Search Results - "Wang, Zhiren"

Constraining the Existence of Axion Clouds in M87 with Closure Trace Analyses by Wang, Zhiren, Broderick, Avery E.

“…Abstract Black holes can amplify incoming bosonic waves via rotational superradiance, inducing bound states of ultralight bosons around them. This phenomenon…”
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Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer’s Disease by Wang, Zhiren, Wang, Yali, Wang, Bo, Li, Wenrui, Huang, Ling, Li, Xingshu

“…A novel series of clioquinol-moracin hybrids were designed and synthesized by fusing the pharmacophores of clioquinol and moracin M, and their activities as…”
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Gut Microbiome Composition Associated With Major Depressive Disorder and Sleep Quality by Zhang, Qi, Yun, Yajun, An, Huimei, Zhao, Wenxuan, Ma, Ting, Wang, Zhiren, Yang, Fude

“…The microbiota–gut–brain axis plays a critical role in the pathogenesis of major depressive disorder (MDD) and related subclinical symptoms. However, studies…”
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Lipid-Based Nanotechnology: Liposome by Jiang, Yanhao, Li, Wenpan, Wang, Zhiren, Lu, Jianqin

“…Over the past several decades, liposomes have been extensively developed and used for various clinical applications such as in pharmaceutical, cosmetic, and…”
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Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline–Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer’s Disease by Wang, Zhiren, Hu, Jinhui, Yang, Xiaoping, Feng, Xing, Li, Xingshu, Huang, Ling, Chan, Albert S. C

“…A novel series of quinoline–indole derivatives were synthesized and evaluated as multitarget-directed ligands for the treatment of Alzheimer’s disease (AD)…”
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Cholesterol-modified sphingomyelin chimeric lipid bilayer for improved therapeutic delivery by Wang, Zhiren, Li, Wenpan, Jiang, Yanhao, Park, Jonghan, Gonzalez, Karina Marie, Wu, Xiangmeng, Zhang, Qing-Yu, Lu, Jianqin

“…Cholesterol (Chol) fortifies packing and reduces fluidity and permeability of the lipid bilayer in vesicles (liposomes)-mediated drug delivery. However, under…”
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Bibliometric Analysis of the Research Status and Global Trends in Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease from 2002 to 2022 by Cai, Haipeng, Du, Ruonan, Yang, Kebing, Li, Wei, Wang, Zhiren

“…Several reviews on behavioral and psychological symptoms (BPSDs) in patients with Alzheimer's disease (AD) have summarized the current state of this field, but…”
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Association between electroconvulsive therapy and depressive disorder from 2012 to 2021: Bibliometric analysis and global trends by Cai, Haipeng, Du, Ruonan, Yang, Kebing, Li, Wei, Wang, Zhiren

“…Background Depressive disorder is a chronic mental illness that is vulnerable to relapse, imposes a huge economic burden on society and patients, and is a…”
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Novel application of metformin combined with targeted drugs on anticancer treatment by Deng, Jun, Peng, Mei, Wang, Zhiren, Zhou, Sichun, Xiao, Di, Deng, Jiating, Yang, Xue, Peng, Jingyuan, Yang, Xiaoping

“…The success of targeted drug therapies for treating cancer patients has attracted broad attention both in the academic community and social society. However,…”
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Research status and global trends of late-life depression from 2004 to 2023: bibliometric analysis by Du, Ruonan, Yang, Kebing, Li, Wei, Wang, Zhiren, Cai, Haipeng

“…Global research hotspots and future research trends in the neurobiological mechanisms of late-life depression (LLD) as well as its diagnosis and treatment are…”
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A novel animal model of spontaneous epilepsy: Cdk5 knockout in pericyte-specific mice by Lin, Lin, Hu, Xiaofei, Hong, Weijun, Pan, Tengwei, Wang, Zhiren, Wang, En, Wu, Gang

“…Changes in neurovascular unit components and their interactions play a crucial role in epileptogenesis and the pathological process of epilepsy. Currently,…”
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Knowledge domain and trends in treatment-resistant schizophrenia (TRS) research based on CiteSpace bibliometrics analysis by Cai, Haipeng, Du, Ruonan, Zhang, Jianyi, Wang, Xin, Li, Wei, Yang, Kebing, Wang, Zhiren

