Search Results - "Wang, Yanchang"
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Light- and Temperature-Induced Expression of an R2R3-MYB Gene Regulates Anthocyanin Biosynthesis in Red-Fleshed Kiwifruit
Published in International journal of molecular sciences (22-10-2019)“…The R2R3 MYB genes associated with the flavonoid/anthocyanidin pathway feature two repeats, and represent the most abundant classes of MYB genes in plants;…”
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The role of SUMOylation in biomolecular condensate dynamics and protein localization
Published in Cell insight (01-12-2024)“…As a type of protein post-translational modification, SUMOylation is the process that attaches a small ubiquitin-like modifier (SUMO) to lysine residues of…”
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signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment
Published in Proceedings of the National Academy of Sciences - PNAS (24-12-2013)“…Improper kinetochore attachments activate the spindle assembly checkpoint (SAC) to prevent anaphase onset, but it is poorly understood how this checkpoint is…”
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The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins
Published in Cells (Basel, Switzerland) (21-10-2021)“…Protein misfolding and aggregation are implicated in many neurodegenerative diseases. One of these diseases is Huntington's, which is caused by increased…”
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Reversible and Fast (De)fluorination of High‐Capacity Cu2O Cathode: One Step Toward Practically Applicable All‐Solid‐State Fluoride‐Ion Battery
Published in Advanced energy materials (01-12-2021)“…All‐solid‐state fluoride‐ion batteries (FIBs) are regarded as promising energy storage devices; however, currently proposed cathodes fail to meet the…”
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The current view for the silencing of the spindle assembly checkpoint
Published in Cell cycle (Georgetown, Tex.) (01-06-2014)“…Chromosome bipolar attachment is achieved when sister kinetochores are attached by microtubules emanating from opposite spindle poles, and this process is…”
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Steam reforming of tar compounds over Ni/olivine catalysts doped with CeO2
Published in Energy conversion and management (2007)Get full text
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Anion Substitution at Apical Sites of Ruddlesden–Popper-type Cathodes toward High Power Density for All-Solid-State Fluoride-Ion Batteries
Published in Chemistry of materials (25-01-2022)“…All-solid-state fluoride-ion batteries (FIBs) that use fluoride ions as carrier ions offer a new horizon for next-generation energy storage devices owing to…”
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Yeast Fin1-PP1 dephosphorylates an Ipl1 substrate, Ndc80, to remove Bub1-Bub3 checkpoint proteins from the kinetochore during anaphase
Published in PLoS genetics (25-05-2021)“…The spindle assembly checkpoint (SAC) prevents anaphase onset in response to chromosome attachment defects, and SAC silencing is essential for anaphase onset…”
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Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method
Published in Molecules (Basel, Switzerland) (29-08-2019)“…Fungal infection is a leading cause of mortality in immunocompromised population; thus, it is urgent to develop new and safe antifungal agents. Different from…”
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The polySUMOylation axis promotes nucleolar release of Tof2 for mitotic exit
Published in Cell reports (Cambridge) (23-07-2024)“…In budding yeast, the nucleolus serves as the site to sequester Cdc14, a phosphatase essential for mitotic exit. Nucleolar proteins Tof2, Net1, and Fob1 are…”
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Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin
Published in Molecular biology of the cell (01-07-2016)“…Ubiquilin proteins contain a ubiquitin-like domain (UBL) and ubiquitin-associated domain(s) that interact with the proteasome and ubiquitinated substrates,…”
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Small molecules targeting Pin1 as potent anticancer drugs
Published in Frontiers in pharmacology (27-03-2023)“…Pin1 is a member of the evolutionarily conserved peptidyl-prolyl isomerase (PPIase) family of proteins. Following phosphorylation, Pin1-catalyzed…”
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The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins
Published in PloS one (18-01-2018)“…The functionality of a protein depends on its correct folding, but newly synthesized proteins are susceptible to aberrant folding and aggregation. Heat shock…”
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Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA–BamD Interaction
Published in Frontiers in microbiology (19-06-2020)“…The demand for novel antibiotics is imperative for drug-resistant Gram-negative bacteria which causes diverse intractable infection disease in clinic. Here, a…”
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A new layer of regulation is required to silence the DNA damage checkpoint
Published in Cell cycle (Georgetown, Tex.) (15-09-2010)“…Comment on: Wood MD, et al. Cell Cycle 2010; 9:3354-64…”
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Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation
Published in Cells (Basel, Switzerland) (07-07-2022)“…Accurate chromosome segregation depends on bipolar chromosome–microtubule attachment and tension generation on chromosomes. Incorrect chromosome attachment…”
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The Cdc48 Complex Alleviates the Cytotoxicity of Misfolded Proteins by Regulating Ubiquitin Homeostasis
Published in Cell reports (Cambridge) (14-07-2020)“…The accumulation of misfolded proteins is associated with multiple neurodegenerative disorders, but it remains poorly defined how this accumulation causes…”
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Fin1-PP1 Helps Clear Spindle Assembly Checkpoint Protein Bub1 from Kinetochores in Anaphase
Published in Cell reports (Cambridge) (09-02-2016)“…The spindle assembly checkpoint (SAC) monitors chromosome attachment defects, and the assembly of SAC proteins at kinetochores is essential for its activation,…”
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Protocol for high-throughput screening of SARS-CoV-2 main protease inhibitors using a robust fluorescence polarization assay
Published in STAR protocols (16-12-2022)“…Discovery of efficacious antiviral agents targeting SARS-CoV-2 main protease (Mpro) is of the highest importance to fight against COVID-19. Here, we describe a…”
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