Search Results - "Waqar Khalid Saeed"

The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury by Yeon Ji Chae, Dae Won Jun, Jai Sun Lee, Waqar Khalid Saeed, Hyeon Tae Kang, Kiseok Jang, Jin Ho Lee

“…Background/Aims: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate…”
Get full text

The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury by Yeon Ji Chae, Dae Won Jun, Jai Sun Lee, Waqar Khalid Saeed, Hyeon Tae Kang, Kiseok Jang, Jin Ho Lee

“…Background/Aims: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate…”
Get full text

The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury by Yeon Ji Chae, Dae Won Jun, Jai Sun Lee, Waqar Khalid Saeed, Hyeon Tae Kang, Kiseok Jang, Jin Ho Lee

“…Background/Aims: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate…”
Get full text

The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury by Yeon Ji Chae, Dae Won Jun, Jai Sun Lee, Waqar Khalid Saeed, Hyeon Tae Kang, Kiseok Jang, Jin Ho Lee

“…Background/Aims: For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate…”
Get full text

Hepatic stellate cells activate and avoid death under necroptosis stimuli: Hepatic fibrosis during necroptosis by Oh, Ju Hee, Saeed, Waqar Khalid, Kim, Hye Young, Lee, Seung Min, Lee, A Hyeon, Park, Gye Ryeol, Yoon, Eileen L, Jun, Dae Won

“…Necroptosis is an emerging cell death pathway that allows cells to undergo "cellular suicide" in a caspase-independent manner. We investigated the fate of…”
Get full text

Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis by Hyo Young Lee, Dae Won Jun, Hyun Jung Kim, Hyunwoo Oh, Waqar Khalid Saeed, Hyeongsik Ahn, Ramsey C. Cheung, Mindie H. Nguyen

“…Background/Aims: A number of clinical trials reported varying effects of cho-lesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We,…”
Get full text

Necroptosis:An emerging type of cell death in liver diseases by Saeed, Waqar Khalid, Jun, Dae Won

“…Cell death has been extensively evaluated for decades and it is well recognized that pharmacological interventions directed to inhibit cell death can prevent…”
Get full text

The global emergence of Chikungunya infection: An integrated view by Manzoor, Khanzadi Nazneen, Javed, Farakh, Ejaz, Muhammad, Ali, Mubashar, Mujaddadi, Neelam, Khan, Abid Ali, Khattak, Aamer Ali, Zaib, Assad, Ahmad, Ibrar, Saeed, Waqar Khalid, Manzoor, Sobia

“…Summary Chikungunya virus (CHIKV) is one of the emerging viruses around the globe. It belongs to the family Togaviridae and genus Alphavirus and is an…”
Get full text

Macro‐encapsulation of mesenchymal stem cells in acute and chronic liver injury animal models by Kang, Hyeon Tae, Jang, Kiseok, Jun, Dae Won, Yoon, Eileen L, Lee, Seung Min, Saeed, Waqar Khalid, Lee, Jin Ho

“…Background and Aim Stem cell treatments using scaffolds for liver disease have been well studied. However, macro‐encapsulation of mesenchymal stem cells (MSCs)…”
Get full text

Ticagrelor, but Not Clopidogrel, Attenuates Hepatic Steatosis in a Model of Metabolic Dysfunction-Associated Steatotic Liver Disease by Lee, Eun Jeoung, Lee, Seung Min, Oh, Ju Hee, Kim, Hye Young, Saeed, Waqar Khalid, Kim, Hyun Sung, Jun, Dae Won

“…Previous studies have suggested that platelets are associated with inflammation and steatosis and may play an important role in liver health. Therefore, we…”
Get full text

Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model by Shim, Sung Gon, Jun, Dae Won, Kim, Eun Kyung, Saeed, Waqar Khalid, Lee, Kang Nyeong, Lee, Hang Lak, Lee, Oh Young, Choi, Ho Soon, Yoon, Byung Chul

“…Background and Aim Several epidemiological studies have shown that coffee intake attenuates the progression of liver fibrosis; however, the mechanism is…”
Get full text

