Search Results - "Wapner, Ronald"

Whole-exome sequencing in the evaluation of fetal structural anomalies: a prospective cohort study by Petrovski, Slavé, Aggarwal, Vimla, Giordano, Jessica L, Stosic, Melissa, Wou, Karen, Bier, Louise, Spiegel, Erica, Brennan, Kelly, Stong, Nicholas, Jobanputra, Vaidehi, Ren, Zhong, Zhu, Xiaolin, Mebane, Caroline, Nahum, Odelia, Wang, Quanli, Kamalakaran, Sitharthan, Malone, Colin, Anyane-Yeboa, Kwame, Miller, Russell, Levy, Brynn, Goldstein, David B, Wapner, Ronald J

“…Identification of chromosomal aneuploidies and copy number variants that are associated with fetal structural anomalies has substantial value. Although…”
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Expanding the scope of noninvasive prenatal testing: detection of fetal microdeletion syndromes by Wapner, Ronald J., MD, Babiarz, Joshua E., PhD, Levy, Brynn, MSc (Med), PhD, Stosic, Melissa, MS, Zimmermann, Bernhard, PhD, Sigurjonsson, Styrmir, PhD, Wayham, Nicholas, BS, Ryan, Allison, PhD, Banjevic, Milena, PhD, Lacroute, Phil, PhD, Hu, Jing, PhD, Hall, Megan P., PhD, Demko, Zachary, PhD, Siddiqui, Asim, PhD, Rabinowitz, Matthew, PhD, Gross, Susan J., MD, Hill, Matthew, PhD, Benn, Peter, DSc

“…Objective The purpose of this study was to estimate the performance of a single-nucleotide polymorphism (SNP)–based noninvasive prenatal test for 5…”
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Confined placental mosaicism and its impact on confirmation of NIPT results by Mardy, Anne, Wapner, Ronald J.

“…Non‐invasive prenatal testing (NIPT) has been widely used to screen for common aneuploidies since 2011. While NIPT is highly sensitive and specific, false…”
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Cell-free DNA Analysis for Noninvasive Examination of Trisomy by Norton, Mary E, Jacobsson, Bo, Swamy, Geeta K, Laurent, Louise C, Ranzini, Angela C, Brar, Herb, Tomlinson, Mark W, Pereira, Leonardo, Spitz, Jean L, Hollemon, Desiree, Cuckle, Howard, Musci, Thomas J, Wapner, Ronald J

“…This multicenter study compared a prenatal assay of cell-free DNA with a standard method of screening for trisomies among women at average risk. The positive…”
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Noninvasive prenatal screening or advanced diagnostic testing: caveat emptor by Evans, Mark I., MD, Wapner, Ronald J., MD, Berkowitz, Richard L., MD

“…The past few years have seen extraordinary advances in prenatal genetic practice led by 2 major technological advances; next-generation sequencing of cell-free…”
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The mechanical role of the cervix in pregnancy by Myers, Kristin M, Feltovich, Helen, Mazza, Edoardo, Vink, Joy, Bajka, Michael, Wapner, Ronald J, Hall, Timothy J, House, Michael

“…Abstract Appropriate mechanical function of the uterine cervix is critical for maintaining a pregnancy to term so that the fetus can develop fully. At the end…”
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Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women by Yao, Wang, Gan, Yu, Myers, Kristin M, Vink, Joy Y, Wapner, Ronald J, Hendon, Christine P

“…The structural integrity of the cervix in pregnancy is necessary for carrying a pregnancy until term, and the organization of human cervical tissue collagen…”
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Genetic testing for unexplained perinatal disorders by Hays, Thomas, Wapner, Ronald J.

“…Perinatal disorders include stillbirth, congenital structural anomalies, and critical illnesses in neonates. The cause of these is often unknown despite a…”
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Promises, pitfalls and practicalities of prenatal whole exome sequencing by Best, Sunayna, Wou, Karen, Vora, Neeta, Van der Veyver, Ignatia B., Wapner, Ronald, Chitty, Lyn S.

“…Prenatal genetic diagnosis provides information for pregnancy and perinatal decision‐making and management. In several small series, prenatal whole exome…”
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Modeled Fetal Risk of Genetic Diseases Identified by Expanded Carrier Screening by Haque, Imran S, Lazarin, Gabriel A, Kang, H. Peter, Evans, Eric A, Goldberg, James D, Wapner, Ronald J

“…IMPORTANCE: Screening for carrier status of a limited number of single-gene conditions is the current standard of prenatal care. Methods have become available…”
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Association of Copy Number Variants With Specific Ultrasonographically Detected Fetal Anomalies by Donnelly, Jennifer C., Platt, Lawrence D., Rebarber, Andrei, Zachary, Julia, Grobman, William A., Wapner, Ronald J.