“…Background Although the number of studies on treatment-resistant schizophrenia (TRS) has been increasing, the global research hotspots and future research…”
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Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy by Wang, Zhiren, Li, Wenpan, Jiang, Yanhao, Tran, Tuyen Ba, Cordova, Leyla Estrella, Chung, Jinha, Kim, Minhyeok, Wondrak, Georg, Erdrich, Jennifer, Lu, Jianqin

“…Epacadostat (EPA), the most advanced IDO1 inhibitor, in combination with PD-1 checkpoint inhibitor, has failed in a recent Phase III clinical trial for…”
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Synthesis, Anti-Proliferative Evaluation and Mechanism of 4-Trifluoro Methoxy Proguanil Derivatives with Various Carbon Chain Length by Xu, Simeng, Cao, Yufang, Luo, Yu, Xiao, Di, Wang, Wei, Wang, Zhiren, Yang, Xiaoping

“…Among the known biguanide drugs, proguanil has the best antiproliferative activity. In contrast, newly synthesized biguanide derivatives containing fluorine…”
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A correlation study of intestinal microflora and first‐episode depression in Chinese patients and healthy volunteers by Zheng, Shaojun, Zhu, Yubing, Wu, Weidong, Zhang, Qi, Wang, Yongqian, Wang, Zhiren, Yang, Fude

“…Objective This research examines the intestinal‐associated flora of patients with depression compared with healthy volunteers to identify the characteristics…”
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White Matter in Schizophrenia Treatment Resistance by Kochunov, Peter, Huang, Junchao, Chen, Song, Li, Yanli, Tan, Shuping, Fan, Fengmei, Feng, Wei, Wang, Yunhui, Rowland, Laura M, Savransky, Anya, Du, Xiaoming, Chiappelli, Joshua, Chen, Shuo, Jahanshad, Neda, Thompson, Paul M, Ryan, Meghann C, Adhikari, Bhim, Sampath, Hemalatha, Cui, Yimin, Wang, Zhiren, Yang, Fude, Tan, Yunlong, Hong, L Elliot

“…Failure of antipsychotic medications to resolve symptoms in patients with schizophrenia creates a clinical challenge that is known as treatment resistance. The…”
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Subcortical structures and cognitive dysfunction in first episode schizophrenia by Fan, Fengmei, Xiang, Hong, Tan, Shuping, Yang, Fude, Fan, Hongzhen, Guo, Hua, Kochunov, Peter, Wang, Zhiren, Hong, L. Elliot, Tan, Yunlong

“…•All domains of cognitive function were significantly lower in patients with first episode schizophrenia.•Patients showed significantly smaller volumes in…”
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Design, Synthesis, and Evaluation of Multitarget-Directed Selenium-Containing Clioquinol Derivatives for the Treatment of Alzheimer’s Disease by Wang, Zhiren, Wang, Yali, Li, Wenrui, Mao, Fei, Sun, Yang, Huang, Ling, Li, Xingshu

“…A series of selenium-containing clioquinol derivatives were designed, synthesized, and evaluated as multifunctional anti-Alzheimer’s disease (AD) agents. In…”
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Assessment of psychological personality traits in transgender groups using the Minnesota multiphasic personality inventory by Liu, Yan, Wang, Zhanqiang, Dong, Hanwen, Zhang, Yueqian, Yang, Kebing, Yang, Qingyan, Wang, Zhiren, Niu, Yajuan

“…To explore the psychological personality characteristics of transgender groups and to determine whether these characteristics differ according to…”
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Identifying the difference in time perception between major depressive disorder and bipolar depression through a temporal bisection task by Liu, Panqi, Guo, Hua, Ma, Ruihua, Liu, Sijia, Wang, Xuan, Zhao, Ke, Tan, Yunlong, Tan, Shuping, Yang, Fude, Wang, Zhiren

“…It is difficult to make a precise diagnosis to distinguish patients with Major Depressive Disorder (MDD) from patients with Bipolar Depressive Disorder…”
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