Effect of Stem Cell Treatment on Acute Liver Failure Model Using Scaffold by Kang, Hyeon Tae, Jun, Dae Won, Jang, Kiseok, Hoh, Jeong-Kyu, Lee, Jai Sun, Saeed, Waqar Khalid, Chae, Yeon Ji, Lee, Jin Ho

“…Background Injecting MSCs via blood vessel is most commonly used method, which has a major drawback of safety. The aim of our study was to evaluate efficacy…”
Get full text

Histologic and Metabolic Derangement in High-Fat, High-Fructose, and Combination Diet Animal Models by Nam, Ho Hyun, Jeon, Hye Joon, Kim, Eun Kyung, Jun, Dae Won, Lee, Jai Sun, Saeed, Waqar Khalid

“…Background. We used high-fat (HF), high-fructose (HFr), and combination diets to create a dietary animal model of nonalcoholic fatty liver disease (NAFLD)…”
Get full text

Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis by Lee, Hyo Young, Jun, Dae Won, Kim, Hyun Jung, Oh, Hyunwoo, Saeed, Waqar Khalid, Ahn, Hyeongsik, Cheung, Ramsey C, Nguyen, Mindie H

“…A number of clinical trials reported varying effects of cholesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore,…”
Get full text

Feasibility and Stability of Liver Biopsy before Treatment for Preclinical Nonalcoholic Fatty Liver Studies by Chae, Yeon Ji, Jun, Dae Won, Saeed, Waqar Khalid, Kang, Hyeon Tae, Oh, Ju Hee, Lee, Seung Min, Jang, Kiseok

“…The heterogeneity of histological findings in preclinical diet-induced nonalcoholic fatty liver disease (NAFLD) animal models is highly challenging. Here, we…”
Get full text

The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury by Chae, Yeon Ji, Jun, Dae Won, Lee, Jai Sun, Saeed, Waqar Khalid, Kang, Hyeon Tae, Jang, Kiseok, Lee, Jin Ho

“…For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate. The purpose of this…”
Get full text

Osthol attenuates hepatic steatosis via decreased triglyceride synthesis not by insulin resistance by Nam, Ho Hyun, Jun, Dae Won, Jeon, Hye Joon, Lee, Jai Sun, Saeed, Waqar Khalid, Kim, Eun Kyung

“…AIM: To evaluate the effects of osthol on intrahepatic fat synthesis, β-oxidation, inflammation, and insulin resistance by multifaceted analysis.METHODS:…”
Get full text

Necroptosis signaling in liver diseases: An update by Saeed, Waqar Khalid, Jun, Dae Won, Jang, Kiseok, Koh, Dong Hee

“…[Display omitted] •Role of RIPK3 and MLKL in NAFLD was diverse according to disease model and condition.•RIPK3 ablation seems to convincingly protect from…”
Get full text

Decrease in fat de novo synthesis and chemokine ligand expression in non‐alcoholic fatty liver disease caused by inhibition of mixed lineage kinase domain‐like pseudokinase by Saeed, Waqar Khalid, Jun, Dae Won, Jang, Kiseok, Oh, Ju Hee, Chae, Yeon Ji, Lee, Jai Sun, Koh, Dong Hee, Kang, Hyeon Tae

“…Background and Aim Receptor‐interacting serine/threonine kinase 3 and mixed lineage kinase domain‐like pseudokinase (MLKL) have gained attention as apoptosis…”
Get full text

Deletion of Mixed Lineage Kinase Domain Like Pseudokinase Aggravates Chronic Alcohol-Induced Liver Injury via Increasing Apoptosis by Im, Keon Hwi, Saeed, Waqar Khalid, Kim, Eun Bin, Lee, A. Hyeon, Kim, Ji Eun, Lee, Seung Min, hanning, Xuanyuan, Kim, Hyun Sung, Jun, Dae Won, Yoon, Eileen L.

“…Background and Aim he mixed lineage kinase domain like pseudokinase (MLKL) is known to play a protective role in non-alcoholic fatty liver disease (NAFLD) via…”
Get full text