Search Results - "Ward, Alexandra"

Electronic nicotine delivery system design and aerosol toxicants: A systematic review by Ward, Alexandra M, Yaman, Rola, Ebbert, Jon O

“…Background Electronic nicotine delivery systems (ENDS; e-cigarettes), consisting of a battery, heating element and e-liquid, have evolved significantly with…”
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An evaluation of variation in published estimates of schizophrenia prevalence from 1990─2013: a systematic literature review by Simeone, Jason C, Ward, Alexandra J, Rotella, Philip, Collins, Jenna, Windisch, Ricarda

“…There is a lack of consistency in findings across studies on the prevalence of schizophrenia, and no recent systematic review of the literature exists. The…”
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Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation by Zhou, Ge, Wang, Jiping, Zhao, Mei, Xie, Tong-Xin, Tanaka, Noriaki, Sano, Daisuke, Patel, Ameeta A., Ward, Alexandra M., Sandulache, Vlad C., Jasser, Samar A., Skinner, Heath D., Fitzgerald, Alison Lea, Osman, Abdullah A., Wei, Yongkun, Xia, Xuefeng, Songyang, Zhou, Mills, Gordon B., Hung, Mien-Chie, Caulin, Carlos, Liang, Jiyong, Myers, Jeffrey N.

“…Many mutant p53 proteins (mutp53s) exert oncogenic gain-of-function (GOF) properties, but the mechanisms mediating these functions remain poorly defined. We…”
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Vaporized D-limonene selectively mitigates the acute anxiogenic effects of Δ9-tetrahydrocannabinol in healthy adults who intermittently use cannabis by Spindle, Tory R., Zamarripa, C. Austin, Russo, Ethan, Pollak, Lauren, Bigelow, George, Ward, Alexandra M., Tompson, Bridget, Sempio, Cristina, Shokati, Touraj, Klawitter, Jost, Christians, Uwe, Vandrey, Ryan

“…Cannabis contains hundreds of chemical constituents beyond delta-9-tetrahydrocannabinol (THC), which is believed to drive most of its acute pharmacodynamic…”
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Coupling of V˙E and V˙CO2 kinetics: insights from multiple exercise transitions below the estimated lactate threshold by Ward, Alexandra M. M., Guluzade, Nasimi A., Kowalchuk, John M., Keir, Daniel A.

“…During a step-change in exercise power output (PO), ventilation ( V ˙ E ) increases with a similar time course to the rate of carbon dioxide delivery to the…”
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Size at Birth and Autonomic Function During Psychological Stress by Jones, Alexander, Beda, Alessandro, Ward, Alexandra M.V, Osmond, Clive, Phillips, David I.W, Moore, Vivienne M, Simpson, David M

“…Small size at birth is associated with exaggerated blood pressure responses to psychological stressors, which increase the risk of developing sustained…”
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Commercial Cannabidiol Caution: A New Gold Rush by Scharf, Eugene L., Ward, Alexandra M., Ebbert, Jon O.

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Bioplastics in the General Chemistry Laboratory: Building a Semester-Long Research Experience by Ward, Alexandra M, Wyllie, Graeme R. A

“…We report here a second semester general chemistry laboratory project themed around chitosan-alginate bioplastics. With increasing awareness of plastic…”
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Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients by Osman, Abdullah A, Neskey, David M, Katsonis, Panagiotis, Patel, Ameeta A, Ward, Alexandra M, Hsu, Teng-Kuei, Hicks, Stephanie C, McDonald, Thomas O, Ow, Thomas J, Alves, Marcus Ortega, Pickering, Curtis R, Skinner, Heath D, Zhao, Mei, Sturgis, Eric M, Kies, Merrill S, El-Naggar, Adel, Perrone, Federica, Licitra, Lisa, Bossi, Paolo, Kimmel, Marek, Frederick, Mitchell J, Lichtarge, Olivier, Myers, Jeffrey N

“…TP53 is the most frequently altered gene in head and neck squamous cell carcinoma (HNSCC), with mutations occurring in over two thirds of cases; however, the…”
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Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers by PICKERING, Curtis R, JIEXIN ZHANG, DRUMMOND, Jennifer, EL-NAGGAR, Adel K, GIBBS, Richard, WEINSTEIN, John N, WHEELER, David A, JING WANG, FREDERICK, Mitchell J, MYERS, Jeffrey N, NESKEY, David M, MEI ZHAO, JASSER, Samar A, JIPING WANG, WARD, Alexandra, TSAI, C. Jillian, ALVES, Marcus V. Ortega, ZHOU, Jane H

