Search Results - "Wang, Yan Dong"
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The Relationship Between Gut Microbiota and Inflammatory Diseases: The Role of Macrophages
Published in Frontiers in microbiology (09-06-2020)“…Gut microbiota, an integral part of the human body, comprise bacteria, fungi, archaea, and protozoa. There is consensus that the disruption of the gut…”
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The roles of the gut microbiota-miRNA interaction in the host pathophysiology
Published in Molecular medicine (Cambridge, Mass.) (07-11-2020)“…The gut microbiota regulates the biological processes of organisms acting like 'another' genome, affecting the health and disease of the host. MicroRNAs, as…”
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Gut Microbiota: An Integral Moderator in Health and Disease
Published in Frontiers in microbiology (21-02-2018)“…The gut microbiota, as the main member in gut microecology, is an essential mediator in health and disease. The gut microbiota interacts with various organs…”
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Hierarchical crack buffering triples ductility in eutectic herringbone high-entropy alloys
Published in Science (American Association for the Advancement of Science) (20-08-2021)“…High-entropy herringbone alloy Eutectic high-entropy alloys have a dual phase structure that could be useful for optimizing a material’s properties. Shi et al…”
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Temperature-dependent micromechanical behavior of medium-Mn transformation-induced-plasticity steel studied by in situ synchrotron X-ray diffraction
Published in Acta materialia (01-12-2017)“…The temperature-dependent micromechanical behavior of medium-Mn transformation-induced-plasticity (TRIP) steel with a nominal chemical composition of…”
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The G‐Protein‐coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light‐chain enhancer of activated B cells (NF‐κB) in mice
Published in Hepatology (Baltimore, Md.) (01-10-2011)“…Gpbar1 (TGR5), a membrane‐bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays…”
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Emerging Role of Non-Coding RNAs in Esophageal Squamous Cell Carcinoma
Published in International journal of molecular sciences (30-12-2019)“…Esophageal squamous cell carcinoma (ESCC) is a highly prevalent tumor and is associated with ethnicity, genetics, and dietary intake. Non-coding RNAs (ncRNAs),…”
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DAF-16/FOXO Transcription Factor in Aging and Longevity
Published in Frontiers in pharmacology (23-08-2017)“…Aging is associated with age-related diseases and an increase susceptibility of cancer. Dissecting the molecular mechanisms that underlie aging and longevity…”
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Emerging Roles of Wnt Ligands in Human Colorectal Cancer
Published in Frontiers in oncology (14-08-2020)“…Colorectal cancer (CRC) is the fourth leading cause of cancer death worldwide, and constitutive activation of the Wnt signaling pathway is universal in most…”
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Roles and Mechanisms of Long Non-Coding RNAs in Breast Cancer
Published in International journal of molecular sciences (21-12-2022)“…Breast cancer is a major health threat and the second leading cause of cancer-related deaths in women worldwide. The detailed mechanisms involved in the…”
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Unprecedented non-hysteretic superelasticity of [001]-oriented NiCoFeGa single crystals
Published in Nature materials (01-07-2020)“…Superelasticity associated with the martensitic transformation has found a broad range of engineering applications 1 , 2 . However, the intrinsic hysteresis 3…”
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GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells
Published in PloS one (01-04-2014)“…GPBAR1/TGR5 is a novel plasma membrane-bound G protein-coupled bile acid (BA) receptor. BAs are known to induce the expression of inflammatory cytokines in the…”
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Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response
Published in Hepatology (Baltimore, Md.) (01-11-2008)“…The farnesoid X receptor (FXR) is a nuclear receptor that plays key roles in hepatoprotection by maintaining the homeostasis of liver metabolism. FXR null mice…”
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Investigation of the high-temperature fatigue mechanism related to altered local short-range order in AL6XN austenitic stainless steel
Published in Materials & design (01-12-2023)“…An increase in crystal local short-range order (SRO), characterized by obvious diffuse intensity maxima at 1/3{422} in the [111]-axis selected area diffraction…”
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Effect of Al addition on the microstructures and deformation behaviors of non-equiatomic FeMnCoCr metastable high entropy alloys
Published in Applied physics letters (27-12-2021)“…The phase stability, mechanical behaviors, and deformation mechanism among a series of Fe48-xMn32Co10Cr10Alx metastable high entropy alloys (HEAs) with…”
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HGF/c-MET: A Promising Therapeutic Target in the Digestive System Cancers
Published in International journal of molecular sciences (23-10-2018)“…The HGF/c-MET pathway is active in the development of digestive system cancers, indicating that inhibition of HGF/c-MET signaling may have therapeutic…”
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Activation of the G Protein-Coupled Bile Acid Receptor TGR5 Modulates the HCP5/miR-139-5p/DDIT4 Axis to Antagonize Cervical Cancer Progression
Published in International journal of molecular sciences (16-08-2024)“…A growing body of evidence indicates that the G protein-coupled bile acid receptor, TGR5, plays a critical role in multiple physiological processes ranging…”
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Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice
Published in Hepatology (Baltimore, Md.) (01-12-2012)“…Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and is the primary bile acid receptor. We previously showed that FXR was required…”
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Nuclear receptors: a bridge linking the gut microbiome and the host
Published in Molecular medicine (Cambridge, Mass.) (05-11-2021)“…The gut microbiome is the totality of microorganisms, bacteria, viruses, protozoa, and fungi within the gastrointestinal tract. The gut microbiome plays key…”
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LRP5 promotes cancer stem cell traits and chemoresistance in colorectal cancer
Published in Journal of cellular and molecular medicine (01-02-2022)“…The overactivation of canonical Wnt/β‐catenin pathway and the maintenance of cancer stem cells (CSCs) are essential for the onset and malignant progression of…”
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