Search Results - "Wani, Agaz"

Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity by Katrinli, Seyma, Stevens, Jennifer, Wani, Agaz H, Lori, Adriana, Kilaru, Varun, van Rooij, Sanne J H, Hinrichs, Rebecca, Powers, Abigail, Gillespie, Charles F, Michopoulos, Vasiliki, Gautam, Aarti, Jett, Marti, Hammamieh, Rasha, Yang, Ruoting, Wildman, Derek, Qu, Annie, Koenen, Karestan, Aiello, Allison E, Jovanovic, Tanja, Uddin, Monica, Ressler, Kerry J, Smith, Alicia K

“…Post-traumatic stress disorder (PTSD) is a debilitating disorder that develops in some people following trauma exposure. Trauma and PTSD have been associated…”
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Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress by Katrinli, Seyma, Maihofer, Adam X., Wani, Agaz H., Pfeiffer, John R., Ketema, Elizabeth, Ratanatharathorn, Andrew, Baker, Dewleen G., Boks, Marco P., Geuze, Elbert, Kessler, Ronald C., Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Logue, Mark W., Nievergelt, Caroline M., Smith, Alicia K., Uddin, Monica

“…Epigenetic factors modify the effects of environmental factors on biological outcomes. Identification of epigenetic changes that associate with PTSD is…”
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Differentially expressed heterogeneous overdispersion genes testing for count data by Yuan, Yubai, Xu, Qi, Wani, Agaz, Dahrendorff, Jan, Wang, Chengqi, Shen, Arlina, Donglasan, Janelle, Burgan, Sarah, Graham, Zachary, Uddin, Monica, Wildman, Derek, Qu, Annie

“…The mRNA-seq data analysis is a powerful technology for inferring information from biological systems of interest. Specifically, the sequenced RNA fragments…”
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The impact of psychopathology, social adversity and stress-relevant DNA methylation on prospective risk for post-traumatic stress: A machine learning approach by Wani, Agaz H., Aiello, Allison E., Kim, Grace S., Xue, Fei, Martin, Chantel L., Ratanatharathorn, Andrew, Qu, Annie, Koenen, Karestan, Galea, Sandro, Wildman, Derek E., Uddin, Monica

“…•A complex etiology and clinical course make identification of people at higher risk of post-traumatic symptom disorder (PTSD) challenging.•Machine learning…”
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DNA methylation of Nuclear Factor of Activated T Cells 1 mediates the prospective relation between exposure to different traumatic event types and post-traumatic stress disorder by Occean, James R., Wani, Agaz H., Donglasan, Janelle, Aiello, Allison E., Galea, Sandro, Koenen, Karestan C., Qu, Annie, Wildman, Derek E., Uddin, Monica

“…•Exposure to different trauma types is associated with differences in conditional risk for post-traumatic stress disorder (PTSD).•DNA methylation at three…”
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A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke by Soremekun, Opeyemi, Musanabaganwa, Clarisse, Uwineza, Annette, Ardissino, Maddalena, Rajasundaram, Skanda, Wani, Agaz H., Jansen, Stefan, Mutabaruka, Jean, Rutembesa, Eugene, Soremekun, Chisom, Cheickna, Cisse, Wele, Mamadou, Mugisha, Joseph, Nash, Oyekanmi, Kinyanda, Eugene, Nitsch, Dorothea, Fornage, Myriam, Chikowore, Tinashe, Gill, Dipender, Wildman, Derek E., Mutesa, Leon, Uddin, Monica, Fatumo, Segun

“…Observational studies have shown an association between post-traumatic stress disorder (PTSD) and ischemic stroke (IS) but given the susceptibility to…”
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Leukocyte methylomic imprints of exposure to the genocide against the Tutsi in Rwanda: a pilot epigenome-wide analysis by Musanabaganwa, Clarisse, Wani, Agaz H, Donglasan, Janelle, Fatumo, Segun, Jansen, Stefan, Mutabaruka, Jean, Rutembesa, Eugene, Uwineza, Annette, Hermans, Erno J, Roozendaal, Benno, Wildman, Derek E, Mutesa, Leon, Uddin, Monica

