Search Results - "Ward, F. J."

The complexity of DNA damage: relevance to biological consequences by Ward, J F

“…Ionizing radiation causes both singly and multiply damaged sites in DNA when the range of radical migration is limited by the presence of hydroxyl radical…”
Get more information

Radiation Mutagenesis: The Initial DNA Lesions Responsible by Ward, J. F.

“…This paper is an attempt to initiate a discussion about the causes of radiation-induced mutagenesis. It considers the evidence for the involvement of singly…”
Get full text

Integrating chemohormonal therapy and surgery in known or suspected lymph node metastatic prostate cancer by Zurita, A J, Pisters, L L, Wang, X, Troncoso, P, Dieringer, P, Ward, J F, Davis, J W, Pettaway, C A, Logothetis, C J, Pagliaro, L C

“…Background: Prostate cancer persisting in the primary site after systemic therapy may contribute to emergence of resistance and progression. We previously…”
Get full text

DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability by Ward, J F

Get more information

Immediate and postoperative complications of transurethral prostatectomy in the 1990s by Borboroglu, P G, Kane, C J, Ward, J F, Roberts, J L, Sands, J P

“…We compare the morbidity, mortality, hospitalization and urethral catheter time of contemporary transurethral prostatectomy to historical series, and evaluate…”
Get more information

Repair of oxidative DNA damage by amino acids by Milligan, J. R., Aguilera, J. A., Ly, A., Tran, N. Q., Hoang, O., Ward, J. F.

“…Guanyl radicals, the product of the removal of a single electron from guanine, are produced in DNA by the direct effect of ionizing radiation. We have produced…”
Get full text

Complexity of damage produced by ionizing radiation by Ward, J F

Get full text

DNA strand-break yields after post-irradiation incubation with base excision repair endonucleases implicate hydroxyl radical pairs in double-strand break formation by MILLIGAN, J. R, AGUILERA, J. A, NGUYEN, T.-T. D, PAGLINAWAN, R. A, WARD, J. F

“…Purpose : To determine the increases in SSB and DSB yields after post gamma-irradiation incubation of plasmid DNA with the Escherichia coli base excision…”
Get full text

Mucosal tolerance and suppression of collagen‐induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184‐198 of bovine type II collagen (CII) expressing a dominant T cell epitope by STAINES, N. A., HARPER, N., WARD, F. J., MALMSTRÖM, V., HOLMDAHL, R., BANSAL, S.

“…SUMMARY The purpose of the study was to map the dominant T cell epitope of the CB11 sequence of CII in RT1u haplotype rats and to determine if, when used as a…”
Get full text

Relationship between obesity and race in predicting adverse pathologic variables in patients undergoing radical prostatectomy by Amling, Christopher L., Kane, Christopher J., Riffenburgh, Robert H., Ward, John F., Roberts, James L., Lance, Raymond S., Friedrichs, Paul A., Moul, Judd W.

“…Objectives. To determine whether obesity is associated with more advanced prostate cancer (PCa) in radical prostatectomy patients and to explore the ethnic…”
Get full text

Focal laser ablation as clinical treatment of prostate cancer: report from a Delphi consensus project by van Luijtelaar, A., Greenwood, B. M., Ahmed, H. U., Barqawi, A. B., Barret, E., Bomers, J. G. R., Brausi, M. A., Choyke, P. L., Cooperberg, M. R., Eggener, S., Feller, J. F., Frauscher, F., George, A. K., Hindley, R. G., Jenniskens, S. F. M., Klotz, L., Kovacs, G., Lindner, U., Loeb, S., Margolis, D. J., Marks, L. S., May, S., Mcclure, T. D., Montironi, R., Nour, S. G., Oto, A., Polascik, T. J., Rastinehad, A. R., De Reyke, T. M., Reijnen, J. S., de la Rosette, J. J. M. C. H., Sedelaar, J. P. M., Sperling, D. S., Walser, E. M., Ward, J. F., Villers, A., Ghai, S., Fütterer, J. J.

“…Purpose To define the role of focal laser ablation (FLA) as clinical treatment of prostate cancer (PCa) using the Delphi consensus method. Methods A panel of…”
Get full text

Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: a role for ribosomal P protein P0 as an endothelial cell autoantigen by Frampton, G., Moriya, S., Pearson, J. D., Isenberg, D. A., Ward, F. J., Smith, T. A., Panayiotou, A., Staines, N. A., Murphy, J. J.

“…Objective. To attempt to characterize the diversity and nature of antigens recognized by anti‐endothelial cell antibodies (AECA) in patients with systemic…”
Get full text

DNA Damage as the Cause of Ionizing Radiation-Induced Gene Activation by Ward, J. F.

“…Tyrosine kinases have been shown to be activated by both UVA and UVC light and γ irradiation. For UV exposure, a non-DNA target has been proposed. Here the…”
Get full text

Critical Target and Dose and Dose-Rate Responses for the Induction of Chromosomal Instability by Ionizing Radiation by Limoli, Charles L., Corcoran, James J., Milligan, Jamie R., Ward, John F., Morgan, William F.

“…To investigate the critical target, dose response and dose-rate response for the induction of chromosomal instability by ionizing radiation, bromodeoxyuridine…”
Get full text

Variation of Single-Strand Break Yield with Scavenger Concentration for Plasmid DNA Irradiated in Aqueous Solution by Milligan, J. R., Aguilera, J. A., Ward, J. F.

“…We have measured the yield of single-strand breaks (SSBs), induced by 137 Cs γ radiation as assayed by agarose gel electrophoresis, for three plasmids and SV40…”
Get full text

Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization by Eggleton, P., Ward, F. J., Johnson, S., Khamashta, M. A., Hughes, G. R. V., Hajela, V. A., Michalak, M., Corbett, E. F., Staines, N. A., Reid, K. B. M.

“…Extracellular calreticulin (CRT) as well as anti‐CRT antibodies have been reported in patients with various autoimmune disorders and CRT has been implicated in…”
Get full text

DNA strand break yields after post-high LET irradiation incubation with endonuclease-III and evidence for hydroxyl radical clustering by Milligan, J.R., Aguilera, J. A., Paglinawan, R. A., Ward, J. F., Limoli, C. L.

“…Purpose : To determine the increase in single- (SSB) and double-strand break (DSB) yields after post-high LET irradiation incubation of plasmid DNA with the…”
Get full text

A New Method for Introducing Double-Strand Breaks into Cellular DNA by Limoli, C. L., Ward, J. F.

“…A novel method is used to introduce double-strand breaks into cellular DNA containing controlled levels of 5-bromo-2′-deoxyuridine (BrdU). Chinese hamster V79…”
Get full text

Responses of foraging hedgehogs to badger odour by WARD, J.F, MACDONALD, D.W, DONCASTER, C.P

“…Enclosure and field trials were used to investigate the responses of hedgehogs,Erinaceus europaeus, to predator (badger,Meles meles) and non-predator odours…”
Get full text

Yield of DNA Strand Breaks after Base Oxidation of Plasmid DNA by Milligan, J. R., Aguilera, J. A., T-T. D. Nguyen, Ward, J. F., Know, Y. W., He, B., Cunningham, R. P.

“…We have irradiated aerobic aqueous solutions of plasmid DNA with 137 Cs γ rays in the presence of inorganic radical scavengers including nitrite, iodide,…”
Get full text