Search Results - "Ward, G D"

The maternal brain is more flexible and responsive at rest: effective connectivity of the parental caregiving network in postpartum mothers by Orchard, Edwina R., Voigt, Katharina, Chopra, Sidhant, Thapa, Tribikram, Ward, Phillip G. D., Egan, Gary F., Jamadar, Sharna D.

“…The field of neuroscience has largely overlooked the impact of motherhood on brain function outside the context of responses to infant stimuli. Here, we apply…”
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Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth by Noy, P J, Lodhia, P, Khan, K, Zhuang, X, Ward, D G, Verissimo, A R, Bacon, A, Bicknell, R

“…We previously identified CLEC14A as a tumour endothelial marker. Here we show that CLEC14A is a regulator of sprouting angiogenesis in vitro and in vivo …”
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Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection by Baxter, L., Gordon, N. S., Ott, S., Wang, J., Patel, P., Goel, A., Piechocki, K., Silcock, L., Sale, C., Zeegers, M. P., Cheng, K. K., James, N. D., Bryan, R. T., Ward, D. G.

“…Mutations at specific hotspots in non-coding regions of ADGRG6, PLEKHS1, WDR74, TBC1D12 and LEPROTL1 frequently occur in bladder cancer (BC). These mutations…”
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Identification of serum biomarkers for colon cancer by proteomic analysis by WARD, D. G, SUGGETT, N, CHENG, Y, WEI, W, JOHNSON, H, BILLINGHAM, L. J, ISMAIL, T, WAKELAM, M. J. O, JOHNSON, P. J, MARTIN, A

“…Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis. Early detection greatly improves prognosis; however, the invasive,…”
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Urinary EpCAM in urothelial bladder cancer patients: characterisation and evaluation of biomarker potential by Bryan, R T, Shimwell, N J, Wei, W, Devall, A J, Pirrie, S J, James, N D, Zeegers, M P, Cheng, K K, Martin, A, Ward, D G

“…Background: Epithelial cell adhesion molecule is overexpressed in bladder tumours and released from bladder cancer cells in vitro . We test the hypotheses that…”
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Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma by Shimwell, N J, Bryan, R T, Wei, W, James, N D, Cheng, K K, Zeegers, M P, Johnson, P J, Martin, A, Ward, D G

“…Background: Proteomic discovery of cancer biomarkers in body fluids is challenging because of their low abundance in a complex background. Altered gene…”
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Relationship between parenthood and cortical thickness in late adulthood by Orchard, Edwina R, Ward, Phillip G D, Sforazzini, Francesco, Storey, Elsdon, Egan, Gary F, Jamadar, Sharna D

“…Pregnancy and the early postpartum period alter the structure of the brain; particularly in regions related to parental care. However, the enduring effects of…”
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Longitudinal evaluation of iron concentration and atrophy in the dentate nuclei in friedreich ataxia by Ward, Phillip G. D., Harding, Ian H., Close, Thomas G., Corben, Louise A., Delatycki, Martin B., Storey, Elsdon, Georgiou‐Karistianis, Nellie, Egan, Gary F.

“…Background Friedreich ataxia is a recessively inherited, progressive neurological disease characterized by impaired mitochondrial iron metabolism. The dentate…”
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Estimation of simultaneous BOLD and dynamic FDG metabolic brain activations using a multimodality concatenated ICA (mcICA) method by Li, Shenpeng, Jamadar, Sharna D, Ward, Phillip G D, Egan, Gary F, Chen, Zhaolin

“…Simultaneous magnetic resonance and positron emission tomography provides an opportunity to measure brain haemodynamics and metabolism in a single scan…”
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Task-evoked simultaneous FDG-PET and fMRI data for measurement of neural metabolism in the human visual cortex by Jamadar, Sharna D., Zhong, Shenjun, Carey, Alexandra, McIntyre, Richard, Ward, Phillip G. D., Fornito, Alex, Premaratne, Malin, Jon Shah, N, O’Brien, Kieran, Stäb, Daniel, Chen, Zhaolin, Egan, Gary F.