“…We conducted a pilot epigenome-wide association study of women from Tutsi ethnicity exposed to the genocide while pregnant and their resulting offspring, and a…”
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Serum lead, mercury, manganese, and copper and DNA methylation age among adults in Detroit, Michigan by Lodge, Evans K, Dhingra, Radhika, Martin, Chantel L, Fry, Rebecca C, White, Alexandra J, Ward-Caviness, Cavin K, Wani, Agaz H, Uddin, Monica, Wildman, Derek E, Galea, Sandro, Aiello, Allison E

“…Although the effects of lead, mercury, manganese, and copper on individual disease processes are well understood, estimating the health effects of long-term…”
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Uncovering host-microbiome interactions in global systems with collaborative programming: a novel approach integrating social and data sciences [version 1; peer review: 1 approved with reservations] by Oberstaller, Jenna, Adapa, Swamy Rakesh, Dayhoff II, Guy W, Gibbons, Justin, Keller, Thomas E, Li, Chang, Lim, Jean, Pham, Minh, Sarkar, Anujit, Sharma, Ravi, Wani, Agaz H, Vianello, Andrea, Duong, Linh M, Wang, Chenggi, Atkinson, Celine Grace F, Barrow, Madeleine, Van Bibber, Nathan W, Dahrendorff, Jan, Dean, David A. E, Dokur, Omkar, Ferreira, Gloria C, Hastings, Mitchell, Herbert, Gregory S, Huq, Khandaker Tasnim, Kim, Youngchul, Liao, Xiangyun, Liu, XiaoMing, Mansuri, Fahad, Martin, Lynn B, Miller, Elizabeth M, Natarajan, Ojas, Pang, Jinyong, Prieto, Francesca, Radulovic, Peter W, Sheth, Vyoma, Sumpter, Matthew, Sutherland, Desirae, Vijayakumar, Nisha, Jiang, Rays H. Y

“…Microbiome data are undergoing exponential growth powered by rapid technological advancement. As the scope and depth of microbiome research increases,…”
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Genome-Wide Meta-Analysis of DNA Methylation and PTSD in 23 Military and Civilian Cohorts and Multi-Omic Analysis Point Toward Immune Mechanisms by Logue, Mark, Katrinli, Seyma, Wani, Agaz H., Maihofer, Adam, Zannas, Anthony, Nugent, Nicole R., Zhao, Xiang, Nievergelt, Caroline M., Uddin, Monica, Smith, Alicia

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Epigenome-Wide Meta-Analysis of 11 Military and Civilian Cohorts Reveals Cell-Type Specific and Inflammatory DNA Methylation Patterns Associated With PTSD by Katrinli, Seyma, Wani, Agaz, Zhao, Xiang, Maihofer, Adam X., Zhao, Ying, Nunez, Diana, Montalvo-Ortiz, Janitza, Zannas, Anthony, Logue, Mark W., Nievergelt, Caroline M., Uddin, Monica, Smith, Alicia

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LEVERAGING MULTI-OMIC DATA TO INTERPRET AN EPIGENOME-WIDE META-ANALYSIS OF PTSD IN 23 MILITARY AND CIVILIAN COHORTS by Smith, Alicia, Katrinli, Seyma, Wani, Agaz H., Maihofer, Adam X., Zannas, Anthony S, Nugent, Nicole, Xhao, Xiang, Nievergelt, Caroline M., Uddin, Monica, Logue, Mark

“…Epigenetic factors, including DNA methylation (DNAm), are impacted by traumatic stress, and may help to distinguish between individuals with and without…”
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25. EPIGENOME-WIDE META-ANALYSIS OF > 3200 MILITARY AND CIVILIAN PARTICIPANTS IDENTIFIES CELL-TYPE SPECIFIC DNA METHYLATION SIGNALS ASSOCIATED WITH PTSD by Katrinli, Seyma, Wani, Agaz H., Zhao, Xiang, Maihofer, Adam X., Zhao, Ying, Nunez, Diana, Montalvo-Ortiz, Janitza, Zannas, Anthony S., Logue, Mark, Nievergelt, Caroline M., Uddin, Monica, Smith, Alicia K.