“…OBJECTIVE:To evaluate the association of other-than-common benign copy number variants with specific fetal abnormalities detected by ultrasonogram…”
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Chromosomal Microarray versus Karyotyping for Prenatal Diagnosis by Wapner, Ronald J, Martin, Christa Lese, Levy, Brynn, Ballif, Blake C, Eng, Christine M, Zachary, Julia M, Savage, Melissa, Platt, Lawrence D, Saltzman, Daniel, Grobman, William A, Klugman, Susan, Scholl, Thomas, Simpson, Joe Leigh, McCall, Kimberly, Aggarwal, Vimla S, Bunke, Brian, Nahum, Odelia, Patel, Ankita, Lamb, Allen N, Thom, Elizabeth A, Beaudet, Arthur L, Ledbetter, David H, Shaffer, Lisa G, Jackson, Laird

“…This large, systematic study of prenatal diagnosis shows that chromosomal microarray analysis provided additional, clinically significant cytogenetic…”
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Genomics of stillbirth by Giordano, Jessica L., Wapner, Ronald J.

“…Stillbirth, defined as fetal death at 20 weeks gestation or later, is a devastating pregnancy outcome affecting 1 in 175 pregnancies in the United States…”
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Racial Disparities in Adverse Pregnancy Outcomes and Psychosocial Stress by Grobman, William A., Parker, Corette B., Willinger, Marian, Wing, Deborah A., Silver, Robert M., Wapner, Ronald J., Simhan, Hyagriv N., Parry, Samuel, Mercer, Brian M., Haas, David M., Peaceman, Alan M., Hunter, Shannon, Wadhwa, Pathik, Elovitz, Michal A., Foroud, Tatiana, Saade, George, Reddy, Uma M.

“…OBJECTIVE:To assess the relationships between self-reported psychosocial stress and preterm birth, hypertensive disease of pregnancy, and…”
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Blood pressure trajectory and category and risk of hypertensive disorders of pregnancy in nulliparous women by Hauspurg, Alisse, Parry, Samuel, Mercer, Brian M., Grobman, William, Hatfield, Tamera, Silver, Robert M., Parker, Corette B., Haas, David M., Iams, Jay D., Saade, George R., Wapner, Ronald J., Reddy, Uma M., Simhan, Hyagriv

“…Recently updated American College of Cardiology/ American Heart Association (ACC/AHA) guidelines redefine blood pressure categories as stage 1 hypertension…”
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Inadequate weight gain in overweight and obese pregnant women: what is the effect on fetal growth? by Catalano, Patrick M., MD, Mele, Lisa, ScM, Landon, Mark B., MD, Ramin, Susan M., MD, Reddy, Uma M., MD, MPH, Casey, Brian, MD, Wapner, Ronald J., MD, Varner, Michael W., MD, Rouse, Dwight J., MD, Thorp, John M., MD, Saade, George, MD, Sorokin, Yoram, MD, Peaceman, Alan M., MD, Tolosa, Jorge E., MD, MSCE

“…Objective We sought to evaluate inadequate gestational weight gain and fetal growth among overweight and obese women. Study Design We conducted an analysis of…”
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Leukocyte Telomere Length in Newborns: Implications for the Role of Telomeres in Human Disease by Factor-Litvak, Pam, Susser, Ezra, Kezios, Katrina, McKeague, Ian, Kark, Jeremy D, Hoffman, Matthew, Kimura, Masayuki, Wapner, Ronald, Aviv, Abraham

“…In adults, leukocyte telomere length (LTL) is variable, familial, and longer in women and in offspring conceived by older fathers. Although short LTL is…”
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Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals by Breslin, Noelle, Baptiste, Caitlin, Gyamfi-Bannerman, Cynthia, Miller, Russell, Martinez, Rebecca, Bernstein, Kyra, Ring, Laurence, Landau, Ruth, Purisch, Stephanie, Friedman, Alexander M., Fuchs, Karin, Sutton, Desmond, Andrikopoulou, Maria, Rupley, Devon, Sheen, Jean-Ju, Aubey, Janice, Zork, Noelia, Moroz, Leslie, Mourad, Mirella, Wapner, Ronald, Simpson, Lynn L., D’Alton, Mary E., Goffman, Dena

“…Novel coronavirus disease 2019 is rapidly spreading throughout the New York metropolitan area since its first reported case on March 1, 2020. The state is now…”
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A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes by Landon, Mark B, Spong, Catherine Y, Thom, Elizabeth, Carpenter, Marshall W, Ramin, Susan M, Casey, Brian, Wapner, Ronald J, Varner, Michael W, Rouse, Dwight J, Thorp, John M, Sciscione, Anthony, Catalano, Patrick, Harper, Margaret, Saade, George, Lain, Kristine Y, Sorokin, Yoram, Peaceman, Alan M, Tolosa, Jorge E, Anderson, Garland B

“…In this randomized trial of treatment versus no treatment for mild gestational diabetes mellitus, rates of the primary outcome (a composite of stillbirth or…”
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Severe placental abruption: clinical definition and associations with maternal complications by Ananth, Cande V., PhD, MPH, Lavery, Jessica A., MS, Vintzileos, Anthony M., MD, Skupski, Daniel W., MD, Varner, Michael, MD, Saade, George, MD, Biggio, Joseph, MD, Williams, Michelle A., ScD, Wapner, Ronald J., MD, Wright, Jason D., MD

“…Background Placental abruption traditionally is defined as the premature separation of the implanted placenta before the delivery of the fetus. The existing…”
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