“…Understanding how the living human brain functions requires sophisticated in vivo neuroimaging technologies to characterise the complexity of neuroanatomy,…”
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Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in hepatocellular carcinoma by Teng, M, Pirrie, S, Ward, D G, Assi, L K, Hughes, R G, Stocken, D, Johnson, P J

“…Background: Mass spectroscopy analysis suggested low serum albumin and high immunoglobulin free light chain (sFLC) levels may have diagnostic value in…”
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Identification of macrophage migration inhibitory factor and human neutrophil peptides 1-3 as potential biomarkers for gastric cancer by Mohri, Y, Mohri, T, Wei, W, Qi, Y-J, Martin, A, Miki, C, Kusunoki, M, Ward, D G, Johnson, P J

“…Background: Proteomic methods have the potential to meet the urgent need for better cancer biomarkers. We have used a range of proteomic analyses of serum and…”
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Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis by WARD, D. G, CHENG, Y, N'KONTCHOU, G, THAR, T. T, BARGET, N, WEI, W, BILLINGHAM, L. J, MARTIN, A, BEAUGRAND, M, JOHNSON, P. J

“…Early diagnosis of hepatocellular carcinoma (HCC) is the key to the delivery of effective therapies. The conventional serological diagnostic test, estimation…”
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Macrophage migration inhibitory factor and DJ-1 in gastric cancer: differences between high-incidence and low-incidence areas by Shimwell, N J, Ward, D G, Mohri, Y, Mohri, T, Pallan, L, Teng, M, Miki, Y C, Kusunoki, M, Tucker, O, Wei, W, Morse, J, Johnson, P J

“…Background: There is a need for sensitive and specific blood-borne markers for the detection of gastric cancer. Raised serum macrophage inhibitory factor (MIF)…”
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Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function by Wrigglesworth, Jo, Ryan, Joanne, Ward, Phillip G D, Woods, Robyn L, Storey, Elsdon, Egan, Gary F, Murray, Anne, Espinoza, Sara E, Shah, Raj C, Trevaks, Ruth E, Ward, Stephanie A, Harding, Ian H

“…Neuroimaging-based 'brain age' can identify individuals with 'advanced' or 'resilient' brain aging. Brain-predicted age difference (brain-PAD) is predictive of…”
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Timescales of spontaneous fMRI fluctuations relate to structural connectivity in the brain by Fallon, John, Ward, Phillip G. D., Parkes, Linden, Oldham, Stuart, Arnatkevičiūtė, Aurina, Fornito, Alex, Fulcher, Ben D.

“…Intrinsic timescales of activity fluctuations vary hierarchically across the brain. This variation reflects a broad gradient of functional specialization in…”
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Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain by Jamadar, Sharna D., Ward, Phillip G. D., Close, Thomas G., Fornito, Alex, Premaratne, Malin, O’Brien, Kieran, Stäb, Daniel, Chen, Zhaolin, Shah, N. Jon, Egan, Gary F.

“…Simultaneous [18 F]-fluorodeoxyglucose positron emission tomography and functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image…”
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Analysis of continuous infusion functional PET (fPET) in the human brain by Li, Shenpeng, Jamadar, Sharna D., Ward, Phillip G.D., Premaratne, Malin, Egan, Gary F., Chen, Zhaolin

“…Functional positron emission tomography (fPET) is a neuroimaging method involving continuous infusion of 18-F-fluorodeoxyglucose (FDG) radiotracer during the…”
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Preclinical and post-treatment changes in the HCC-associated serum proteome by WARD, D. G, CHENG, Y, N'KONTCHOU, G, THAR, T. T, BARGET, N, WEI, W, MARTIN, A, BEAUGRAND, M, JOHNSON, P. J

“…SELDI-based proteomic profiling of body fluids is currently in widespread use for cancer biomarker discovery. We have successfully used this technology for the…”
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Combining images and anatomical knowledge to improve automated vein segmentation in MRI by Ward, Phillip G.D., Ferris, Nicholas J., Raniga, Parnesh, Dowe, David L., Ng, Amanda C.L., Barnes, David G., Egan, Gary F.

“…To improve the accuracy of automated vein segmentation by combining susceptibility-weighted images (SWI), quantitative susceptibility maps (QSM), and a vein…”
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