in the Lower Mississippi Valley by Ward, Grace Mary Virginia

“…This dissertation is a social and ecological analysis of the history of Native American mound-building from approximately 4000 to 3000 years ago in the Lower…”
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