“…The link between posttraumatic stress disorder (PTSD) and the immune system is supported by multiple studies that identified DNA methylation (DNAm) differences…”
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Cell-Type Specific Methylation Analysis Reveals Multiple Loci Associated With PTSD in African Americans by Katrinli, Seyma, Wani, Agaz, Gautam, Aarti, Hammamieh, Rasha, Yang, Ruoting, Kilaru, Varun, Lori, Adriana, Powers, Abigail, Hinrichs, Rebecca, Gillespie, Charles F., Wingo, Aliza P., Michopoulos, Vasiliki, Jovanovic, Tanja, Jett, Marti, Uddin, Monica, Ressler, Kerry, Smith, Alicia

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The Impact of Psychopathology, Social Adversity and Stress-relevant DNAm on Prospective Risk for Post-traumatic Stress: A Machine Learning Approach by Wani, Agaz H., Aiello, Allison E., Kim, Grace S., Xue, Fei, Martin, Chantel L., Ratanatharathorn, Andrew, Qu, Annie, Koenen, Karestan, Galea, Sandro, Wildman, Derek E., Uddin, Monica

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Blood-Based DNA Methylation and Exposure Risk Score Predicts PTSD With High Accuracy in Military and Civilian Cohorts by Wani, Agaz H., Zhao, Xiang, Katrinli, Seyma, Ketema, Elizabeth, Maihofer, Adam X., Aiello, Allison E., Boks, Marco P., Rutten, Bart PF, Baker, Dewleen G., Stein, Murray B., Ressler, Kerry J., Miller, Mark W., Wildman, Derek, Wolf, Erika, Logue, Mark W., Nievergelt, Caroline M., Smith, Alicia K., Uddin, Monica

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Epigenome-Wide Meta-Analysis of 13 Military and Civilian Cohorts Reveals Common and Cell-Type Specific DNA Methylation Patterns Associated With PTSD by Katrinli, Seyma, Wani, Agaz, Maihofer, Adam, Aiello, Allison, Baker, Dewleen, Boks, Marco, King, Anthony, Koen, Nastassja, Mehta, Divya, Nugent, Nicole, Orcutt, Holly, Rauch, Sheila, Ressler, Kerry, Rutten, Bart, Stein, Dan, Stein, Murray, Wildman, Derek, Logue, Mark, Nievergelt, Caroline, Uddin, Monica, Smith, Alicia

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P626. Epigenome-Wide Meta-Analysis of >2100 Military and Civilian Participants Reveals New DNA Methylation Patterns Associated With PTSD by Katrinli, Seyma, Wani, Agaz H., Maihofer, Adam X., Aiello, Allison E., Baker, Dewleen G., Boks, Marco P., King, Anthony P., Koen, Nastassja, Mehta, Divya, Nugent, Nicole R., Orcutt, Holly K., Rauch, Sheila, Ressler, Kerry J., Rutten, Bart PF, Stein, Dan J., Stein, Murray B., Wildman, Derek, Young, Ross M., Logue, Mark W., Nievergelt, Caroline M., Uddin, Monica, Smith, Alicia K.

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P629. Establishing a DNA Methylation and Exposure Risk Score for PTSD Using Machine Learning by Wani, Agaz H., Katrinli, Seyma, Ketema, Elizabeth, Maihofer, Adam X., Aiello, Allison E., Boks, Marco P., Rutten, Bart PF, Baker, Dewleen G., Stein, Murray B., Ressler, Kerry J., Wildman, Derek E., Logue, Mark W., Nievergelt, Caroline M., Smith, Alicia K., Uddin, Monica

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Differentially expressed heterogeneous overdispersion genes testing for count data by Yubai Yuan, Qi Xu, Agaz Wani, Jan Dahrendorff, Chengqi Wang, Arlina Shen, Janelle Donglasan, Sarah Burgan, Zachary Graham, Monica Uddin, Derek Wildman, Annie Qu

“…The mRNA-seq data analysis is a powerful technology for inferring information from biological systems of interest. Specifically, the sequenced RNA fragments…”
Get full text