Search Results - "Wanotayan, Rujira"
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A deep learning model (FociRad) for automated detection of γ-H2AX foci and radiation dose estimation
Published in Scientific reports (01-04-2022)“…DNA double-strand breaks (DSBs) are the most lethal form of damage to cells from irradiation. γ-H2AX (phosphorylated form of H2AX histone variant) has become…”
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Quantification of histone H2AX phosphorylation in white blood cells induced by ex vivo gamma irradiation of whole blood by both flow cytometry and foci counting as a dose estimation in rapid triage
Published in PloS one (23-03-2022)“…A quick, reliable, and reproducible biological assay to distinguish individuals with possible life-threatening risk following radiological or nuclear incidents…”
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Functional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity
Published in Journal of radiation research (01-05-2021)“…Non-homologous end joining is one of the main pathways for DNA double-strand break (DSB) repair and is also implicated in V(D)J recombination in immune system…”
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Dosimetric Performance of Poly(vinyl alcohol)/Silver Nanoparticles Hybrid Nanomaterials for Colorimetric Sensing of Gamma Radiation
Published in Nanomaterials (Basel, Switzerland) (26-03-2022)“…A colorimetric liquid sensor based on a poly(vinyl alcohol)/silver nanoparticle (PVA/AgNPs) hybrid nanomaterial was developed for gamma radiation in the range…”
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B1 siRNA Increases de novo DNA Methylation of B1 Elements and Promotes Wound Healing in Diabetic Rats
Published in Frontiers in cell and developmental biology (19-01-2022)“…Alu (B1 in rodents) hypomethylation, commonly found in diabetes mellitus patients, increases DNA damage and, consequently, delays the healing process. Alu…”
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The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal
Published in FASEB bioAdvances (01-06-2022)“…The endogenous DNA damage triggering an aging progression in the elderly is prevented in the youth, probably by naturally occurring DNA gaps. Decreased DNA…”
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Asparagine 326 in the extremely C-terminal region of XRCC4 is essential for the cell survival after irradiation
Published in Biochemical and biophysical research communications (20-02-2015)“…XRCC4 is one of the crucial proteins in the repair of DNA double-strand break (DSB) through non-homologous end-joining (NHEJ). As XRCC4 consists of 336 amino…”
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C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin
Published in Biochemical and biophysical research communications (20-09-2013)“…•Chromatin binding of XRCC4 is dependent on the presence of DNA ligase IV.•C-terminal region of DNA ligase IV alone can recruit itself and XRCC4 to…”
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A model of modified meta -iodobenzylguanidine conjugated gold nanoparticles for neuroblastoma treatment
Published in RSC advances (20-07-2021)“…Iodine-131 -iodobenzylguanidine ( I- IBG) has been utilized as a standard treatment to minimize adverse side effects by targeting therapies to bind to the…”
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Lysine 271 but not lysine 210 of XRCC4 is required for the nuclear localization of XRCC4 and DNA ligase IV
Published in Biochemical and biophysical research communications (12-06-2015)“…XRCC4 and DNA Ligase IV (LIG4) cooperate to join two DNA ends at the final step of DNA double-strand break (DSB) repair through non-homologous end-joining…”
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11
Quantification of histone H2AX phosphorylation in white blood cells induced by ex vivo gamma irradiation of whole blood by both flow cytometry and foci counting as a dose estimation in rapid triage
Published in PloS one (01-01-2022)“…A quick, reliable, and reproducible biological assay to distinguish individuals with possible life-threatening risk following radiological or nuclear incidents…”
Get full text
Journal Article -
12
A model of modified -iodobenzylguanidine conjugated gold nanoparticles for neuroblastoma treatment
Published in RSC advances (20-07-2021)“…Iodine-131 meta -iodobenzylguanidine ( 131 I- m IBG) has been utilized as a standard treatment to minimize adverse side effects by targeting therapies to bind…”
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