Search Results - "Wang, Zhishan"

The Epitranscriptomic Mechanism of Metal Toxicity and Carcinogenesis by Yang, Chengfeng, Wang, Zhishan

“…Metals are common toxic environmental pollutants. Acute or chronic exposure to metal pollutants causes severe adverse health effects in animals and humans,…”
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MicroRNA Regulation of Breast Cancer Stemness by Humphries, Brock, Wang, Zhishan, Yang, Chengfeng

“…Recent advances in our understanding of breast cancer have demonstrated that cancer stem-like cells (CSCs, also known as tumor-initiating cell (TICs)) are…”
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Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression by Wang, Zhishan, Yang, Ping, Xie, Jie, Lin, Hsuan-Pei, Kumagai, Kazuyoshi, Harkema, Jack, Yang, Chengfeng

“…•Arsenic and BaP co-exposure acts synergistically in inducing CSC-like property.•Arsenic and BaP combined oral exposure acts synergistically in increasing lung…”
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Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses by Humphries, Brock, Wang, Zhishan, Yang, Chengfeng

“…Rho GTPases, a family of the Ras GTPase superfamily, are key regulators of the actin cytoskeleton. They were originally thought to primarily affect cell…”
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The role of microRNAs in metal carcinogen-induced cell malignant transformation and tumorigenesis by Humphries, Brock, Wang, Zhishan, Yang, Chengfeng

“…MicroRNAs (miRNAs), an important component of epigenetic mechanisms of carcinogenesis, have been shown to play crucial roles in cancer initiation, metastasis,…”
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biSAMNet: A Novel Approach in Maritime Data Completion Using Deep Learning and NLP Techniques by Li, Yong, Wang, Zhishan

“…In the extensive monitoring of maritime traffic, maritime management frequently encounters incomplete automatic identification system (AIS) data. This…”
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A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis by Nan, Aruo, Chen, Lijian, Zhang, Nan, Liu, Zhenzhong, Yang, Ti, Wang, Zhishan, Yang, Chengfeng, Jiang, Yiguo

“…Lead is a metal that has toxic effects on the developing nervous system. However, the mechanisms underlying lead-induced neurotoxicity are not well understood…”
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Up-regulation of RNA m6A methyltransferase like-3 expression contributes to arsenic and benzo[a]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis by Wang, Zhishan, Uddin, Mohammad Burhan, Wang, Po-Shun, Liu, Zulong, Barzideh, David, Yang, Chengfeng

“…While arsenic or BaP alone exposure can cause lung cancer, studies showed that arsenic plus BaP co-exposure displays a significantly stronger lung tumorigenic…”
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MiR-205 Dysregulations in Breast Cancer: The Complexity and Opportunities by Xiao, Yajuan, Humphries, Brock, Yang, Chengfeng, Wang, Zhishan

“…MicroRNAs (miRNAs) are endogenous non-coding small RNAs that downregulate target gene expression by imperfect base-pairing with the 3' untranslated regions…”
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The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis by Uddin, Mohammad Burhan, Wang, Zhishan, Yang, Chengfeng

“…Abstract The m 6 A RNA methylation is the most prevalent internal modification in mammalian mRNAs which plays critical biological roles by regulating vital…”
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Long noncoding RNA ABHD11-AS1 interacts with SART3 and regulates CD44 RNA alternative splicing to promote lung carcinogenesis by Wang, Po-Shun, Liu, Zulong, Sweef, Osama, Xie, Jie, Chen, Jing, Zhu, Haining, Zeidler-Erdely, Patti C., Yang, Chengfeng, Wang, Zhishan

“…[Display omitted] •Cr(VI) exposure increases the lncRNA ABHD11-AS1 expression.•ABHD11-AS1 plays a key role in Cr(VI)-induced cell transformation and…”
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Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b by Wang, Zhishan, Zhao, Yong, Smith, Eric, Goodall, Gregory J, Drew, Paul A, Brabletz, Thomas, Yang, Chengfeng

“…Arsenic is a well-recognized human carcinogen, yet the mechanism by which it causes human cancer has not been elucidated. MicroRNAs (miRNAs) are a big family…”
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The Oncogenic and Tumor Suppressive Long Non-Coding RNA-microRNA-Messenger RNA Regulatory Axes Identified by Analyzing Multiple Platform Omics Data from Cr(VI)-Transformed Cells and Their Implications in Lung Cancer by Sweef, Osama, Yang, Chengfeng, Wang, Zhishan

“…Chronic exposure to hexavalent chromium (Cr(VI)) causes lung cancer in humans, however, the underlying mechanism has not been well understood. Long non-coding…”
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Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells by Zhao, Yong, Wang, Zhishan, Jiang, Yiguo, Yang, Chengfeng

“…Highlights ► Rac1 activation promotes breast cancer cell proliferation and migration. ► Rac1 is highly activated in IGF-IR overexpression or PTEN deficient…”
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Akt Activation Is Responsible for Enhanced Migratory and Invasive Behavior of Arsenic-Transformed Human Bronchial Epithelial Cells by Wang, Zhishan, Yang, Junling, Fisher, Theresa, Xiao, Hua, Jiang, Yiguo, Yang, Chengfeng

“…Background: Arsenic is one of the most common environmental contaminants. Long-term exposure to arsenic causes human bronchial epithelial cell (HBEC) malignant…”
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Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer-Challenges and Opportunities by Li, Yunfei, Humphries, Brock, Yang, Chengfeng, Wang, Zhishan

“…Breast cancer (BC) is the second leading cause of cancer-related death in American women and more than 90% of BC-related death is caused by metastatic BC…”
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Construction of a large-scale maritime element semantic schema based on knowledge graph models for unmanned automated decision-making by Li, Yong, Liu, Xiaotong, Wang, Zhishan, Mei, Qiang, Xie, Wenxin, Yang, Yang, Wang, Peng

“…In maritime logistics optimization, considerable research efforts are focused on the extraction of deep behavioral characteristics from comprehensive shipping…”
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Research on the carbon emissions traceability inventory and multi-horizon prediction of ship carbon emissions: a case study of Tianjin Port by Li, Yong, Xie, Wenxin, Yang, Yang, Mei, Qiang, Wang, Zhishan, Li, Zhaoxuan, Wang, Peng

“…Introduction In recent years, the adverse effects of escalating maritime trade and international shipping– particularly in regard to increased greenhouse gas…”
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Maritime greenhouse gas emission estimation and forecasting through AIS data analytics: a case study of Tianjin port in the context of sustainable development by Xie, Wenxin, Li, Yong, Yang, Yang, Wang, Peng, Wang, Zhishan, Li, Zhaoxuan, Mei, Qiang, Sun, Yaqi

“…The escalating greenhouse gas (GHG) emissions from maritime trade present a serious environmental and biological threat. With increasing emission reduction…”
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Research on Multi-Port Ship Traffic Prediction Method Based on Spatiotemporal Graph Neural Networks by Li, Yong, Li, Zhaoxuan, Mei, Qiang, Wang, Peng, Hu, Wenlong, Wang, Zhishan, Xie, Wenxin, Yang, Yang, Chen, Yuhaoran

“…The intelligent maritime transportation system has emerged as a pivotal component in port management, owing to the rapid advancements in artificial…”
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