“…Epidemiologic studies have identified an increasing incidence of squamous cell carcinoma of the oral tongue (SCCOT) in younger patients. DNA isolated from…”
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The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast by Gresham, David, Desai, Michael M, Tucker, Cheryl M, Jenq, Harry T, Pai, Dave A, Ward, Alexandra, DeSevo, Christopher G, Botstein, David, Dunham, Maitreya J

“…The experimental evolution of laboratory populations of microbes provides an opportunity to observe the evolutionary dynamics of adaptation in real time. Until…”
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Energy Drink–Induced Near-Fatal Ventricular Arrhythmia Prevented by an Intracardiac Defibrillator Decades After Operative “Repair” of Tetralogy of Fallot by Ward, Alexandra E., MD, Lipshultz, Steven E., MD, Fisher, Stacy D., MD

“…We describe a 45-year old man who experienced a potentially fatal arrhythmia after consumption of multiple energy drinks. At 5 years old, he underwent “repair”…”
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Carbonyl Compounds in Mainstream Smoke of Hemp Cigarettes by Ward, Alexandra M, Ebbert, Jon O

“…CBD is a major phytocannabinoid in hemp ( containing less than 0.3% THC). Hemp cigarettes are a combustible form of hemp consisting of dried and smokable…”
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Identification and Characterization of Cannabichromene's Major Metabolite Following Incubation with Human Liver Microsomes by Ward, Alexandra M, Shokati, Touraj, Klawitter, Jost, Klawitter, Jelena, Nguyen, Vu, Kozell, Laura, Abbas, Atheir I, Jones, David, Christians, Uwe

“…Cannabichromene (CBC) is a minor cannabinoid within the array of over 120 cannabinoids identified in the plant. While CBC does not comprise a significant…”
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Fetal Programming of the Hypothalamic-Pituitary-Adrenal (HPA) Axis: Low Birth Weight and Central HPA Regulation by Ward, Alexandra M. V., Syddall, Holly E., Wood, Peter J., Chrousos, George P., Phillips, David I. W.

“…Fetal programming of the hypothalamic-pituitary-adrenal (HPA) axis has been proposed as an intermediary in the association between reduced fetal growth and…”
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Delays in treatment intensification with oral antidiabetic drugs and risk of microvascular and macrovascular events in patients with poor glycaemic control: An individual patient simulation study by Folse, Henry J., Mukherjee, Jayanti, Sheehan, John J., Ward, Alexandra J., Pelkey, Ryan L., Dinh, Tuan A., Qin, Lei, Kim, Jennifer

“…Aims To use the Archimedes model to estimate the consequences of delays in oral antidiabetic drug (OAD) treatment intensification on glycaemic control and…”
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Cost-Effectiveness Analysis of Smoking Cessation Interventions in Japan Using a Discrete-Event Simulation by Igarashi, Ataru, Goto, Rei, Suwa, Kiyomi, Yoshikawa, Reiko, Ward, Alexandra J., Moller, Jörgen

“…Background Smoking cessation medications have been shown to yield higher success rates and sustained abstinence than unassisted quit attempts. In Japan, the…”
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Developing a Preoperative Algorithm for the Diagnosis of Uterine Leiomyosarcoma by Lawlor, Hannah, Ward, Alexandra, Maclean, Alison, Lane, Steven, Adishesh, Meera, Taylor, Sian, DeCruze, Shandya Bridget, Hapangama, Dharani Kosala

“…Early diagnosis of the rare and life-threatening uterine leiomyosarcoma (LMS) is essential for prompt treatment, to improve survival. Preoperative distinction…”
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Lifetime Costs of Complications Resulting From Type 2 Diabetes in the U.S by CARO, J. Jaime, WARD, Alexandra J, O'BRIEN, Judith A

“…Lifetime Costs of Complications Resulting From Type 2 Diabetes in the U.S. J. Jaime Caro , MDCM , Alexandra J. Ward , PHD and Judith A. O’Brien , RN From the…”
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Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes by Gresham, David, Curry, Bo, Ward, Alexandra, Gordon, D. Benjamin, Brizuela, Leonardo, Kruglyak, Leonid, Botstein, David

“…The use of DNA microarrays to identify nucleotide variation is almost 20 years old. A variety of improvements in probe design and experimental conditions have…”
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